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6 MeSH Terms
Total RNA Sequencing of Rett Syndrome Autopsy Samples Identifies the M Muscarinic Receptor as a Novel Therapeutic Target.Gogliotti RG, Fisher NM, Stansley BJ, Jones CK, Lindsley CW, Conn PJ, Niswender CM
(2018)
J Pharmacol Exp Ther 365: 291-300
MeSH Terms: Animals, Autopsy, Cerebellum, Humans, Mice, Molecular Targeted Therapy, Motor Cortex, Receptor, Muscarinic M4, Rett Syndrome, Sequence Analysis, RNAAdded March 3, 2020 0 Communities
2 Members
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MeSH Terms
mGlu potentiation rescues cognitive, social, and respiratory phenotypes in a mouse model of Rett syndrome.Gogliotti RG, Senter RK, Fisher NM, Adams J, Zamorano R, Walker AG, Blobaum AL, Engers DW, Hopkins CR, Daniels JS, Jones CK, Lindsley CW, Xiang Z, Conn PJ, Niswender CM
(2017)
Sci Transl Med 9:
MeSH Terms: Animals, Apnea, Autopsy, CA1 Region, Hippocampal, Cognition, Disease Models, Animal, Dose-Response Relationship, Drug, Female, Humans, Long-Term Potentiation, Male, Memory, Methyl-CpG-Binding Protein 2, Mice, Motor Cortex, Neuronal Plasticity, Phenotype, Picolinic Acids, RNA, Messenger, Rats, Sprague-Dawley, Receptors, Metabotropic Glutamate, Respiration, Rett Syndrome, Social Behavior, Transcription, GeneticAdded March 3, 2020 0 Communities
2 Members
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MeSH Terms
mGlu5 positive allosteric modulation normalizes synaptic plasticity defects and motor phenotypes in a mouse model of Rett syndrome.Gogliotti RG, Senter RK, Rook JM, Ghoshal A, Zamorano R, Malosh C, Stauffer SR, Bridges TM, Bartolome JM, Daniels JS, Jones CK, Lindsley CW, Conn PJ, Niswender CM
(2016)
Hum Mol Genet 25: 1990-2004
MeSH Terms: Adult, Allosteric Regulation, Animals, Autistic Disorder, Autopsy, Disease Models, Animal, Female, Gene Expression Regulation, Hippocampus, Humans, Male, Methyl-CpG-Binding Protein 2, Mice, Mice, Knockout, Motor Cortex, Neuronal Plasticity, Pyrazoles, Pyrimidinones, Receptor, Metabotropic Glutamate 5, Rett Syndrome, Seizures, Signal Transduction, Young AdultAdded April 6, 2017 0 Communities
4 Members
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23 MeSH Terms
A Mutual Self- and Informant-Report of Cognitive Complaint Correlates with Neuropathological Outcomes in Mild Cognitive Impairment.Gifford KA, Liu D, Hohman TJ, Xu M, Han X, Romano RR, Fritzsche LR, Abel T, Jefferson AL
(2015)
PLoS One 10: e0141831
MeSH Terms: Aged, Aged, 80 and over, Aging, Alzheimer Disease, Apolipoprotein E4, Autopsy, Brain, Cognition, Cognitive Dysfunction, Female, Humans, Male, Nervous System Diseases, Neurofibrillary Tangles, Neuropsychological Tests, Plaque, AmyloidAdded February 22, 2016 0 Communities
2 Members
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16 MeSH Terms
Pathological changes long after liver transplantation in a familial amyloidotic polyneuropathy patient.Obayashi K, Ueda M, Oshima T, Kawahara S, Misumi Y, Yamashita T, Jono H, Yazaki M, Kametani F, Ikeda S, Ohya Y, Asonuma K, Inomata Y, Ando Y
(2012)
BMJ Case Rep 2012:
MeSH Terms: Adult, Amyloid Neuropathies, Familial, Autopsy, Brain Chemistry, Fatal Outcome, Gastrointestinal Tract, Heart Ventricles, Humans, Kidney, Liver, Liver Transplantation, Lung, Male, Pancreas, Peripheral Nerves, Prealbumin, Thyroid Gland, TongueAdded February 11, 2015 0 Communities
1 Members
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18 MeSH Terms
Are respiratory complications common causes of death in inflammatory myopathies? An autopsy study.Maldonado F, Patel RR, Iyer VN, Yi ES, Ryu JH
(2012)
Respirology 17: 455-60
MeSH Terms: Adolescent, Adult, Aged, Aged, 80 and over, Autopsy, Cardiovascular Diseases, Cause of Death, Dermatomyositis, Disease Progression, Female, Humans, Male, Middle Aged, Polymyositis, Respiratory Tract Diseases, Retrospective Studies, Young AdultAdded February 1, 2016 0 Communities
1 Members
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17 MeSH Terms
Bipolar disorder type 1 and schizophrenia are accompanied by decreased density of parvalbumin- and somatostatin-positive interneurons in the parahippocampal region.Wang AY, Lohmann KM, Yang CK, Zimmerman EI, Pantazopoulos H, Herring N, Berretta S, Heckers S, Konradi C
(2011)
Acta Neuropathol 122: 615-26
MeSH Terms: Adolescent, Adult, Aged, Aged, 80 and over, Autopsy, Bipolar Disorder, Calbindins, Case-Control Studies, Cell Count, Entorhinal Cortex, Female, Hippocampus, Humans, Interneurons, Male, Middle Aged, Nerve Net, Parahippocampal Gyrus, Parvalbumins, S100 Calcium Binding Protein G, Schizophrenia, Somatostatin, Young AdultAdded May 27, 2014 0 Communities
2 Members
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23 MeSH Terms
Analyzing schizophrenia by DNA microarrays.Horváth S, Janka Z, Mirnics K
(2011)
Biol Psychiatry 69: 157-62
MeSH Terms: Autopsy, Brain, Brain Chemistry, Gene Expression Profiling, Humans, Nerve Tissue Proteins, Neuropsychiatry, Oligonucleotide Array Sequence Analysis, Postmortem Changes, SchizophreniaAdded May 19, 2014 0 Communities
1 Members
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10 MeSH Terms
Perceptions, knowledge, incentives, and barriers of brain donation among African American elders enrolled in an Alzheimer's research program.Lambe S, Cantwell N, Islam F, Horvath K, Jefferson AL
(2011)
Gerontologist 51: 28-38
MeSH Terms: African Americans, Aged, Aged, 80 and over, Alzheimer Disease, Autopsy, Biomedical Research, Boston, Brain, Educational Status, Female, Focus Groups, Health Knowledge, Attitudes, Practice, Humans, Male, Middle Aged, Qualitative Research, Surveys and Questionnaires, Tissue DonorsAdded March 26, 2019 0 Communities
1 Members
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MeSH Terms