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Results: 1 to 10 of 15

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Structural Biology of the HEAT-Like Repeat Family of DNA Glycosylases.
Shi R, Shen XX, Rokas A, Eichman BF
(2018) Bioessays 40: e1800133
MeSH Terms: Archaea, Bacteria, Crystallography, X-Ray, DNA, DNA Damage, DNA Glycosylases, DNA Repair, Eukaryota, Protein Conformation
Added August 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Antibacterial gene transfer across the tree of life.
Metcalf JA, Funkhouser-Jones LJ, Brileya K, Reysenbach AL, Bordenstein SR
(2014) Elife 3:
MeSH Terms: Amino Acid Sequence, Anti-Bacterial Agents, Archaea, Bacteria, Coculture Techniques, Escherichia coli, Gene Transfer, Horizontal, Genes, Bacterial, Microbial Viability, Models, Molecular, Molecular Sequence Data, Muramidase, Phylogeny, RNA, Ribosomal
Added October 8, 2015
0 Communities
1 Members
0 Resources
14 MeSH Terms
Differential furanose selection in the active sites of archaeal DNA polymerases probed by fixed-conformation nucleotide analogues.
Ketkar A, Zafar MK, Banerjee S, Marquez VE, Egli M, Eoff RL
(2012) Biochemistry 51: 9234-44
MeSH Terms: Carbohydrate Conformation, Catalytic Domain, Crystallography, X-Ray, DNA, Archaeal, DNA-Directed DNA Polymerase, Deoxyadenine Nucleotides, Deoxyribonucleotides, Nucleic Acid Conformation, Substrate Specificity, Sulfolobus solfataricus
Added May 27, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Translesion synthesis across 1,N6-(2-hydroxy-3-hydroxymethylpropan-1,3-diyl)-2'-deoxyadenosine (1,N6-γ-HMHP-dA) adducts by human and archebacterial DNA polymerases.
Kotapati S, Maddukuri L, Wickramaratne S, Seneviratne U, Goggin M, Pence MG, Villalta P, Guengerich FP, Marnett L, Tretyakova N
(2012) J Biol Chem 287: 38800-11
MeSH Terms: Archaea, Base Sequence, DNA Adducts, DNA Damage, DNA Repair, DNA Replication, DNA-Directed DNA Polymerase, Deoxyadenosines, Gene Deletion, Humans, Kinetics, Mass Spectrometry, Models, Chemical, Molecular Sequence Data, Oligonucleotides, Recombinant Proteins, Sequence Analysis, DNA, Spectrometry, Mass, Electrospray Ionization, Tandem Mass Spectrometry
Added March 26, 2014
0 Communities
2 Members
0 Resources
19 MeSH Terms
Replication bypass of the trans-4-Hydroxynonenal-derived (6S,8R,11S)-1,N(2)-deoxyguanosine DNA adduct by the sulfolobus solfataricus DNA polymerase IV.
Banerjee S, Christov PP, Kozekova A, Rizzo CJ, Egli M, Stone MP
(2012) Chem Res Toxicol 25: 422-35
MeSH Terms: Aldehydes, Archaeal Proteins, DNA Adducts, DNA Polymerase beta, DNA Replication, Deoxyguanosine, Sulfolobus solfataricus
Added March 7, 2014
0 Communities
3 Members
0 Resources
7 MeSH Terms
Effect of N2-guanyl modifications on early steps in catalysis of polymerization by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W.
Zhang H, Guengerich FP
(2010) J Mol Biol 395: 1007-18
MeSH Terms: Amino Acid Substitution, Archaeal Proteins, Base Sequence, Catalytic Domain, DNA Adducts, DNA Polymerase beta, DNA Replication, DNA, Archaeal, Deoxycytosine Nucleotides, Kinetics, Molecular Structure, Mutagenesis, Site-Directed, Nucleic Acid Conformation, Protein Conformation, Recombinant Proteins, Spectrometry, Fluorescence, Sulfolobus solfataricus
Added March 7, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Frameshift deletion by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W is selective for purines and involves normal conformational change followed by slow phosphodiester bond formation.
Zhang H, Beckman JW, Guengerich FP
(2009) J Biol Chem 284: 35144-53
MeSH Terms: Archaeal Proteins, DNA Polymerase beta, DNA, Archaeal, Frameshift Mutation, Humans, Hydrogen Bonding, Molecular Structure, Nucleic Acid Conformation, Purines, Sulfolobus solfataricus
Added March 26, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Structure-function relationships in miscoding by Sulfolobus solfataricus DNA polymerase Dpo4: guanine N2,N2-dimethyl substitution produces inactive and miscoding polymerase complexes.
Zhang H, Eoff RL, Kozekov ID, Rizzo CJ, Egli M, Guengerich FP
(2009) J Biol Chem 284: 17687-99
MeSH Terms: Archaeal Proteins, Binding Sites, Catalysis, Crystallography, X-Ray, DNA Adducts, DNA-Directed DNA Polymerase, Guanine, Hydrogen Bonding, Kinetics, Nucleic Acid Conformation, Protein Binding, Protein Conformation, Structure-Activity Relationship, Substrate Specificity, Sulfolobus solfataricus
Added March 26, 2014
0 Communities
3 Members
0 Resources
15 MeSH Terms
Structural and functional analysis of Sulfolobus solfataricus Y-family DNA polymerase Dpo4-catalyzed bypass of the malondialdehyde-deoxyguanosine adduct.
Eoff RL, Stafford JB, Szekely J, Rizzo CJ, Egli M, Guengerich FP, Marnett LJ
(2009) Biochemistry 48: 7079-88
MeSH Terms: Animals, Archaeal Proteins, Base Sequence, Catalytic Domain, Crystallography, X-Ray, DNA, DNA Adducts, DNA Replication, DNA-Directed DNA Polymerase, Deoxyguanosine, Macromolecular Substances, Malondialdehyde, Models, Molecular, Molecular Sequence Data, Molecular Structure, Nucleic Acid Conformation, Protein Conformation, Sulfolobus solfataricus
Added March 26, 2014
0 Communities
4 Members
0 Resources
18 MeSH Terms
Versatility of Y-family Sulfolobus solfataricus DNA polymerase Dpo4 in translesion synthesis past bulky N2-alkylguanine adducts.
Zhang H, Eoff RL, Kozekov ID, Rizzo CJ, Egli M, Guengerich FP
(2009) J Biol Chem 284: 3563-76
MeSH Terms: Archaeal Proteins, DNA Adducts, DNA Polymerase beta, DNA Replication, DNA, Archaeal, Deoxycytosine Nucleotides, Kinetics, Protein Conformation, Sulfolobus solfataricus
Added March 7, 2014
0 Communities
3 Members
0 Resources
9 MeSH Terms