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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 8 of 8

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ARNT as a Novel Antifibrotic Target in CKD.
Haase VH
(2019) Am J Kidney Dis 73: 281-284
MeSH Terms: Aryl Hydrocarbon Receptor Nuclear Translocator, Humans, Hypoxia, Kidney Failure, Chronic, Transcription Factors
Added October 28, 2018
0 Communities
1 Members
0 Resources
5 MeSH Terms
The role of VHL in clear-cell renal cell carcinoma and its relation to targeted therapy.
Clark PE
(2009) Kidney Int 76: 939-45
MeSH Terms: Animals, Antibodies, Monoclonal, Antineoplastic Agents, Aryl Hydrocarbon Receptor Nuclear Translocator, Carcinoma, Renal Cell, Drug Design, Gene Expression Regulation, Neoplastic, Humans, Hypoxia-Inducible Factor 1, alpha Subunit, Kidney Neoplasms, Protein Kinase Inhibitors, Protein Kinases, Receptors, Vascular Endothelial Growth Factor, Signal Transduction, TOR Serine-Threonine Kinases, Translational Research, Biomedical, Treatment Outcome, Vascular Endothelial Growth Factor A, Von Hippel-Lindau Tumor Suppressor Protein
Added May 27, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms
Hypoxia-inducible factor augments experimental colitis through an MIF-dependent inflammatory signaling cascade.
Shah YM, Ito S, Morimura K, Chen C, Yim SH, Haase VH, Gonzalez FJ
(2008) Gastroenterology 134: 2036-48, 2048.e1-3
MeSH Terms: Animals, Aryl Hydrocarbon Receptor Nuclear Translocator, Basic Helix-Loop-Helix Transcription Factors, Colitis, Colon, Dextran Sulfate, Disease Models, Animal, Enzyme Inhibitors, Gene Expression Regulation, Hypoxia-Inducible Factor 1, alpha Subunit, Inflammation Mediators, Integrases, Intestinal Mucosa, Intramolecular Oxidoreductases, Isoxazoles, Macrophage Migration-Inhibitory Factors, Mice, Mice, Transgenic, Recombination, Genetic, Signal Transduction, Time Factors, Von Hippel-Lindau Tumor Suppressor Protein
Added August 19, 2013
0 Communities
1 Members
0 Resources
22 MeSH Terms
Hypoxia-inducible factor-1 inhibition in combination with temozolomide treatment exhibits robust antitumor efficacy in vivo.
Li L, Lin X, Shoemaker AR, Albert DH, Fesik SW, Shen Y
(2006) Clin Cancer Res 12: 4747-54
MeSH Terms: Administration, Oral, Angiogenesis Inhibitors, Animals, Antineoplastic Agents, Aryl Hydrocarbon Receptor Nuclear Translocator, Caspases, Cell Death, Cell Line, Tumor, Cell Proliferation, Dacarbazine, Disease Models, Animal, Dose-Response Relationship, Drug, Glucose, Humans, Hypoxia, Indazoles, Mice, Mice, SCID, Phenylurea Compounds, Structure-Activity Relationship, Temozolomide, Transplantation, Heterologous, Xenograft Model Antitumor Assays
Added March 5, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms
Hypoxia-inducible factors in the kidney.
Haase VH
(2006) Am J Physiol Renal Physiol 291: F271-81
MeSH Terms: Animals, Apoptosis, Aryl Hydrocarbon Receptor Nuclear Translocator, Basic Helix-Loop-Helix Transcription Factors, Disease Models, Animal, Erythropoiesis, Gene Expression Regulation, Gene Expression Regulation, Developmental, Gene Expression Regulation, Neoplastic, Humans, Hypoxia, Hypoxia-Inducible Factor 1, alpha Subunit, Kidney, Kidney Neoplasms, Mice, Signal Transduction
Added August 19, 2013
0 Communities
1 Members
0 Resources
16 MeSH Terms
Renal cyst development in mice with conditional inactivation of the von Hippel-Lindau tumor suppressor.
Rankin EB, Tomaszewski JE, Haase VH
(2006) Cancer Res 66: 2576-83
MeSH Terms: Animals, Aryl Hydrocarbon Receptor Nuclear Translocator, Gene Silencing, Hypoxia-Inducible Factor 1, alpha Subunit, Kidney Diseases, Cystic, Kidney Tubules, Proximal, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Transgenic, Mutation, Nephrons, Phosphoenolpyruvate Carboxylase, Promoter Regions, Genetic, Rats, Recombinases, Von Hippel-Lindau Tumor Suppressor Protein, von Hippel-Lindau Disease
Added September 9, 2013
0 Communities
1 Members
1 Resources
18 MeSH Terms
VHL: oxygen sensing and vasculogenesis.
Rathmell WK, Simon MC
(2005) J Thromb Haemost 3: 2627-32
MeSH Terms: Aryl Hydrocarbon Receptor Nuclear Translocator, Blood Vessels, Hematopoiesis, Humans, Hypoxia, Hypoxia-Inducible Factor 1, alpha Subunit, Oxygen, von Hippel-Lindau Disease
Added October 17, 2015
0 Communities
1 Members
0 Resources
8 MeSH Terms
Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice.
Rankin EB, Higgins DF, Walisser JA, Johnson RS, Bradfield CA, Haase VH
(2005) Mol Cell Biol 25: 3163-72
MeSH Terms: Animals, Aryl Hydrocarbon Receptor Nuclear Translocator, DNA-Binding Proteins, Erythropoietin, Gene Deletion, Gene Expression, Gene Silencing, Genes, Tumor Suppressor, Hemangioma, Cavernous, Hepatocytes, Hypoxia-Inducible Factor 1, alpha Subunit, Liver, Liver Neoplasms, Mice, Mice, Knockout, Phosphotransferases (Alcohol Group Acceptor), Polycythemia, Receptors, Aryl Hydrocarbon, Transcription Factors, Tumor Suppressor Proteins, Ubiquitin-Protein Ligases, Vascular Endothelial Growth Factor A, Von Hippel-Lindau Tumor Suppressor Protein, von Hippel-Lindau Disease
Added August 19, 2013
0 Communities
1 Members
0 Resources
24 MeSH Terms