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Results: 1 to 10 of 551

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Functional Properties of Helicobacter pylori VacA Toxin m1 and m2 Variants.
Caston RR, Sierra JC, Foegeding NJ, Truelock MD, Campbell AM, Frick-Cheng AE, Bimczok D, Wilson KT, McClain MS, Cover TL
(2020) Infect Immun 88:
MeSH Terms: Amino Acid Sequence, Bacterial Proteins, Bacterial Toxins, Gene Expression Regulation, Bacterial, Genetic Variation, Helicobacter Infections, Helicobacter pylori, Humans, Protein Domains, Protein Multimerization, Protein Transport, Vacuoles
Added April 15, 2020
0 Communities
1 Members
0 Resources
12 MeSH Terms
Symmetrically substituted dichlorophenes inhibit -acyl-phosphatidylethanolamine phospholipase D.
Aggarwal G, Zarrow JE, Mashhadi Z, Flynn CR, Vinson P, Weaver CD, Davies SS
(2020) J Biol Chem 295: 7289-7300
MeSH Terms: Animals, Bacterial Proteins, Bithionol, Dichlorophen, Enzyme Inhibitors, HEK293 Cells, Hexachlorophene, Humans, Mice, Phospholipase D, Quinazolines, Streptomyces, Sulfonamides
Added August 18, 2020
0 Communities
1 Members
0 Resources
13 MeSH Terms
Bacterial CagA protein compromises tumor suppressor mechanisms in gastric epithelial cells.
Palrasu M, Zaika E, El-Rifai W, Garcia-Buitrago M, Piazuelo MB, Wilson KT, Peek RM, Zaika AI
(2020) J Clin Invest 130: 2422-2434
MeSH Terms: Antigens, Bacterial, Apoptosis Regulatory Proteins, Bacterial Proteins, Epithelial Cells, Gastric Mucosa, HCT116 Cells, Helicobacter pylori, Humans, Neoplasm Proteins, Proteolysis, Stomach Neoplasms, Ubiquitination, X-Linked Inhibitor of Apoptosis Protein
Added April 7, 2020
0 Communities
1 Members
0 Resources
13 MeSH Terms
infection damages colonic stem cells via TcdB, impairing epithelial repair and recovery from disease.
Mileto SJ, Jardé T, Childress KO, Jensen JL, Rogers AP, Kerr G, Hutton ML, Sheedlo MJ, Bloch SC, Shupe JA, Horvay K, Flores T, Engel R, Wilkins S, McMurrick PJ, Lacy DB, Abud HE, Lyras D
(2020) Proc Natl Acad Sci U S A 117: 8064-8073
MeSH Terms: Animals, Bacterial Proteins, Bacterial Toxins, Cells, Cultured, Clostridioides difficile, Clostridium Infections, Colon, Disease Models, Animal, Female, Frizzled Receptors, Humans, Intestinal Mucosa, Mice, Organoids, Primary Cell Culture, Recombinant Proteins, Stem Cells
Added March 24, 2020
0 Communities
1 Members
0 Resources
17 MeSH Terms
Specificity and affinity of the N-terminal residues in staphylocoagulase in binding to prothrombin.
Maddur AA, Kroh HK, Aschenbrenner ME, Gibson BHY, Panizzi P, Sheehan JH, Meiler J, Bock PE, Verhamme IM
(2020) J Biol Chem 295: 5614-5625
MeSH Terms: Bacterial Proteins, Binding Sites, Coagulase, Humans, Models, Molecular, Protein Binding, Prothrombin, Staphylococcal Infections, Staphylococcus aureus, Substrate Specificity
Added March 21, 2020
0 Communities
1 Members
0 Resources
10 MeSH Terms
Applications of stable isotope-based metabolomics and fluxomics toward synthetic biology of cyanobacteria.
Babele PK, Young JD
(2020) Wiley Interdiscip Rev Syst Biol Med 12: e1472
MeSH Terms: Bacterial Proteins, Cyanobacteria, Gas Chromatography-Mass Spectrometry, Isotope Labeling, Metabolome, Metabolomics, Nitrogen, Phosphoenolpyruvate Carboxylase, Photosynthesis
Added March 5, 2020
0 Communities
1 Members
0 Resources
9 MeSH Terms
Structural insights into the transition of Clostridioides difficile binary toxin from prepore to pore.
Anderson DM, Sheedlo MJ, Jensen JL, Lacy DB
(2020) Nat Microbiol 5: 102-107
MeSH Terms: ADP Ribose Transferases, Bacterial Proteins, Bacterial Toxins, Caco-2 Cells, Cryoelectron Microscopy, Humans, Models, Molecular, Polysaccharides, Pore Forming Cytotoxic Proteins, Protein Binding, Protein Domains, Protein Multimerization, Receptors, LDL
Added March 24, 2020
0 Communities
1 Members
0 Resources
13 MeSH Terms
Bacterial Energetic Requirements for Helicobacter pylori Cag Type IV Secretion System-Dependent Alterations in Gastric Epithelial Cells.
Lin AS, Dooyema SDR, Frick-Cheng AE, Harvey ML, Suarez G, Loh JT, McDonald WH, McClain MS, Peek RM, Cover TL
(2020) Infect Immun 88:
MeSH Terms: Antigens, Bacterial, Bacterial Proteins, Biological Transport, DNA, Bacterial, Epithelial Cells, Helicobacter pylori, Humans, Interleukin-8, Lipopolysaccharides, NF-kappa B, Peptidoglycan, Toll-Like Receptor 9, Type IV Secretion Systems, Virulence Factors
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Staphylococcus aureus Infects Osteoclasts and Replicates Intracellularly.
Krauss JL, Roper PM, Ballard A, Shih CC, Fitzpatrick JAJ, Cassat JE, Ng PY, Pavlos NJ, Veis DJ
(2019) mBio 10:
MeSH Terms: Animals, Bacterial Proteins, Cell Differentiation, Cells, Cultured, Female, Macrophages, Male, Mice, Osteoblasts, Osteoclasts, Osteomyelitis, Phagosomes, RANK Ligand, Staphylococcus aureus
Added March 25, 2020
0 Communities
1 Members
0 Resources
14 MeSH Terms
A unified structural model of the mammalian translocator protein (TSPO).
Xia Y, Ledwitch K, Kuenze G, Duran A, Li J, Sanders CR, Manning C, Meiler J
(2019) J Biomol NMR 73: 347-364
MeSH Terms: Animals, Bacterial Proteins, Ligands, Mammals, Mice, Mitochondrial Membrane Transport Proteins, Mitochondrial Permeability Transition Pore, Models, Molecular, Molecular Imaging, Nuclear Magnetic Resonance, Biomolecular, Protein Binding, Protein Conformation, Receptors, GABA
Added March 21, 2020
0 Communities
1 Members
0 Resources
13 MeSH Terms