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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 16

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Regulated in Development and DNA Damage Response 1 Deficiency Impairs Autophagy and Mitochondrial Biogenesis in Articular Cartilage and Increases the Severity of Experimental Osteoarthritis.
Alvarez-Garcia O, Matsuzaki T, Olmer M, Plate L, Kelly JW, Lotz MK
(2017) Arthritis Rheumatol 69: 1418-1428
MeSH Terms: AMP-Activated Protein Kinases, Animals, Apoptosis, Arthritis, Experimental, Autophagy, Autophagy-Related Protein 5, Cartilage, Articular, Chondrocytes, DNA-Binding Proteins, Disease Models, Animal, High Mobility Group Proteins, Humans, Immunohistochemistry, Menisci, Tibial, Mice, Mice, Knockout, Microtubule-Associated Proteins, Mitochondria, Organelle Biogenesis, Osteoarthritis, Knee, Oxidative Stress, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Synovial Membrane, Transcription Factors
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Transglutaminase factor XIII promotes arthritis through mechanisms linked to inflammation and bone erosion.
Raghu H, Cruz C, Rewerts CL, Frederick MD, Thornton S, Mullins ES, Schoenecker JG, Degen JL, Flick MJ
(2015) Blood 125: 427-37
MeSH Terms: Animals, Arthritis, Experimental, Blotting, Western, Bone Diseases, Cell Differentiation, Cells, Cultured, Collagen, Factor XIII, Female, Inflammation, Male, Mice, Mice, Inbred DBA, Mice, Knockout, Osteoclasts, RANK Ligand, RNA, Messenger, Real-Time Polymerase Chain Reaction, Reverse Transcriptase Polymerase Chain Reaction
Added February 22, 2016
0 Communities
1 Members
0 Resources
19 MeSH Terms
Reduced T cell-dependent humoral immune response in microsomal prostaglandin E synthase-1 null mice is mediated by nonhematopoietic cells.
Kojima F, Frolov A, Matnani R, Woodward JG, Crofford LJ
(2013) J Immunol 191: 4979-88
MeSH Terms: Animals, Arthritis, Experimental, Bone Marrow Transplantation, Cells, Cultured, Collagen, Female, Immunity, Humoral, Immunoglobulin G, Immunoglobulin M, Interferon-gamma, Interleukin-17, Interleukin-2, Interleukin-4, Intramolecular Oxidoreductases, Male, Mice, Mice, Inbred DBA, Mice, Knockout, Prostaglandin-E Synthases, T-Lymphocytes
Added January 21, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
Anti-inflammatory properties of prostaglandin E2: deletion of microsomal prostaglandin E synthase-1 exacerbates non-immune inflammatory arthritis in mice.
Frolov A, Yang L, Dong H, Hammock BD, Crofford LJ
(2013) Prostaglandins Leukot Essent Fatty Acids 89: 351-8
MeSH Terms: Animals, Arthritis, Experimental, Autoantibodies, Chromatography, Liquid, Collagen Type II, Dinoprostone, Female, Gene Deletion, Inflammation, Intramolecular Oxidoreductases, Joints, Lipid Metabolism, Macrophages, Male, Mice, Neutrophil Infiltration, Neutrophils, Prostaglandin-E Synthases, Severity of Illness Index, Tandem Mass Spectrometry
Added January 21, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
Inflammasome-independent role of apoptosis-associated speck-like protein containing a CARD (ASC) in T cell priming is critical for collagen-induced arthritis.
Ippagunta SK, Brand DD, Luo J, Boyd KL, Calabrese C, Stienstra R, Van de Veerdonk FL, Netea MG, Joosten LA, Lamkanfi M, Kanneganti TD
(2010) J Biol Chem 285: 12454-62
MeSH Terms: Animals, Apoptosis Regulatory Proteins, Arthritis, Experimental, Autoantibodies, CARD Signaling Adaptor Proteins, Carrier Proteins, Caspase 1, Collagen, Cytoskeletal Proteins, Dendritic Cells, Humans, Lymphocyte Activation, Mice, Mice, Inbred C57BL, Mice, Knockout, NLR Family, Pyrin Domain-Containing 3 Protein, T-Lymphocytes
Added March 20, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Defective generation of a humoral immune response is associated with a reduced incidence and severity of collagen-induced arthritis in microsomal prostaglandin E synthase-1 null mice.
Kojima F, Kapoor M, Yang L, Fleishaker EL, Ward MR, Monrad SU, Kottangada PC, Pace CQ, Clark JA, Woodward JG, Crofford LJ
(2008) J Immunol 180: 8361-8
MeSH Terms: Animals, Arthritis, Experimental, Cattle, Collagen Type II, Cyclooxygenase 1, Cyclooxygenase 2, Female, Gene Deletion, Genetic Carrier Screening, Immunoglobulin G, Immunoglobulin M, Incidence, Male, Membrane Proteins, Mice, Mice, Inbred DBA, Mice, Knockout, Microsomes, RNA, Messenger, Severity of Illness Index
Added September 18, 2013
0 Communities
1 Members
0 Resources
20 MeSH Terms
Natural killer T cells ameliorate antibody-induced arthritis in macrophage migration inhibitory factor transgenic mice.
Takagi D, Iwabuchi K, Maeda M, Nakamaru Y, Furuta Y, Fukuda S, Van Kaer L, Nishihira J, OnoƩ K
(2006) Int J Mol Med 18: 829-36
MeSH Terms: Animals, Antibodies, Monoclonal, Antigens, CD, Antigens, Differentiation, T-Lymphocyte, Arthritis, Experimental, Collagen Type II, Galactosylceramides, Interleukin-4, Interleukin-6, Killer Cells, Natural, Lectins, C-Type, Lipopolysaccharides, Macrophage Migration-Inhibitory Factors, Mice, Mice, Inbred C57BL, Mice, Transgenic, T-Lymphocytes
Added December 10, 2013
0 Communities
1 Members
0 Resources
17 MeSH Terms
Tie2 receptor tyrosine kinase, a major mediator of tumor necrosis factor alpha-induced angiogenesis in rheumatoid arthritis.
DeBusk LM, Chen Y, Nishishita T, Chen J, Thomas JW, Lin PC
(2003) Arthritis Rheum 48: 2461-71
MeSH Terms: Angiogenesis Inducing Agents, Angiopoietin-1, Animals, Arthritis, Experimental, Arthritis, Rheumatoid, Endothelium, Humans, Membrane Glycoproteins, Mice, Mice, Inbred DBA, NF-kappa B, Neovascularization, Pathologic, Receptor Protein-Tyrosine Kinases, Receptor, TIE-2, Signal Transduction, Synovial Membrane, Tumor Necrosis Factor-alpha
Added November 6, 2013
2 Communities
1 Members
0 Resources
17 MeSH Terms
Synaptic plasticity in the amygdala in a model of arthritic pain: differential roles of metabotropic glutamate receptors 1 and 5.
Neugebauer V, Li W, Bird GC, Bhave G, Gereau RW
(2003) J Neurosci 23: 52-63
MeSH Terms: Amygdala, Animals, Arthritis, Experimental, Behavior, Animal, Cell Membrane, Cells, Cultured, Electric Stimulation, Excitatory Postsynaptic Potentials, Male, Neuronal Plasticity, Neurons, Pain, Patch-Clamp Techniques, Rats, Rats, Sprague-Dawley, Receptor, Metabotropic Glutamate 5, Receptors, Metabotropic Glutamate, Synaptic Transmission, Up-Regulation
Added March 24, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms
Constitutive expression of BCL-X(L) in the T lineage attenuates collagen-induced arthritis in Bcl-X(L) transgenic mice.
Chen Y, Rosloniec E, Price J, Boothby M, Chen J
(2002) Arthritis Rheum 46: 514-21
MeSH Terms: Animals, Apoptosis, Arthritis, Experimental, Cell Cycle, Cell Lineage, Gene Expression, Interferon-gamma, Lymphoid Tissue, Mice, Mice, Inbred DBA, Mice, Transgenic, Proto-Oncogene Proteins c-bcl-2, T-Lymphocytes, Transgenes, bcl-X Protein
Added December 10, 2013
1 Communities
2 Members
0 Resources
15 MeSH Terms