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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 12

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Axonal organization defects in the hippocampus of adult conditional BACE1 knockout mice.
Ou-Yang MH, Kurz JE, Nomura T, Popovic J, Rajapaksha TW, Dong H, Contractor A, Chetkovich DM, Tourtellotte WG, Vassar R
(2018) Sci Transl Med 10:
MeSH Terms: Aging, Amyloid Precursor Protein Secretases, Animals, Animals, Newborn, Apoptosis, Aspartic Acid Endopeptidases, Axons, Cognition, Epilepsy, Gene Deletion, Hippocampus, Long-Term Potentiation, Memory Disorders, Mice, Inbred C57BL, Mice, Knockout, Myelin Sheath, Neurogenesis, Phenotype, Substrate Specificity
Added April 2, 2019
0 Communities
1 Members
0 Resources
19 MeSH Terms
Differential proteomic and behavioral effects of long-term voluntary exercise in wild-type and APP-overexpressing transgenics.
Rao SK, Ross JM, Harrison FE, Bernardo A, Reiserer RS, Reiserer RS, Mobley JA, McDonald MP
(2015) Neurobiol Dis 78: 45-55
MeSH Terms: Alzheimer Disease, Amyloid Precursor Protein Secretases, Amyloid beta-Protein Precursor, Animals, Aspartic Acid Endopeptidases, Behavior, Animal, Hippocampus, Mice, Mice, Transgenic, Motor Activity, Presenilin-1, Proteomics, Spatial Memory
Added May 11, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms
Comparative analysis of Napsin A, alpha-methylacyl-coenzyme A racemase (AMACR, P504S), and hepatocyte nuclear factor 1 beta as diagnostic markers of ovarian clear cell carcinoma: an immunohistochemical study of 279 ovarian tumours.
Fadare O, Zhao C, Khabele D, Parkash V, Quick CM, Gwin K, Desouki MM
(2015) Pathology 47: 105-11
MeSH Terms: Adenocarcinoma, Clear Cell, Aspartic Acid Endopeptidases, Biomarkers, Tumor, Diagnosis, Differential, Female, Hepatocyte Nuclear Factor 1-beta, Humans, Immunohistochemistry, Neoplasm Grading, Ovarian Neoplasms, Racemases and Epimerases, Sensitivity and Specificity
Added February 19, 2015
0 Communities
1 Members
0 Resources
12 MeSH Terms
Identification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies.
Hayes MG, Urbanek M, Hivert MF, Armstrong LL, Morrison J, Guo C, Lowe LP, Scheftner DA, Pluzhnikov A, Levine DM, McHugh CP, Ackerman CM, Bouchard L, Brisson D, Layden BT, Mirel D, Doheny KF, Leya MV, Lown-Hecht RN, Dyer AR, Metzger BE, Reddy TE, Cox NJ, Lowe WL, HAPO Study Cooperative Research Group
(2013) Diabetes 62: 3282-91
MeSH Terms: Adolescent, Adult, Amyloid Precursor Protein Secretases, Aspartic Acid Endopeptidases, Blood Glucose, C-Peptide, Fasting, Female, Genome-Wide Association Study, Genotype, Glucose Tolerance Test, Humans, Pregnancy, Young Adult
Added February 22, 2016
0 Communities
1 Members
0 Resources
14 MeSH Terms
Inflammatory prostaglandin E2 signaling in a mouse model of Alzheimer disease.
Shi J, Wang Q, Johansson JU, Liang X, Woodling NS, Priyam P, Loui TM, Merchant M, Breyer RM, Montine TJ, Andreasson K
(2012) Ann Neurol 72: 788-98
MeSH Terms: Age Factors, Alzheimer Disease, Amyloid Precursor Protein Secretases, Amyloid beta-Peptides, Amyloid beta-Protein Precursor, Analysis of Variance, Animals, Animals, Newborn, Aspartic Acid Endopeptidases, Brain, Calcium-Binding Proteins, Cells, Cultured, Cognitive Dysfunction, DNA-Binding Proteins, Dinoprostone, Disease Models, Animal, Encephalitis, Female, Gene Expression Regulation, Glial Fibrillary Acidic Protein, Humans, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, Microfilament Proteins, Microtubule-Associated Proteins, Mutation, Neurons, Oxidative Stress, Peptide Fragments, Prostaglandin-Endoperoxide Synthases, RNA, Messenger, Receptors, Prostaglandin E, EP3 Subtype, Signal Transduction, Synaptosomal-Associated Protein 25, Vesicle-Associated Membrane Protein 2
Added December 21, 2013
2 Communities
1 Members
0 Resources
37 MeSH Terms
Diagnostic utility of PAX8, TTF-1 and napsin A for discriminating metastatic carcinoma from primary adenocarcinoma of the lung.
Ye J, Hameed O, Findeis-Hosey JJ, Fan L, Li F, McMahon LA, Yang Q, Wang HL, Xu H
(2012) Biotech Histochem 87: 30-4
MeSH Terms: Adenocarcinoma, Aspartic Acid Endopeptidases, Biomarkers, Tumor, DNA-Binding Proteins, Diagnosis, Differential, Humans, Immunohistochemistry, Lung Neoplasms, PAX8 Transcription Factor, Paired Box Transcription Factors, Transcription Factors
Added March 21, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
BMPR2 mutation alters the lung macrophage endothelin-1 cascade in a mouse model and patients with heritable pulmonary artery hypertension.
Talati M, West J, Blackwell TR, Loyd JE, Meyrick B
(2010) Am J Physiol Lung Cell Mol Physiol 299: L363-73
MeSH Terms: Adolescent, Adult, Aged, Animals, Aspartic Acid Endopeptidases, Bone Morphogenetic Protein Receptors, Type II, Endothelin-1, Endothelin-Converting Enzymes, Female, Gene Expression, Humans, Hypertension, Pulmonary, Macrophages, Macrophages, Alveolar, Male, Metalloendopeptidases, Mice, Mice, Mutant Strains, Microscopy, Confocal, Middle Aged, Mutation, Receptor, Endothelin A, Receptor, Endothelin B, Tissue Distribution, Young Adult
Added March 5, 2014
0 Communities
2 Members
0 Resources
25 MeSH Terms
Analysis of transmembrane domain mutants is consistent with sequential cleavage of Notch by gamma-secretase.
Chandu D, Huppert SS, Kopan R
(2006) J Neurochem 96: 228-35
MeSH Terms: Amyloid Precursor Protein Secretases, Aspartic Acid Endopeptidases, Cell Line, Cell Membrane, Cytosol, Endopeptidases, Humans, Hydrolysis, Immunoprecipitation, Isoenzymes, Leucine, Methionine, Mutation, Peptide Hydrolases, Protease Inhibitors, Receptor, Notch1
Added January 11, 2011
1 Communities
1 Members
0 Resources
16 MeSH Terms
Analysis of Notch function in presomitic mesoderm suggests a gamma-secretase-independent role for presenilins in somite differentiation.
Huppert SS, Ilagan MX, De Strooper B, Kopan R
(2005) Dev Cell 8: 677-88
MeSH Terms: Amyloid Precursor Protein Secretases, Animals, Aspartic Acid Endopeptidases, Body Patterning, Cell Differentiation, Endopeptidases, In Situ Hybridization, Membrane Proteins, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, Mutant Strains, Microscopy, Electron, Scanning, Phenotype, Presenilin-1, Presenilin-2, Receptor, Notch1, Receptor, Notch2, Receptors, Cell Surface, Somites, Transcription Factors
Added January 11, 2011
1 Communities
1 Members
0 Resources
21 MeSH Terms
Diarrhea-associated HIV-1 APIs potentiate muscarinic activation of Cl- secretion by T84 cells via prolongation of cytosolic Ca2+ signaling.
Rufo PA, Lin PW, Andrade A, Jiang L, Rameh L, Flexner C, Alper SL, Lencer WI
(2004) Am J Physiol Cell Physiol 286: C998-C1008
MeSH Terms: Adult, Aspartic Acid Endopeptidases, Calcium Signaling, Carbachol, Cell Line, Cell Membrane, Chlorides, Cytosol, Diarrhea, Drug Synergism, Electric Conductivity, HIV Infections, HIV-1, Humans, Intestinal Mucosa, Intracellular Membranes, Middle Aged, Muscarinic Agonists, Nelfinavir, Protease Inhibitors, Time Factors
Added December 10, 2018
0 Communities
1 Members
0 Resources
21 MeSH Terms