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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 51

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Graphene oxide polarizes iNKT cells for production of TGFβ and attenuates inflammation in an iNKT cell-mediated sepsis model.
Lee SW, Park HJ, Van Kaer L, Hong S, Hong S
(2018) Sci Rep 8: 10081
MeSH Terms: Animals, Antigens, CD1d, Cell Polarity, Dendritic Cells, Disease Models, Animal, Galactosylceramides, Graphite, Humans, Inflammation, Intraepithelial Lymphocytes, Lymphocyte Activation, Mice, Nanotubes, Carbon, Natural Killer T-Cells, Sepsis, Toll-Like Receptor 4, Transforming Growth Factor beta
Added March 26, 2019
0 Communities
1 Members
0 Resources
17 MeSH Terms
Adipocyte-specific CD1d-deficiency mitigates diet-induced obesity and insulin resistance in mice.
Satoh M, Hoshino M, Fujita K, Iizuka M, Fujii S, Clingan CS, Van Kaer L, Iwabuchi K
(2016) Sci Rep 6: 28473
MeSH Terms: 3T3-L1 Cells, Adipocytes, Adiponectin, Animals, Antigen Presentation, Antigens, CD1d, B7-1 Antigen, Diet, High-Fat, Disease Models, Animal, Disease Progression, Galactosylceramides, Insulin Resistance, Interferon-gamma, Lymphocyte Activation, Macrophage Activation, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, Transgenic, Natural Killer T-Cells, Obesity
Added July 30, 2016
0 Communities
1 Members
0 Resources
21 MeSH Terms
Natural killer T cells in multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis.
Van Kaer L, Wu L, Parekh VV
(2015) Immunology 146: 1-10
MeSH Terms: Animals, Antigens, CD1d, Disease Models, Animal, Encephalomyelitis, Autoimmune, Experimental, Galactosylceramides, Humans, Immunotherapy, Lymphocyte Activation, Mice, Mice, Inbred C57BL, Multiple Sclerosis, Natural Killer T-Cells
Added September 28, 2015
0 Communities
2 Members
0 Resources
12 MeSH Terms
Specific deletion of LDL receptor-related protein on macrophages has skewed in vivo effects on cytokine production by invariant natural killer T cells.
Covarrubias R, Wilhelm AJ, Major AS
(2014) PLoS One 9: e102236
MeSH Terms: Adaptive Immunity, Animals, Antigens, CD1d, B-Lymphocytes, Cells, Cultured, Cytokines, Dendritic Cells, Gene Knockout Techniques, Immunoglobulin E, Low Density Lipoprotein Receptor-Related Protein-1, Lymphocyte Activation, Macrophages, Mice, Inbred C57BL, Mice, Knockout, Natural Killer T-Cells, Receptors, LDL, Tumor Suppressor Proteins
Added January 20, 2015
0 Communities
2 Members
0 Resources
17 MeSH Terms
Molecular signatures mostly associated with NK cells are predictive of relapse free survival in breast cancer patients.
Ascierto ML, Idowu MO, Zhao Y, Khalak H, Payne KK, Wang XY, Dumur CI, Bedognetti D, Tomei S, Ascierto PA, Shanker A, Bear HD, Wang E, Marincola FM, De Maria A, Manjili MH
(2013) J Transl Med 11: 145
MeSH Terms: Antigens, CD1d, Breast Neoplasms, Cell Adhesion Molecules, Cell Count, Disease-Free Survival, Female, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Humans, Killer Cells, Natural, Lymphocyte Activation, Lymphocyte Function-Associated Antigen-1, Neoplasm Recurrence, Local, Recurrence, Signal Transduction, Support Vector Machine, Treatment Outcome
Added March 7, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Invariant natural killer T cells as sensors and managers of inflammation.
Van Kaer L, Parekh VV, Wu L
(2013) Trends Immunol 34: 50-8
MeSH Terms: Animals, Antigens, CD1d, Humans, Immunotherapy, Infections, Inflammation, Lymphocyte Activation, Mice, Natural Killer T-Cells
Added March 7, 2014
0 Communities
2 Members
0 Resources
9 MeSH Terms
Natural killer T cells are required for lipopolysaccharide-mediated enhancement of atherosclerosis in apolipoprotein E-deficient mice.
Andoh Y, Ogura H, Satoh M, Shimano K, Okuno H, Fujii S, Ishimori N, Eshima K, Tamauchi H, Otani T, Nakai Y, Van Kaer L, Tsutsui H, Onoé K, Iwabuchi K
(2013) Immunobiology 218: 561-9
MeSH Terms: Animals, Antigens, CD1d, Apolipoproteins E, Atherosclerosis, Lipopolysaccharides, Lymphocyte Activation, Mice, Mice, Knockout, Natural Killer T-Cells
Added March 20, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms
Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice.
Wu L, Parekh VV, Gabriel CL, Bracy DP, Marks-Shulman PA, Tamboli RA, Kim S, Mendez-Fernandez YV, Besra GS, Lomenick JP, Williams B, Wasserman DH, Van Kaer L
(2012) Proc Natl Acad Sci U S A 109: E1143-52
MeSH Terms: Adipose Tissue, White, Animals, Antigens, CD1d, CD8-Positive T-Lymphocytes, Cells, Cultured, Cytokines, Dietary Fats, Fatty Liver, Female, Flow Cytometry, Galactosylceramides, Inflammation, Inflammation Mediators, Insulin Resistance, Lipids, Lymphocyte Activation, Macrophages, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Natural Killer T-Cells, Obesity
Added March 4, 2013
1 Communities
4 Members
0 Resources
23 MeSH Terms
Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands.
Florence WC, Xia C, Gordy LE, Chen W, Zhang Y, Scott-Browne J, Kinjo Y, Yu KO, Keshipeddy S, Pellicci DG, Patel O, Kjer-Nielsen L, McCluskey J, Godfrey DI, Rossjohn J, Richardson SK, Porcelli SA, Howell AR, Hayakawa K, Gapin L, Zajonc DM, Wang PG, Joyce S
(2009) EMBO J 28: 3579-90
MeSH Terms: Adaptation, Biological, Animals, Antigen Presentation, Antigens, CD1d, Antigens, Tumor-Associated, Carbohydrate, Cells, Cultured, Galactosylceramides, Ligands, Lymphocyte Activation, Mice, Mice, Inbred C57BL, Models, Molecular, Natural Killer T-Cells, Receptors, Antigen, T-Cell, Receptors, Antigen, T-Cell, alpha-beta, Structure-Activity Relationship, T-Cell Antigen Receptor Specificity
Added May 19, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Invariant natural killer T cells: innate-like T cells with potent immunomodulatory activities.
Wu L, Gabriel CL, Parekh VV, Van Kaer L
(2009) Tissue Antigens 73: 535-45
MeSH Terms: Animals, Antigen-Presenting Cells, Antigens, CD1d, Galactosylceramides, Glycolipids, Humans, Immunity, Innate, Immunotherapy, Lymphocyte Activation, Mice, Natural Killer T-Cells, Signal Transduction, T-Lymphocyte Subsets
Added December 10, 2013
0 Communities
2 Members
0 Resources
13 MeSH Terms