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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 25

Publication Record


A Deep Hydrophobic Binding Cavity is the Main Interaction for Different Y R Antagonists.
Burkert K, Zellmann T, Meier R, Kaiser A, Stichel J, Meiler J, Mittapalli GK, Roberts E, Beck-Sickinger AG
(2017) ChemMedChem 12: 75-85
MeSH Terms: Animals, Arginine, Benzazepines, Binding Sites, COS Cells, Cells, Cultured, Chlorocebus aethiops, Dose-Response Relationship, Drug, HEK293 Cells, Humans, Hydrophobic and Hydrophilic Interactions, Molecular Docking Simulation, Molecular Structure, Receptors, Neuropeptide Y, Structure-Activity Relationship
Added April 8, 2017
1 Communities
1 Members
0 Resources
15 MeSH Terms
Virulence factors enhance Citrobacter rodentium expansion through aerobic respiration.
Lopez CA, Miller BM, Rivera-Chávez F, Velazquez EM, Byndloss MX, Chávez-Arroyo A, Lokken KL, Tsolis RM, Winter SE, Bäumler AJ
(2016) Science 353: 1249-53
MeSH Terms: Aerobiosis, Amyloid Precursor Protein Secretases, Animals, Citrobacter rodentium, Colitis, Colon, Cytochromes, Dibenzazepines, Electron Transport Chain Complex Proteins, Enterobacteriaceae Infections, Gene Deletion, Hyperplasia, Intestinal Mucosa, Ki-67 Antigen, Mice, Mice, Inbred C3H, Mice, Inbred C57BL, Nitrates, Oxidoreductases, Receptors, Notch, Virulence Factors
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Targeting aurora kinases limits tumour growth through DNA damage-mediated senescence and blockade of NF-κB impairs this drug-induced senescence.
Liu Y, Hawkins OE, Su Y, Vilgelm AE, Sobolik T, Thu YM, Kantrow S, Splittgerber RC, Short S, Amiri KI, Ecsedy JA, Sosman JA, Kelley MC, Richmond A
(2013) EMBO Mol Med 5: 149-66
MeSH Terms: Animals, Antineoplastic Agents, Ataxia Telangiectasia Mutated Proteins, Aurora Kinases, Azepines, Benzazepines, Cell Cycle Proteins, Cell Line, Tumor, Cell Proliferation, Cellular Senescence, Checkpoint Kinase 2, DNA Damage, DNA-Binding Proteins, Humans, Melanoma, Experimental, Mice, Mice, Nude, NF-kappa B, Polyploidy, Protein Kinase Inhibitors, Protein-Serine-Threonine Kinases, Pyrimidines, Tumor Suppressor Protein p53, Tumor Suppressor Proteins, Xenograft Model Antitumor Assays
Added June 14, 2013
2 Communities
7 Members
0 Resources
25 MeSH Terms
Tolvaptan in patients with autosomal dominant polycystic kidney disease.
Torres VE, Chapman AB, Devuyst O, Gansevoort RT, Grantham JJ, Higashihara E, Perrone RD, Krasa HB, Ouyang J, Czerwiec FS, TEMPO 3:4 Trial Investigators
(2012) N Engl J Med 367: 2407-18
MeSH Terms: Adolescent, Adult, Antidiuretic Hormone Receptor Antagonists, Benzazepines, Double-Blind Method, Female, Glomerular Filtration Rate, Humans, Kidney, Male, Middle Aged, Organ Size, Polycystic Kidney, Autosomal Dominant, Sodium, Tolvaptan, Young Adult
Added February 26, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Prostaglandin E2-mediated attenuation of mesocortical dopaminergic pathway is critical for susceptibility to repeated social defeat stress in mice.
Tanaka K, Furuyashiki T, Kitaoka S, Senzai Y, Imoto Y, Segi-Nishida E, Deguchi Y, Breyer RM, Breyer MD, Narumiya S
(2012) J Neurosci 32: 4319-29
MeSH Terms: 3,4-Dihydroxyphenylacetic Acid, Analysis of Variance, Animals, Benzazepines, Calcium-Binding Proteins, Corticosterone, Cyclooxygenase 1, Cyclooxygenase 2, Cyclooxygenase Inhibitors, Dinoprostone, Disease Models, Animal, Disease Susceptibility, Dominance-Subordination, Dopamine, Dopamine Antagonists, Homovanillic Acid, Interpersonal Relations, Maze Learning, Membrane Proteins, Mice, Mice, Inbred C57BL, Mice, Inbred ICR, Mice, Knockout, Microfilament Proteins, Neural Pathways, Oxidopamine, Prefrontal Cortex, Pyrazoles, Receptors, Prostaglandin E, Signal Transduction, Stress, Psychological, Sulfonamides, Time Factors, Tyrosine 3-Monooxygenase, Ventral Tegmental Area
Added December 21, 2013
1 Communities
1 Members
0 Resources
35 MeSH Terms
Tolvaptan in autosomal dominant polycystic kidney disease: three years' experience.
Higashihara E, Torres VE, Chapman AB, Grantham JJ, Bae K, Watnick TJ, Horie S, Nutahara K, Ouyang J, Krasa HB, Czerwiec FS, TEMPOFormula and 156-05-002 Study Investigators
(2011) Clin J Am Soc Nephrol 6: 2499-507
MeSH Terms: Adolescent, Adult, Antidiuretic Hormone Receptor Antagonists, Benzazepines, Disease Progression, Female, Glomerular Filtration Rate, Hormone Antagonists, Humans, Japan, Kidney, Male, Middle Aged, North America, Polycystic Kidney, Autosomal Dominant, Prospective Studies, Time Factors, Tolvaptan, Treatment Outcome, Young Adult
Added August 7, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
Intrarenal dopamine attenuates deoxycorticosterone acetate/high salt-induced blood pressure elevation in part through activation of a medullary cyclooxygenase 2 pathway.
Yao B, Harris RC, Zhang MZ
(2009) Hypertension 54: 1077-83
MeSH Terms: Analysis of Variance, Animals, Benzazepines, Blood Pressure Determination, Blotting, Western, Cyclooxygenase 2, Desoxycorticosterone, Dinoprostone, Disease Models, Animal, Dopamine, Hypertension, Immunohistochemistry, Kidney Medulla, Mice, Mice, Knockout, Probability, Random Allocation, Sodium Chloride, Dietary
Added December 10, 2013
1 Communities
2 Members
0 Resources
18 MeSH Terms
Mechanisms underlying methamphetamine-induced dopamine transporter complex formation.
Hadlock GC, Baucum AJ, King JL, Horner KA, Cook GA, Gibb JW, Wilkins DG, Hanson GR, Fleckenstein AE
(2009) J Pharmacol Exp Ther 329: 169-74
MeSH Terms: Animals, Benzazepines, Blotting, Western, Data Interpretation, Statistical, Dopamine, Dopamine Antagonists, Dopamine D2 Receptor Antagonists, Dopamine Plasma Membrane Transport Proteins, Dopamine Uptake Inhibitors, In Vitro Techniques, Male, Methamphetamine, Neostriatum, Nucleus Accumbens, Oxidopamine, Rats, Rats, Sprague-Dawley, Receptors, Dopamine D1, Receptors, Dopamine D2, Salicylamides, Sympathectomy, Chemical, Synaptosomes
Added December 7, 2012
0 Communities
1 Members
0 Resources
22 MeSH Terms
Aurora kinase A inhibition leads to p73-dependent apoptosis in p53-deficient cancer cells.
Dar AA, Belkhiri A, Ecsedy J, Zaika A, El-Rifai W
(2008) Cancer Res 68: 8998-9004
MeSH Terms: Apoptosis, Aurora Kinase A, Aurora Kinases, Benzazepines, Blotting, Western, Cell Line, Tumor, DNA-Binding Proteins, Humans, In Situ Nick-End Labeling, Nuclear Proteins, Phosphorylation, Protein Kinase Inhibitors, Protein-Serine-Threonine Kinases, Transcription, Genetic, Tumor Protein p73, Tumor Suppressor Protein p53, Tumor Suppressor Proteins
Added March 20, 2014
0 Communities
2 Members
0 Resources
17 MeSH Terms
Spatiotemporal pattern of striatal ERK1/2 phosphorylation in a rat model of L-DOPA-induced dyskinesia and the role of dopamine D1 receptors.
Westin JE, Vercammen L, Strome EM, Konradi C, Cenci MA
(2007) Biol Psychiatry 62: 800-10
MeSH Terms: Animals, Benzazepines, Cell Count, Denervation, Dopamine Agents, Dopamine Antagonists, Dynorphins, Dyskinesia, Drug-Induced, Enkephalins, Enzyme Activation, Female, Fluorescent Antibody Technique, Immunohistochemistry, In Situ Hybridization, Levodopa, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, Neostriatum, Neurons, Efferent, Phosphorylation, Rats, Rats, Sprague-Dawley, Receptors, Dopamine D1, Receptors, Dopamine D2
Added May 27, 2014
0 Communities
1 Members
0 Resources
24 MeSH Terms