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Cobicistat Versus Ritonavir: Similar Pharmacokinetic Enhancers But Some Important Differences.
Tseng A, Hughes CA, Wu J, Seet J, Phillips EJ
(2017) Ann Pharmacother 51: 1008-1022
MeSH Terms: Anti-HIV Agents, Atazanavir Sulfate, Cobicistat, Darunavir, Drug Interactions, HIV Infections, Humans, Quinolones, Ritonavir
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Atazanavir improves cardiometabolic measures but not vascular function in patients with long-standing type 1 diabetes mellitus.
Milian J, Goldfine AB, Zuflacht JP, Parmer C, Beckman JA
(2015) Acta Diabetol 52: 709-15
MeSH Terms: Adult, Antioxidants, Atazanavir Sulfate, Atherosclerosis, Bilirubin, Blood Pressure, Cardiovascular System, Cholesterol, LDL, Diabetes Mellitus, Type 1, Endothelium, Vascular, Female, Humans, Male, Middle Aged, Oxidative Stress, Risk Factors, Vasodilation
Added January 15, 2016
0 Communities
1 Members
0 Resources
17 MeSH Terms
Efficacy and tolerability of 3 nonnucleoside reverse transcriptase inhibitor-sparing antiretroviral regimens for treatment-naive volunteers infected with HIV-1: a randomized, controlled equivalence trial.
Lennox JL, Landovitz RJ, Ribaudo HJ, Ofotokun I, Na LH, Godfrey C, Kuritzkes DR, Sagar M, Brown TT, Cohn SE, McComsey GA, Aweeka F, Fichtenbaum CJ, Presti RM, Koletar SL, Haas DW, Patterson KB, Benson CA, Baugh BP, Leavitt RY, Rooney JF, Seekins D, Currier JS, ACTG A5257 Team
(2014) Ann Intern Med 161: 461-71
MeSH Terms: Adenine, Adult, Atazanavir Sulfate, Darunavir, Deoxycytidine, Drug Combinations, Drug Therapy, Combination, Emtricitabine, Female, HIV Infections, HIV Protease Inhibitors, HIV-1, Humans, Male, Oligopeptides, Organophosphonates, Pyridines, RNA, Viral, Reverse Transcriptase Inhibitors, Sulfonamides, Tenofovir, Therapeutic Equivalency, Viral Load
Added March 13, 2015
0 Communities
1 Members
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23 MeSH Terms
Genomewide association study of atazanavir pharmacokinetics and hyperbilirubinemia in AIDS Clinical Trials Group protocol A5202.
Johnson DH, Venuto C, Ritchie MD, Morse GD, Daar ES, McLaren PJ, Haas DW
(2014) Pharmacogenet Genomics 24: 195-203
MeSH Terms: Acquired Immunodeficiency Syndrome, Adult, Antiretroviral Therapy, Highly Active, Atazanavir Sulfate, Bilirubin, Female, Genome-Wide Association Study, Glucuronosyltransferase, HIV Protease Inhibitors, Humans, Hyperbilirubinemia, Male, Middle Aged, Multivariate Analysis, Oligopeptides, Polymorphism, Single Nucleotide, Prospective Studies, Pyridines, Ritonavir
Added March 13, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms
Impact of UGT1A1 Gilbert variant on discontinuation of ritonavir-boosted atazanavir in AIDS Clinical Trials Group Study A5202.
Ribaudo HJ, Daar ES, Tierney C, Morse GD, Mollan K, Sax PE, Fischl MA, Collier AC, Haas DW, DS Clinical Trials Group
(2013) J Infect Dis 207: 420-5
MeSH Terms: Anti-HIV Agents, Antiretroviral Therapy, Highly Active, Atazanavir Sulfate, Bilirubin, Genetic Variation, Genotype, Glucuronosyltransferase, HIV Infections, HIV-1, Humans, Jaundice, Oligopeptides, Pyridines, Ritonavir
Added March 13, 2015
0 Communities
1 Members
0 Resources
14 MeSH Terms
Hepatotoxicity and gastrointestinal intolerance when healthy volunteers taking rifampin add twice-daily atazanavir and ritonavir.
Haas DW, Koletar SL, Laughlin L, Kendall MA, Suckow C, Gerber JG, Zolopa AR, Bertz R, Child MJ, Hosey L, Alston-Smith B, Acosta EP, A5213 StudyTeam
(2009) J Acquir Immune Defic Syndr 50: 290-3
MeSH Terms: Adult, Antitubercular Agents, Atazanavir Sulfate, Female, Gastrointestinal Tract, HIV Protease Inhibitors, Humans, Liver, Male, Oligopeptides, Pyridines, Rifampin, Ritonavir
Added March 13, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms
Effect of concomitantly administered rifampin on the pharmacokinetics and safety of atazanavir administered twice daily.
Acosta EP, Kendall MA, Gerber JG, Alston-Smith B, Koletar SL, Zolopa AR, Agarwala S, Child M, Bertz R, Hosey L, Haas DW
(2007) Antimicrob Agents Chemother 51: 3104-10
MeSH Terms: Adolescent, Adult, Anti-HIV Agents, Antitubercular Agents, Area Under Curve, Atazanavir Sulfate, Biotransformation, Drug Interactions, Female, HIV Infections, Half-Life, Humans, Male, Middle Aged, Oligopeptides, Pyridines, Rifampin, Tuberculosis
Added March 13, 2015
0 Communities
1 Members
0 Resources
18 MeSH Terms
The effects of HIV protease inhibitors atazanavir and lopinavir/ritonavir on insulin sensitivity in HIV-seronegative healthy adults.
Noor MA, Parker RA, O'Mara E, Grasela DM, Currie A, Hodder SL, Fiedorek FT, Haas DW
(2004) AIDS 18: 2137-44
MeSH Terms: Adult, Analysis of Variance, Atazanavir Sulfate, Cross-Over Studies, Double-Blind Method, Energy Metabolism, Fatty Acids, Nonesterified, Glycogen, HIV Protease Inhibitors, HIV Seronegativity, Humans, Insulin Resistance, Lipids, Lipodystrophy, Lopinavir, Oligopeptides, Pyridines, Pyrimidinones
Added March 13, 2015
0 Communities
1 Members
0 Resources
18 MeSH Terms
Therapy with atazanavir plus saquinavir in patients failing highly active antiretroviral therapy: a randomized comparative pilot trial.
Haas DW, Zala C, Schrader S, Piliero P, Jaeger H, Nunes D, Thiry A, Schnittman S, Sension M, Protocol AI424-009 Study Group
(2003) AIDS 17: 1339-49
MeSH Terms: Adult, Antiretroviral Therapy, Highly Active, Atazanavir Sulfate, CD4 Lymphocyte Count, Drug Administration Schedule, Drug Therapy, Combination, Female, HIV Infections, HIV-1, Humans, Lipids, Male, Oligopeptides, Pilot Projects, Protease Inhibitors, Pyridines, RNA, Viral, Ritonavir, Salvage Therapy, Saquinavir, Treatment Failure
Added March 13, 2015
0 Communities
1 Members
0 Resources
21 MeSH Terms