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2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H.
Li F, Sarkhel S, Wilds CJ, Wawrzak Z, Prakash TP, Manoharan M, Egli M
(2006) Biochemistry 45: 4141-52
MeSH Terms: Arabinonucleotides, Nucleic Acid Conformation, Nucleic Acid Heteroduplexes, Ribonuclease H
Added March 5, 2014
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4 MeSH Terms
Structural basis of cleavage by RNase H of hybrids of arabinonucleic acids and RNA.
Minasov G, Teplova M, Nielsen P, Wengel J, Egli M
(2000) Biochemistry 39: 3525-32
MeSH Terms: Arabinonucleotides, Crystallization, Crystallography, X-Ray, DNA, Hydrolysis, Models, Molecular, Nucleic Acid Conformation, Nucleic Acid Heteroduplexes, Oligodeoxyribonucleotides, RNA, Ribonuclease H, Structure-Activity Relationship, Thionucleotides
Added May 27, 2014
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1 Members
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13 MeSH Terms