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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 31

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Genomic Variants of Cytarabine Sensitivity Associated with Treatment-Related Mortality in Pediatric AML: A Report from the Children's Oncology Group.
Phillips CL, Lane A, Gerbing RB, Alonzo TA, Wilkey A, Radloff G, Lange B, Gamazon ER, Dolan ME, Davies SM
(2020) Clin Cancer Res 26: 2891-2897
MeSH Terms: Antimetabolites, Antineoplastic, Biomarkers, Tumor, Child, Cytarabine, Follow-Up Studies, Gene Expression Regulation, Neoplastic, Humans, Leukemia, Myeloid, Acute, Polymorphism, Single Nucleotide, Prognosis, Prospective Studies, Survival Rate
Added March 10, 2020
0 Communities
1 Members
0 Resources
12 MeSH Terms
Temperature-sensitive magnetic drug carriers for concurrent gemcitabine chemohyperthermia.
Kim DH, Guo Y, Zhang Z, Procissi D, Nicolai J, Omary RA, Larson AC
(2014) Adv Healthc Mater 3: 714-24
MeSH Terms: Animals, Antimetabolites, Antineoplastic, Cell Line, Tumor, Cell Survival, Cellulose, Deoxycytidine, Drug Carriers, Hyperthermia, Induced, Magnetite Nanoparticles, Mice, Mice, Inbred BALB C, Mice, Nude, Pancreatic Neoplasms, Tissue Distribution, Xenograft Model Antitumor Assays
Added March 20, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Loss of Smad4 in colorectal cancer induces resistance to 5-fluorouracil through activating Akt pathway.
Zhang B, Zhang B, Chen X, Bae S, Singh K, Washington MK, Datta PK
(2014) Br J Cancer 110: 946-57
MeSH Terms: Animals, Antimetabolites, Antineoplastic, Apoptosis Regulatory Proteins, Cell Cycle Proteins, Cell Line, Tumor, Cell Movement, Cell Proliferation, Cell Survival, Chromones, Colorectal Neoplasms, Drug Resistance, Neoplasm, Enzyme Activation, Enzyme Inhibitors, Fluorouracil, Humans, Inhibitor of Apoptosis Proteins, Mice, Mice, Inbred BALB C, Morpholines, Neoplasm Invasiveness, Neoplasm Metastasis, Neoplasm Transplantation, Neovascularization, Pathologic, Phosphatidylinositol 3-Kinases, Phosphoinositide-3 Kinase Inhibitors, Phosphorylation, Proteins, Proto-Oncogene Proteins c-akt, Proto-Oncogene Proteins c-bcl-2, Repressor Proteins, Retinoblastoma Protein, Smad4 Protein, Survivin, Up-Regulation, Vascular Endothelial Growth Factor A, Wound Healing, Xenograft Model Antitumor Assays
Added April 12, 2016
0 Communities
1 Members
0 Resources
37 MeSH Terms
Comprehensive genetic analysis of cytarabine sensitivity in a cell-based model identifies polymorphisms associated with outcome in AML patients.
Gamazon ER, Lamba JK, Pounds S, Stark AL, Wheeler HE, Cao X, Im HK, Mitra AK, Rubnitz JE, Ribeiro RC, Raimondi S, Campana D, Crews KR, Wong SS, Welsh M, Hulur I, Gorsic L, Hartford CM, Zhang W, Cox NJ, Dolan ME
(2013) Blood 121: 4366-76
MeSH Terms: Antimetabolites, Antineoplastic, Apoptosis, Cytarabine, Drug Resistance, Neoplasm, Gene Expression Regulation, Leukemic, Genome-Wide Association Study, Genotype, Humans, Leukemia, Myeloid, Acute, Phenotype, Polymorphism, Single Nucleotide, Treatment Outcome
Added February 22, 2016
0 Communities
2 Members
0 Resources
12 MeSH Terms
Identification of novel germline polymorphisms governing capecitabine sensitivity.
O'Donnell PH, Stark AL, Gamazon ER, Wheeler HE, McIlwee BE, Gorsic L, Im HK, Huang RS, Cox NJ, Dolan ME
(2012) Cancer 118: 4063-73
MeSH Terms: Antimetabolites, Antineoplastic, Capecitabine, Deoxycytidine, Female, Fluorouracil, Genome-Wide Association Study, Humans, Male, Polymorphism, Single Nucleotide, Population Surveillance, Whites
Added February 22, 2016
0 Communities
2 Members
0 Resources
11 MeSH Terms
Systemic combination therapy of intravenous continuous 5-fluorouracil and subcutaneous pegylated interferon alfa-2a for advanced hepatocellular carcinoma.
Uchino K, Obi S, Tateishi R, Sato S, Kanda M, Sato T, Arano T, Enooku K, Goto E, Masuzaki R, Nakagawa H, Asaoka Y, Kondo Y, Yamashiki N, Goto T, Shiina S, Omata M, Yoshida H, Koike K
(2012) J Gastroenterol 47: 1152-9
MeSH Terms: Adult, Aged, Aged, 80 and over, Antimetabolites, Antineoplastic, Antineoplastic Combined Chemotherapy Protocols, Antiviral Agents, Carcinoma, Hepatocellular, Cohort Studies, Female, Fluorouracil, Humans, Infusions, Intravenous, Injections, Subcutaneous, Interferon-alpha, Japan, Liver Neoplasms, Male, Middle Aged, Polyethylene Glycols, Recombinant Proteins, Retrospective Studies, Survival Rate, Treatment Outcome
Added May 2, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms
A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303.
Innocenti F, Owzar K, Cox NL, Evans P, Kubo M, Zembutsu H, Jiang C, Hollis D, Mushiroda T, Li L, Friedman P, Wang L, Glubb D, Hurwitz H, Giacomini KM, McLeod HL, Goldberg RM, Schilsky RL, Kindler HL, Nakamura Y, Ratain MJ
(2012) Clin Cancer Res 18: 577-84
MeSH Terms: Adenocarcinoma, Aged, Amino Acid Substitution, Antimetabolites, Antineoplastic, Clinical Trials, Phase III as Topic, Deoxycytidine, Double-Blind Method, Female, Genome-Wide Association Study, Humans, Interleukin-17, Kaplan-Meier Estimate, Linkage Disequilibrium, Male, Middle Aged, Pancreatic Neoplasms, Polymorphism, Single Nucleotide, Randomized Controlled Trials as Topic
Added February 22, 2016
0 Communities
1 Members
0 Resources
18 MeSH Terms
One year survival with poorly differentiated metastatic pancreatic carcinoma following chemoembolization with gemcitabine and cisplatin.
Brown DB, Gonsalves CF, Yeo CJ, Witkiewicz AK, Carr BI
(2010) Oncol Rep 24: 767-9
MeSH Terms: Antimetabolites, Antineoplastic, Carcinoma, Pancreatic Ductal, Cell Differentiation, Chemoembolization, Therapeutic, Cisplatin, Deoxycytidine, Humans, Liver Neoplasms, Male, Middle Aged, Pancreatectomy, Pancreatic Neoplasms, Positron-Emission Tomography, Time Factors, Tomography, X-Ray Computed, Treatment Outcome
Added March 5, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Chemotherapy: Gemcitabine remains the standard of care for pancreatic cancer.
Berlin J, Benson AB
(2010) Nat Rev Clin Oncol 7: 135-7
MeSH Terms: Antimetabolites, Antineoplastic, Clinical Trials as Topic, Deoxycytidine, Humans, Pancreatic Neoplasms, Treatment Outcome
Added March 20, 2014
0 Communities
1 Members
0 Resources
6 MeSH Terms
Phase III, randomized study of gemcitabine and oxaliplatin versus gemcitabine (fixed-dose rate infusion) compared with gemcitabine (30-minute infusion) in patients with pancreatic carcinoma E6201: a trial of the Eastern Cooperative Oncology Group.
Poplin E, Feng Y, Berlin J, Rothenberg ML, Hochster H, Mitchell E, Alberts S, O'Dwyer P, Haller D, Catalano P, Cella D, Benson AB
(2009) J Clin Oncol 27: 3778-85
MeSH Terms: Adult, Aged, Antimetabolites, Antineoplastic, Antineoplastic Combined Chemotherapy Protocols, Deoxycytidine, Disease-Free Survival, Drug Administration Schedule, Female, Humans, Infusions, Intravenous, Kaplan-Meier Estimate, Male, Middle Aged, Organoplatinum Compounds, Oxaliplatin, Pancreatic Neoplasms, Treatment Outcome, United States
Added March 20, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms