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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 16

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Protective Role of Spermidine in Colitis and Colon Carcinogenesis.
Gobert AP, Latour YL, Asim M, Barry DP, Allaman MM, Finley JL, Smith TM, McNamara KM, Singh K, Sierra JC, Delgado AG, Luis PB, Schneider C, Washington MK, Piazuelo MB, Zhao S, Coburn LA, Wilson KT
(2022) Gastroenterology 162: 813-827.e8
MeSH Terms: Adenomatous Polyposis Coli Protein, Animals, Azoxymethane, Carcinogenesis, Colitis, Colitis, Ulcerative, Colon, Colonic Neoplasms, Dextran Sulfate, Gastrointestinal Microbiome, Gene Expression Regulation, Humans, Intestinal Mucosa, Male, Mice, Oxidoreductases Acting on CH-NH Group Donors, Precancerous Conditions, Protective Factors, RNA, Messenger, Severity of Illness Index, Spermidine, Weight Loss, alpha-Defensins
Added November 18, 2021
0 Communities
1 Members
0 Resources
23 MeSH Terms
CCL11 exacerbates colitis and inflammation-associated colon tumorigenesis.
Polosukhina D, Singh K, Asim M, Barry DP, Allaman MM, Hardbower DM, Piazuelo MB, Washington MK, Gobert AP, Wilson KT, Coburn LA
(2021) Oncogene 40: 6540-6546
MeSH Terms: Animals, Azoxymethane, Carcinogenesis, Carcinogens, Chemokine CCL11, Colitis, Colitis-Associated Neoplasms, Epithelial Cells, Mice, Mice, Knockout
Added October 10, 2021
0 Communities
1 Members
0 Resources
10 MeSH Terms
Colonic Epithelial-Derived Selenoprotein P Is the Source for Antioxidant-Mediated Protection in Colitis-Associated Cancer.
Short SP, Pilat JM, Barrett CW, Reddy VK, Haberman Y, Hendren JR, Marsh BJ, Keating CE, Motley AK, Hill KE, Zemper AE, Washington MK, Shi C, Chen X, Wilson KT, Hyams JS, Denson LA, Burk RF, Rosen MJ, Williams CS
(2021) Gastroenterology 160: 1694-1708.e3
MeSH Terms: Adolescent, Animals, Azoxymethane, Case-Control Studies, Cell Transformation, Neoplastic, Child, Child, Preschool, Colitis, Colitis, Ulcerative, Colitis-Associated Neoplasms, Colon, DNA Damage, Dextran Sulfate, Disease Models, Animal, Female, Genomic Instability, Humans, Intestinal Mucosa, Liver, Male, Mice, Knockout, Myeloid Cells, Oxidative Stress, Selenoprotein P
Added March 11, 2021
0 Communities
2 Members
0 Resources
24 MeSH Terms
Identification and Characterization of Unique Neutralizing Antibodies to Mouse EGF Receptor.
Jae Huh W, Niitsu H, Carney B, McKinley ET, Houghton JL, Coffey RJ
(2020) Gastroenterology 158: 1500-1502
MeSH Terms: Animals, Antibodies, Monoclonal, Humanized, Antibodies, Neutralizing, Azoxymethane, Carcinogens, Cells, Cultured, Colonic Neoplasms, Dextran Sulfate, Disease Models, Animal, ErbB Receptors, Gastritis, Hypertrophic, Genes, Reporter, Hepatocytes, Humans, Mice, Mice, Transgenic, Primary Cell Culture
Added January 31, 2020
1 Communities
1 Members
0 Resources
17 MeSH Terms
Loss of solute carrier family 7 member 2 exacerbates inflammation-associated colon tumorigenesis.
Coburn LA, Singh K, Asim M, Barry DP, Allaman MM, Al-Greene NT, Hardbower DM, Polosukhina D, Williams CS, Delgado AG, Piazuelo MB, Washington MK, Gobert AP, Wilson KT
(2019) Oncogene 38: 1067-1079
MeSH Terms: Amino Acid Transport Systems, Basic, Animals, Azoxymethane, Cell Line, Tumor, Cell Transformation, Neoplastic, Colonic Neoplasms, Inflammation, Inflammatory Bowel Diseases, Mice, Mice, Knockout, Neoplasm Proteins
Added September 12, 2018
0 Communities
3 Members
0 Resources
11 MeSH Terms
Ornithine Decarboxylase in Macrophages Exacerbates Colitis and Promotes Colitis-Associated Colon Carcinogenesis by Impairing M1 Immune Responses.
Singh K, Coburn LA, Asim M, Barry DP, Allaman MM, Shi C, Washington MK, Luis PB, Schneider C, Delgado AG, Piazuelo MB, Cleveland JL, Gobert AP, Wilson KT
(2018) Cancer Res 78: 4303-4315
MeSH Terms: Animals, Azoxymethane, Carcinogenesis, Colitis, Ulcerative, Colon, Colonic Neoplasms, Cytokines, Dextran Sulfate, Inflammation, Macrophage Activation, Macrophages, Male, Mice, Ornithine Decarboxylase, Transcription, Genetic, Up-Regulation
Added June 15, 2018
0 Communities
2 Members
0 Resources
16 MeSH Terms
Four jointed box 1 promotes angiogenesis and is associated with poor patient survival in colorectal carcinoma.
Al-Greene NT, Means AL, Lu P, Jiang A, Schmidt CR, Chakravarthy AB, Merchant NB, Washington MK, Zhang B, Shyr Y, Deane NG, Beauchamp RD
(2013) PLoS One 8: e69660
MeSH Terms: Animals, Azoxymethane, Cell Line, Cell Line, Tumor, Cell Proliferation, Colorectal Neoplasms, Dextran Sulfate, Female, Humans, In Vitro Techniques, Mice, Mice, Nude, Neovascularization, Pathologic, Nerve Tissue Proteins
Added August 22, 2013
1 Communities
8 Members
0 Resources
14 MeSH Terms
Dietary selenium deficiency exacerbates DSS-induced epithelial injury and AOM/DSS-induced tumorigenesis.
Barrett CW, Singh K, Motley AK, Lintel MK, Matafonova E, Bradley AM, Ning W, Poindexter SV, Parang B, Reddy VK, Chaturvedi R, Fingleton BM, Washington MK, Wilson KT, Davies SS, Hill KE, Burk RF, Williams CS
(2013) PLoS One 8: e67845
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Animals, Azoxymethane, Carcinogenesis, Colitis, Colonic Neoplasms, DNA Damage, Deoxyguanosine, Dextran Sulfate, Diet, Epidermal Growth Factor, Gene Expression Regulation, Inflammation, Mice, Mice, Inbred C57BL, Selenium, Signal Transduction, Transforming Growth Factor beta, Weight Loss
Added March 5, 2014
3 Communities
8 Members
0 Resources
19 MeSH Terms
Mutant p53 prolongs NF-κB activation and promotes chronic inflammation and inflammation-associated colorectal cancer.
Cooks T, Pateras IS, Tarcic O, Solomon H, Schetter AJ, Wilder S, Lozano G, Pikarsky E, Forshew T, Rosenfeld N, Rozenfeld N, Harpaz N, Itzkowitz S, Harris CC, Rotter V, Gorgoulis VG, Oren M
(2013) Cancer Cell 23: 634-46
MeSH Terms: Animals, Azoxymethane, Colitis, Colon, Colorectal Neoplasms, DNA Damage, Dextran Sulfate, Genetic Predisposition to Disease, Histones, Humans, Mice, Mice, Inbred C57BL, NF-kappa B, Nitric Oxide Synthase Type II, Protein Isoforms, Tumor Necrosis Factor-alpha, Tumor Suppressor Protein p53
Added July 31, 2013
0 Communities
0 Members
0 Resources
17 MeSH Terms
MTGR1 is required for tumorigenesis in the murine AOM/DSS colitis-associated carcinoma model.
Barrett CW, Fingleton B, Williams A, Ning W, Fischer MA, Washington MK, Chaturvedi R, Wilson KT, Hiebert SW, Williams CS
(2011) Cancer Res 71: 1302-12
MeSH Terms: Animals, Azoxymethane, Carcinoma, Cell Transformation, Neoplastic, Colitis, Colonic Neoplasms, Dextran Sulfate, Disease Models, Animal, Disease Progression, Gene Expression Regulation, Neoplastic, HCT116 Cells, Humans, Mice, Mice, Inbred C57BL, Mice, Knockout, Repressor Proteins
Added July 28, 2012
3 Communities
6 Members
0 Resources
16 MeSH Terms