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Endocannabinoid Signaling Collapse Mediates Stress-Induced Amygdalo-Cortical Strengthening.
Marcus DJ, Bedse G, Gaulden AD, Ryan JD, Kondev V, Winters ND, Rosas-Vidal LE, Altemus M, Mackie K, Lee FS, Delpire E, Patel S
(2020) Neuron 105: 1062-1076.e6
MeSH Terms: Animals, Anxiety, Arachidonic Acids, Basolateral Nuclear Complex, Endocannabinoids, Glutamic Acid, Glycerides, Male, Mice, Neural Pathways, Prefrontal Cortex, Restraint, Physical, Stress, Psychological, Synaptic Transmission
Added March 3, 2020
0 Communities
2 Members
0 Resources
14 MeSH Terms
Arachidonic Acid Kills Staphylococcus aureus through a Lipid Peroxidation Mechanism.
Beavers WN, Monteith AJ, Amarnath V, Mernaugh RL, Roberts LJ, Chazin WJ, Davies SS, Skaar EP
(2019) mBio 10:
MeSH Terms: Animals, Anti-Bacterial Agents, Arachidonic Acid, Brain, Dose-Response Relationship, Drug, Drug Resistance, Bacterial, Female, Kidney, Lipid Peroxidation, Lipids, Mice, Mice, Inbred BALB C, Microbial Sensitivity Tests, Mutation, Neutrophils, Oxidative Stress, Reactive Oxygen Species, Spleen, Staphylococcal Infections, Staphylococcus aureus, Teichoic Acids
Added March 11, 2020
0 Communities
1 Members
0 Resources
21 MeSH Terms
Aspects of Prostaglandin Glycerol Ester Biology.
Kingsley PJ, Rouzer CA, Morgan AJ, Patel S, Marnett LJ
(2019) Adv Exp Med Biol 1161: 77-88
MeSH Terms: Animals, Arachidonic Acids, Cyclooxygenase 2, Endocannabinoids, Glycerides, Glyceryl Ethers, Prostaglandins
Added March 12, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Isolevuglandins and cardiovascular disease.
Davies SS, May-Zhang LS
(2018) Prostaglandins Other Lipid Mediat 139: 29-35
MeSH Terms: Arachidonic Acid, Atherosclerosis, Cardiovascular Diseases, Humans, Lipid Peroxidation, Lipids
Added October 26, 2018
1 Communities
2 Members
0 Resources
6 MeSH Terms
The Cytochrome P450 Slow Metabolizers CYP2C9*2 and CYP2C9*3 Directly Regulate Tumorigenesis via Reduced Epoxyeicosatrienoic Acid Production.
Sausville LN, Gangadhariah MH, Chiusa M, Mei S, Wei S, Zent R, Luther JM, Shuey MM, Capdevila JH, Falck JR, Guengerich FP, Williams SM, Pozzi A
(2018) Cancer Res 78: 4865-4877
MeSH Terms: Animals, Arachidonic Acid, Arachidonic Acids, Carcinogenesis, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Cytochrome P-450 CYP2C9, Cytochrome P-450 Enzyme System, Eicosanoids, Endothelial Cells, Humans, Mice, Polymorphism, Single Nucleotide, Xenograft Model Antitumor Assays
Added October 25, 2018
0 Communities
2 Members
0 Resources
14 MeSH Terms
Detection of Cyclooxygenase-2-Derived Oxygenation Products of the Endogenous Cannabinoid 2-Arachidonoylglycerol in Mouse Brain.
Morgan AJ, Kingsley PJ, Mitchener MM, Altemus M, Patrick TA, Gaulden AD, Marnett LJ, Patel S
(2018) ACS Chem Neurosci 9: 1552-1559
MeSH Terms: Animals, Arachidonic Acids, Brain, Cyclooxygenase 2, Cyclooxygenase 2 Inhibitors, Endocannabinoids, Esters, Female, Glycerides, Inflammation, Lipopolysaccharides, Male, Mice, Inbred C57BL, Mice, Transgenic, Monoacylglycerol Lipases, Neurons, Oxidation-Reduction, Prostaglandins
Added October 8, 2018
0 Communities
2 Members
0 Resources
18 MeSH Terms
Role of Striatal Direct Pathway 2-Arachidonoylglycerol Signaling in Sociability and Repetitive Behavior.
Shonesy BC, Parrish WP, Haddad HK, Stephenson JR, Báldi R, Bluett RJ, Marks CR, Centanni SW, Folkes OM, Spiess K, Augustin SM, Mackie K, Lovinger DM, Winder DG, Patel S, Colbran RJ
(2018) Biol Psychiatry 84: 304-315
MeSH Terms: Animals, Arachidonic Acids, Autism Spectrum Disorder, Corpus Striatum, Endocannabinoids, Glycerides, Mice, Mice, Knockout, Receptor, Adenosine A2A, Receptors, Dopamine D1, Signal Transduction, Social Behavior, Synaptic Transmission
Added March 21, 2018
0 Communities
2 Members
0 Resources
13 MeSH Terms
PUFA levels in erythrocyte membrane phospholipids are differentially associated with colorectal adenoma risk.
Rifkin SB, Shrubsole MJ, Cai Q, Smalley WE, Ness RM, Swift LL, Zheng W, Murff HJ
(2017) Br J Nutr 117: 1615-1622
MeSH Terms: Adenoma, Arachidonic Acid, Biomarkers, Case-Control Studies, Colorectal Neoplasms, Diet, Eicosapentaenoic Acid, Erythrocyte Membrane, Female, Humans, Logistic Models, Male, Middle Aged, Odds Ratio, Phospholipids, Risk Factors, Tennessee
Added April 3, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Functional Redundancy Between Canonical Endocannabinoid Signaling Systems in the Modulation of Anxiety.
Bedse G, Hartley ND, Neale E, Gaulden AD, Patrick TA, Kingsley PJ, Uddin MJ, Plath N, Marnett LJ, Patel S
(2017) Biol Psychiatry 82: 488-499
MeSH Terms: Adaptation, Ocular, Animals, Anti-Anxiety Agents, Anxiety, Arachidonic Acids, Benzodioxoles, Brain, Cannabinoid Receptor Agonists, Cyclohexanols, Disease Models, Animal, Dronabinol, Endocannabinoids, Excitatory Postsynaptic Potentials, Glycerides, Heterocyclic Compounds, 1-Ring, Locomotion, Male, Mice, Mice, Inbred ICR, Piperidines, Polyunsaturated Alkamides, Pyridines, Signal Transduction
Added April 26, 2017
0 Communities
3 Members
0 Resources
23 MeSH Terms
Endocannabinoid signalling modulates susceptibility to traumatic stress exposure.
Bluett RJ, Báldi R, Haymer A, Gaulden AD, Hartley ND, Parrish WP, Baechle J, Marcus DJ, Mardam-Bey R, Shonesy BC, Uddin MJ, Marnett LJ, Mackie K, Colbran RJ, Winder DG, Patel S
(2017) Nat Commun 8: 14782
MeSH Terms: Amygdala, Animals, Anxiety, Arachidonic Acids, Behavior, Animal, Benzodioxoles, Disease Susceptibility, Dronabinol, Endocannabinoids, Excitatory Postsynaptic Potentials, Female, Glutamates, Glycerides, Hippocampus, Lipoprotein Lipase, Male, Mice, Inbred ICR, Mice, Knockout, Phenotype, Piperidines, Resilience, Psychological, Signal Transduction, Stress, Psychological, Synapses
Added April 7, 2017
0 Communities
4 Members
0 Resources
24 MeSH Terms