mPGES1-Dependent Prostaglandin E (PGE) Controls Antigen-Specific Th17 and Th1 Responses by Regulating T Autocrine and Paracrine PGE Production.
Maseda D, Johnson EM, Nyhoff LE, Baron B, Kojima F, Wilhelm AJ, Ward MR, Woodward JG, Brand DD, Crofford LJ
(2018) J Immunol 200
: 725-736MeSH Terms: Animals, Autocrine Communication, Dinoprostone, Epitopes, T-Lymphocyte, Gene Expression Regulation, Immunization, Immunomodulation, Lymphocyte Activation, Mice, Paracrine Communication, Phenotype, Prostaglandin-E Synthases, Receptors, Prostaglandin E, EP2 Subtype, Receptors, Prostaglandin E, EP4 Subtype, Th1 Cells, Th17 CellsAdded March 25, 2020
BET bromodomain inhibitors suppress EWS-FLI1-dependent transcription and the IGF1 autocrine mechanism in Ewing sarcoma.
Loganathan SN, Tang N, Fleming JT, Ma Y, Guo Y, Borinstein SC, Chiang C, Wang J
(2016) Oncotarget 7
: 43504-43517MeSH Terms: Animals, Antineoplastic Agents, Autocrine Communication, Azepines, Bone Neoplasms, Cell Line, Tumor, Cell Proliferation, Cell Survival, Epigenesis, Genetic, Female, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Humans, Insulin-Like Growth Factor I, Mice, Mice, Nude, NIH 3T3 Cells, Oncogene Proteins, Fusion, Proteins, Proto-Oncogene Protein c-fli-1, Proto-Oncogene Proteins c-akt, RNA-Binding Protein EWS, Receptor, IGF Type 1, Receptors, Somatomedin, Sarcoma, Ewing, Signal Transduction, Transcription, Genetic, Triazoles, Xenograft Model Antitumor AssaysAdded November 19, 2016
29 MeSH Terms
Loss of the polarity protein PAR3 activates STAT3 signaling via an atypical protein kinase C (aPKC)/NF-κB/interleukin-6 (IL-6) axis in mouse mammary cells.
Guyer RA, Macara IG
(2015) J Biol Chem 290
: 8457-68MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Autocrine Communication, Cell Adhesion Molecules, Cell Cycle Proteins, Cells, Cultured, Cytokine Receptor gp130, Enzyme Activation, Epithelial Cells, Female, Interleukin-6, Mammary Glands, Animal, Mice, Inbred C3H, NF-kappa B, Phosphorylation, Protein Kinase C, Protein Processing, Post-Translational, STAT3 Transcription Factor, Signal TransductionAdded April 10, 2018
19 MeSH Terms
Autocrine VEGF/VEGFR1 signaling in a subpopulation of cells associates with aggressive osteosarcoma.
Ohba T, Cates JM, Cole HA, Slosky DA, Haro H, Ando T, Schwartz HS, Schoenecker JG
(2014) Mol Cancer Res 12
: 1100-11MeSH Terms: Animals, Autocrine Communication, Bone Neoplasms, Cell Line, Tumor, Cell Proliferation, Humans, Mice, Mice, Inbred BALB C, Neovascularization, Pathologic, Osteolysis, Osteosarcoma, Signal Transduction, Vascular Endothelial Growth Factor A, Vascular Endothelial Growth Factor Receptor-1Added May 28, 2014
14 MeSH Terms
Bves and NDRG4 regulate directional epicardial cell migration through autocrine extracellular matrix deposition.
Benesh EC, Miller PM, Pfaltzgraff ER, Grega-Larson NE, Hager HA, Sung BH, Qu X, Baldwin HS, Weaver AM, Bader DM
(2013) Mol Biol Cell 24
: 3496-510MeSH Terms: Animals, Autocrine Communication, COS Cells, Cell Adhesion Molecules, Cell Membrane, Cell Movement, Chlorocebus aethiops, Embryo, Mammalian, Endosomes, Extracellular Matrix, Fibronectins, Gene Expression Regulation, Developmental, Mice, Mice, Inbred C57BL, Muscle Proteins, Nerve Tissue Proteins, Pericardium, Primary Cell Culture, Signal Transduction, Transport VesiclesAdded March 7, 2014
20 MeSH Terms
Smad7 inhibits autocrine expression of TGF-β2 in intestinal epithelial cells in baboon necrotizing enterocolitis.
Namachivayam K, Blanco CL, MohanKumar K, Jagadeeswaran R, Vasquez M, McGill-Vargas L, Garzon SA, Jain SK, Gill RK, Freitag NE, Weitkamp JH, Seidner SR, Maheshwari A
(2013) Am J Physiol Gastrointest Liver Physiol 304
: G167-80MeSH Terms: Animals, Autocrine Communication, Blotting, Western, Cell Line, Colon, DNA-Binding Proteins, Disease Models, Animal, Down-Regulation, Enterocolitis, Necrotizing, Gestational Age, Humans, Immunohistochemistry, Intestinal Mucosa, Intracellular Signaling Peptides and Proteins, Papio anubis, Papio cynocephalus, Premature Birth, Proto-Oncogene Proteins, Reverse Transcriptase Polymerase Chain Reaction, Smad7 Protein, Transfection, Transforming Growth Factor beta2Added February 27, 2014
22 MeSH Terms
Connective tissue growth factor acts within both endothelial cells and beta cells to promote proliferation of developing beta cells.
Guney MA, Petersen CP, Boustani A, Duncan MR, Gunasekaran U, Menon R, Warfield C, Grotendorst GR, Means AL, Economides AN, Gannon M
(2011) Proc Natl Acad Sci U S A 108
: 15242-7MeSH Terms: Animals, Autocrine Communication, Cell Lineage, Cell Proliferation, Cell Size, Connective Tissue Growth Factor, Embryonic Development, Endothelial Cells, Insulin-Secreting Cells, Mice, Models, Biological, Morphogenesis, RatsAdded January 6, 2014
13 MeSH Terms
Induction of podocyte-derived VEGF ameliorates podocyte injury and subsequent abnormal glomerular development caused by puromycin aminonucleoside.
Ma J, Matsusaka T, Yang HC, Zhong J, Takagi N, Fogo AB, Kon V, Ichikawa I
(2011) Pediatr Res 70
: 83-9MeSH Terms: Actinin, Animals, Animals, Newborn, Apoptosis, Autocrine Communication, Caspase 3, Cells, Cultured, Desmin, Disease Models, Animal, Doxycycline, Glomerulonephritis, Humans, Intracellular Signaling Peptides and Proteins, Kidney Glomerulus, Membrane Proteins, Mice, Mice, Inbred C57BL, Mice, Transgenic, Microfilament Proteins, Podocytes, Puromycin Aminonucleoside, Response Elements, Vascular Endothelial Growth Factor A, bcl-2-Associated X Protein, bcl-X ProteinAdded January 25, 2012
25 MeSH Terms
Loss of annexin A1 disrupts normal prostate glandular structure by inducing autocrine IL-6 signaling.
Inokuchi J, Lau A, Tyson DR, Ornstein DK
(2009) Carcinogenesis 30
: 1082-8MeSH Terms: Annexin A1, Autocrine Communication, Cell Line, Cell Transformation, Neoplastic, Epithelial Cells, Humans, Interleukin-6, Male, Prostate, Prostatic Neoplasms, Up-RegulationAdded February 27, 2013
11 MeSH Terms
Regulation of T-cell function by endogenously produced angiotensin II.
Hoch NE, Guzik TJ, Chen W, Deans T, Maalouf SA, Gratze P, Weyand C, Harrison DG
(2009) Am J Physiol Regul Integr Comp Physiol 296
: R208-16MeSH Terms: Adoptive Transfer, Angiotensin II, Angiotensin II Type 1 Receptor Blockers, Angiotensin II Type 2 Receptor Blockers, Angiotensinogen, Animals, Autocrine Communication, Blood Pressure, Catalase, Cells, Cultured, Homeodomain Proteins, Imidazoles, Infusion Pumps, Implantable, Losartan, Lymphocyte Activation, Mice, Mice, Inbred C57BL, Mice, Knockout, NADPH Oxidases, Peptidyl-Dipeptidase A, Polyethylene Glycols, Pyridines, Receptor, Angiotensin, Type 1, Receptor, Angiotensin, Type 2, Renin, Renin-Angiotensin System, Superoxide Dismutase, Superoxides, T-Lymphocytes, Time Factors, Tumor Necrosis Factor-alphaAdded December 10, 2013
31 MeSH Terms