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Central EP3 (E Prostanoid 3) Receptors Mediate Salt-Sensitive Hypertension and Immune Activation.
Xiao L, Itani HA, do Carmo LS, Carver LS, Breyer RM, Harrison DG
(2019) Hypertension 74: 1507-1515
MeSH Terms: Adaptive Immunity, Analysis of Variance, Animals, Biomarkers, Biopsy, Needle, Brain, Dinoprostone, Disease Models, Animal, Female, Flow Cytometry, Hypertension, Immunohistochemistry, Male, Mice, Mice, Inbred C57BL, NG-Nitroarginine Methyl Ester, Random Allocation, Real-Time Polymerase Chain Reaction, Receptors, Prostaglandin E, EP3 Subtype, Sodium, Dietary
Added December 3, 2019
1 Communities
0 Members
0 Resources
20 MeSH Terms
Dietary Arginine Regulates Severity of Experimental Colitis and Affects the Colonic Microbiome.
Singh K, Gobert AP, Coburn LA, Barry DP, Allaman M, Asim M, Luis PB, Schneider C, Milne GL, Boone HH, Shilts MH, Washington MK, Das SR, Piazuelo MB, Wilson KT
(2019) Front Cell Infect Microbiol 9: 66
MeSH Terms: Animals, Arginine, Citrobacter rodentium, Colitis, Colon, Dextran Sulfate, Diet, Disease Models, Animal, Enterobacteriaceae Infections, Gastrointestinal Microbiome, Histocytochemistry, Mice, Inbred C57BL, Treatment Outcome
Added April 12, 2019
0 Communities
2 Members
0 Resources
13 MeSH Terms
Methylglyoxal-derived posttranslational arginine modifications are abundant histone marks.
Galligan JJ, Wepy JA, Streeter MD, Kingsley PJ, Mitchener MM, Wauchope OR, Beavers WN, Rose KL, Wang T, Spiegel DA, Marnett LJ
(2018) Proc Natl Acad Sci U S A 115: 9228-9233
MeSH Terms: Arginine, HEK293 Cells, Histones, Humans, Lactoylglutathione Lyase, Protein Processing, Post-Translational, Pyruvaldehyde, Transcription, Genetic
Added April 12, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Acute Nitric Oxide Synthase Inhibition Accelerates Transendothelial Insulin Efflux In Vivo.
Williams IM, McClatchey PM, Bracy DP, Valenzuela FA, Wasserman DH
(2018) Diabetes 67: 1962-1975
MeSH Terms: Animals, Biological Transport, Blood Pressure, Blotting, Western, Glucose, Insulin, Male, Mice, Inbred C57BL, NG-Nitroarginine Methyl Ester, Nitric Oxide, Nitric Oxide Synthase, Transendothelial and Transepithelial Migration
Added March 26, 2019
1 Communities
1 Members
0 Resources
MeSH Terms
Structural basis of ligand binding modes at the neuropeptide Y Y receptor.
Yang Z, Han S, Keller M, Kaiser A, Bender BJ, Bosse M, Burkert K, Kögler LM, Wifling D, Bernhardt G, Plank N, Littmann T, Schmidt P, Yi C, Li B, Ye S, Zhang R, Xu B, Larhammar D, Stevens RC, Huster D, Meiler J, Zhao Q, Beck-Sickinger AG, Buschauer A, Wu B
(2018) Nature 556: 520-524
MeSH Terms: Arginine, Binding Sites, Crystallography, X-Ray, Dihydropyridines, Diphenylacetic Acids, Humans, Inositol Phosphates, Ligands, Molecular Docking Simulation, Mutant Proteins, Mutation, Neuropeptide Y, Nuclear Magnetic Resonance, Biomolecular, Phenylurea Compounds, Protein Binding, Receptors, Neuropeptide Y, Structure-Activity Relationship, Substrate Specificity
Added March 21, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Assessing glycation-mediated changes in human cortical bone with Raman spectroscopy.
Unal M, Uppuganti S, Leverant CJ, Creecy A, Granke M, Voziyan P, Nyman JS
(2018) J Biophotonics 11: e201700352
MeSH Terms: Amides, Arginine, Cortical Bone, Female, Glycation End Products, Advanced, Glycosylation, Humans, Kinetics, Lysine, Male, Middle Aged, Spectrum Analysis, Raman
Added March 27, 2018
1 Communities
1 Members
0 Resources
12 MeSH Terms
Low bone toughness in the TallyHO model of juvenile type 2 diabetes does not worsen with age.
Creecy A, Uppuganti S, Unal M, Clay Bunn R, Voziyan P, Nyman JS
(2018) Bone 110: 204-214
MeSH Terms: Aging, Animals, Arginine, Bone Density, Chromatography, High Pressure Liquid, Diabetes Mellitus, Type 2, Femur, Fractures, Bone, Lysine, Male, Mice, Spectrum Analysis, Raman, X-Ray Microtomography
Added February 19, 2018
1 Communities
1 Members
0 Resources
13 MeSH Terms
Desmopressin acetate nasal spray for adults with nocturia.
Cohn JA, Kowalik CG, Reynolds WS, Kaufman MR, Milam DF, Dmochowski RR, Wein AJ
(2017) Expert Rev Clin Pharmacol 10: 1281-1293
MeSH Terms: Adult, Aged, Antidiuretic Agents, Deamino Arginine Vasopressin, Humans, Hyponatremia, Incidence, Middle Aged, Nasal Sprays, Nocturia, Off-Label Use
Added September 16, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Quantitative Analysis and Discovery of Lysine and Arginine Modifications.
Galligan JJ, Kingsley PJ, Wauchope OR, Mitchener MM, Camarillo JM, Wepy JA, Harris PS, Fritz KS, Marnett LJ
(2017) Anal Chem 89: 1299-1306
MeSH Terms: Arginine, Chromatography, High Pressure Liquid, HEK293 Cells, Histones, Humans, Hydrolysis, Jumonji Domain-Containing Histone Demethylases, Lysine, Peptides, Protein Processing, Post-Translational, Recombinant Proteins, Tandem Mass Spectrometry
Added April 22, 2018
0 Communities
2 Members
0 Resources
12 MeSH Terms
A Deep Hydrophobic Binding Cavity is the Main Interaction for Different Y R Antagonists.
Burkert K, Zellmann T, Meier R, Kaiser A, Stichel J, Meiler J, Mittapalli GK, Roberts E, Beck-Sickinger AG
(2017) ChemMedChem 12: 75-85
MeSH Terms: Animals, Arginine, Benzazepines, Binding Sites, COS Cells, Cells, Cultured, Chlorocebus aethiops, Dose-Response Relationship, Drug, HEK293 Cells, Humans, Hydrophobic and Hydrophilic Interactions, Molecular Docking Simulation, Molecular Structure, Receptors, Neuropeptide Y, Structure-Activity Relationship
Added April 8, 2017
1 Communities
1 Members
0 Resources
15 MeSH Terms