Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 8 of 8

Publication Record

Connections

The hyperglycemic byproduct methylglyoxal impairs anticoagulant activity through covalent adduction of antithrombin III.
Jacobson R, Mignemi N, Rose K, O'Rear L, Sarilla S, Hamm HE, Barnett JV, Verhamme IM, Schoenecker J
(2014) Thromb Res 134: 1350-7
MeSH Terms: Anticoagulants, Antithrombin III, Blood Coagulation, Dose-Response Relationship, Drug, Heparin, Humans, Hyperglycemia, Protein Binding, Pyruvaldehyde
Added January 20, 2015
0 Communities
4 Members
0 Resources
9 MeSH Terms
Persistent hypocoagulability in patients with septic shock predicts greater hospital mortality: impact of impaired thrombin generation.
Massion PB, Peters P, Ledoux D, Zimermann V, Canivet JL, Massion PP, Damas P, Gothot A
(2012) Intensive Care Med 38: 1326-35
MeSH Terms: Aged, Anticoagulants, Antithrombin III, Blood Coagulation Disorders, Blood Coagulation Factors, Female, Fibrin, Hospital Mortality, Humans, Intensive Care Units, Logistic Models, Longitudinal Studies, Male, Middle Aged, Partial Thromboplastin Time, Prospective Studies, Protein C, Prothrombin Time, Shock, Septic, Thrombin
Added March 10, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Severe factor XI deficiency caused by a Gly555 to Glu mutation (factor XI-Glu555): a cross-reactive material positive variant defective in factor IX activation.
Zivelin A, Ogawa T, Bulvik S, Landau M, Toomey JR, Lane J, Seligsohn U, Gailani D
(2004) J Thromb Haemost 2: 1782-9
MeSH Terms: Antithrombin III, Binding Sites, Factor IX, Factor XI, Factor XI Deficiency, Homozygote, Humans, Kinetics, Models, Molecular, Mutation, Missense, Protein Binding, Static Electricity
Added May 19, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Characterization of a heparin binding site on the heavy chain of factor XI.
Zhao M, Abdel-Razek T, Sun MF, Gailani D
(1998) J Biol Chem 273: 31153-9
MeSH Terms: Alanine, Amino Acids, Diamino, Antithrombin III, Binding Sites, Chromatography, Affinity, Complement C1 Inactivator Proteins, Complement C1 Inhibitor Protein, Enzyme Activation, Factor XI, Factor XIa, Glutamic Acid, Heparin, Mutation, Recombinant Proteins, Sepharose
Added May 19, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Inactivation of thrombin by antithrombin is accompanied by inactivation of regulatory exosite I.
Bock PE, Olson ST, Björk I
(1997) J Biol Chem 272: 19837-45
MeSH Terms: Antithrombin III, Binding Sites, Binding, Competitive, Catalysis, Hirudins, Humans, Kinetics, Macromolecular Substances, Spectrometry, Fluorescence, Thrombin
Added January 20, 2015
0 Communities
1 Members
0 Resources
10 MeSH Terms
Role of the catalytic serine in the interactions of serine proteinases with protein inhibitors of the serpin family. Contribution of a covalent interaction to the binding energy of serpin-proteinase complexes.
Olson ST, Bock PE, Kvassman J, Shore JD, Lawrence DA, Ginsburg D, Björk I
(1995) J Biol Chem 270: 30007-17
MeSH Terms: Animals, Antithrombin III, Binding Sites, Catalysis, Cattle, Humans, Kinetics, Mathematics, Models, Theoretical, Serine, Serine Endopeptidases, Serpins, Trypsin, Trypsin Inhibitors
Added January 20, 2015
0 Communities
1 Members
0 Resources
14 MeSH Terms
Assessment of interference by heparin cofactor II in the DuPont aca antithrombin-III assay.
Hortin GL, Tollefsen DM, Santoro SA
(1988) Am J Clin Pathol 89: 515-7
MeSH Terms: Antithrombin III, Antithrombin III Deficiency, Antithrombins, Cross Reactions, Diagnostic Errors, Glycoproteins, Heparin Cofactor II, Humans, Reagent Kits, Diagnostic
Added March 5, 2014
1 Communities
1 Members
0 Resources
9 MeSH Terms
Quantitative evaluation of solution equilibrium binding interactions by affinity partitioning: application to specific and nonspecific protein-heparin interactions.
Olson ST, Bock PE, Sheffer R
(1991) Arch Biochem Biophys 286: 533-45
MeSH Terms: Antithrombin III, Binding, Competitive, Chromatography, Affinity, Heparin, Kinetics, Mathematics, Models, Theoretical, Protein Binding, Proteins, Solutions, Thrombin
Added January 20, 2015
0 Communities
1 Members
0 Resources
11 MeSH Terms