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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 10

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Replication bypass of the trans-4-Hydroxynonenal-derived (6S,8R,11S)-1,N(2)-deoxyguanosine DNA adduct by the sulfolobus solfataricus DNA polymerase IV.
Banerjee S, Christov PP, Kozekova A, Rizzo CJ, Egli M, Stone MP
(2012) Chem Res Toxicol 25: 422-35
MeSH Terms: Aldehydes, Archaeal Proteins, DNA Adducts, DNA Polymerase beta, DNA Replication, Deoxyguanosine, Sulfolobus solfataricus
Added March 7, 2014
0 Communities
3 Members
0 Resources
7 MeSH Terms
Effect of N2-guanyl modifications on early steps in catalysis of polymerization by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W.
Zhang H, Guengerich FP
(2010) J Mol Biol 395: 1007-18
MeSH Terms: Amino Acid Substitution, Archaeal Proteins, Base Sequence, Catalytic Domain, DNA Adducts, DNA Polymerase beta, DNA Replication, DNA, Archaeal, Deoxycytosine Nucleotides, Kinetics, Molecular Structure, Mutagenesis, Site-Directed, Nucleic Acid Conformation, Protein Conformation, Recombinant Proteins, Spectrometry, Fluorescence, Sulfolobus solfataricus
Added March 7, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Frameshift deletion by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W is selective for purines and involves normal conformational change followed by slow phosphodiester bond formation.
Zhang H, Beckman JW, Guengerich FP
(2009) J Biol Chem 284: 35144-53
MeSH Terms: Archaeal Proteins, DNA Polymerase beta, DNA, Archaeal, Frameshift Mutation, Humans, Hydrogen Bonding, Molecular Structure, Nucleic Acid Conformation, Purines, Sulfolobus solfataricus
Added March 26, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Structure-function relationships in miscoding by Sulfolobus solfataricus DNA polymerase Dpo4: guanine N2,N2-dimethyl substitution produces inactive and miscoding polymerase complexes.
Zhang H, Eoff RL, Kozekov ID, Rizzo CJ, Egli M, Guengerich FP
(2009) J Biol Chem 284: 17687-99
MeSH Terms: Archaeal Proteins, Binding Sites, Catalysis, Crystallography, X-Ray, DNA Adducts, DNA-Directed DNA Polymerase, Guanine, Hydrogen Bonding, Kinetics, Nucleic Acid Conformation, Protein Binding, Protein Conformation, Structure-Activity Relationship, Substrate Specificity, Sulfolobus solfataricus
Added March 26, 2014
0 Communities
3 Members
0 Resources
15 MeSH Terms
Structural and functional analysis of Sulfolobus solfataricus Y-family DNA polymerase Dpo4-catalyzed bypass of the malondialdehyde-deoxyguanosine adduct.
Eoff RL, Stafford JB, Szekely J, Rizzo CJ, Egli M, Guengerich FP, Marnett LJ
(2009) Biochemistry 48: 7079-88
MeSH Terms: Animals, Archaeal Proteins, Base Sequence, Catalytic Domain, Crystallography, X-Ray, DNA, DNA Adducts, DNA Replication, DNA-Directed DNA Polymerase, Deoxyguanosine, Macromolecular Substances, Malondialdehyde, Models, Molecular, Molecular Sequence Data, Molecular Structure, Nucleic Acid Conformation, Protein Conformation, Sulfolobus solfataricus
Added March 26, 2014
0 Communities
4 Members
0 Resources
18 MeSH Terms
Versatility of Y-family Sulfolobus solfataricus DNA polymerase Dpo4 in translesion synthesis past bulky N2-alkylguanine adducts.
Zhang H, Eoff RL, Kozekov ID, Rizzo CJ, Egli M, Guengerich FP
(2009) J Biol Chem 284: 3563-76
MeSH Terms: Archaeal Proteins, DNA Adducts, DNA Polymerase beta, DNA Replication, DNA, Archaeal, Deoxycytosine Nucleotides, Kinetics, Protein Conformation, Sulfolobus solfataricus
Added March 7, 2014
0 Communities
3 Members
0 Resources
9 MeSH Terms
Insertion of dNTPs opposite the 1,N2-propanodeoxyguanosine adduct by Sulfolobus solfataricus P2 DNA polymerase IV.
Wang Y, Musser SK, Saleh S, Marnett LJ, Egli M, Stone MP
(2008) Biochemistry 47: 7322-34
MeSH Terms: Animals, Archaeal Proteins, DNA, DNA Polymerase beta, Deoxyguanosine, Dideoxynucleotides, Humans, Malondialdehyde, Oligodeoxyribonucleotides, Rodentia, Substrate Specificity, Sulfolobus solfataricus
Added March 5, 2014
0 Communities
3 Members
0 Resources
12 MeSH Terms
Hydrogen bonding of 7,8-dihydro-8-oxodeoxyguanosine with a charged residue in the little finger domain determines miscoding events in Sulfolobus solfataricus DNA polymerase Dpo4.
Eoff RL, Irimia A, Angel KC, Egli M, Guengerich FP
(2007) J Biol Chem 282: 19831-43
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Amino Acid Substitution, Archaeal Proteins, Crystallography, X-Ray, DNA Polymerase beta, DNA, Archaeal, Deoxyguanosine, Hydrogen Bonding, Mutation, Missense, Protein Structure, Tertiary, Sulfolobus solfataricus
Added March 5, 2014
0 Communities
2 Members
0 Resources
11 MeSH Terms
Molecular basis of selectivity of nucleoside triphosphate incorporation opposite O6-benzylguanine by sulfolobus solfataricus DNA polymerase Dpo4: steady-state and pre-steady-state kinetics and x-ray crystallography of correct and incorrect pairing.
Eoff RL, Angel KC, Egli M, Guengerich FP
(2007) J Biol Chem 282: 13573-84
MeSH Terms: Archaeal Proteins, Base Pair Mismatch, Base Pairing, Crystallography, X-Ray, DNA Polymerase beta, DNA Replication, DNA, Archaeal, DNA-Directed DNA Polymerase, Deoxyribonucleotides, Guanine, HIV Reverse Transcriptase, Humans, Kinetics, Mass Spectrometry, Sulfolobus solfataricus
Added March 5, 2014
0 Communities
2 Members
0 Resources
15 MeSH Terms
Phylogenetic profiles for the prediction of protein-protein interactions: how to select reference organisms?
Sun J, Li Y, Zhao Z
(2007) Biochem Biophys Res Commun 353: 985-91
MeSH Terms: Algorithms, Animals, Archaeal Proteins, Bacterial Proteins, Computational Biology, Databases, Genetic, Eukaryotic Cells, Genome, Humans, Phylogeny, Protein Binding, Protein Interaction Mapping, Reproducibility of Results
Added March 5, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms