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Results: 1 to 4 of 4

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Dengue Virus prM-Specific Human Monoclonal Antibodies with Virus Replication-Enhancing Properties Recognize a Single Immunodominant Antigenic Site.
Smith SA, Nivarthi UK, de Alwis R, Kose N, Sapparapu G, Bombardi R, Kahle KM, Pfaff JM, Lieberman S, Doranz BJ, de Silva AM, Crowe JE
(2016) J Virol 90: 780-9
MeSH Terms: Antibodies, Monoclonal, Antibodies, Viral, Antibody-Dependent Enhancement, Dengue Virus, Epitope Mapping, Epitopes, Humans, Protein Binding, Viral Envelope Proteins, Virus Replication
Added January 26, 2016
0 Communities
1 Members
0 Resources
10 MeSH Terms
Spleen Tyrosine Kinase (Syk) Mediates IL-1β Induction by Primary Human Monocytes during Antibody-enhanced Dengue Virus Infection.
Callaway JB, Smith SA, McKinnon KP, de Silva AM, Crowe JE, Ting JP
(2015) J Biol Chem 290: 17306-20
MeSH Terms: Antibodies, Viral, Antibody-Dependent Enhancement, Antigen-Antibody Complex, Carrier Proteins, Caspase 1, Cells, Cultured, Dengue, Dengue Virus, Glyburide, Humans, Interleukin-1beta, Intracellular Signaling Peptides and Proteins, MAP Kinase Signaling System, Monocytes, NLR Family, Pyrin Domain-Containing 3 Protein, Protein-Tyrosine Kinases, RNA, Messenger, RNA, Small Interfering, Syk Kinase, Virus Replication
Added January 26, 2016
0 Communities
1 Members
0 Resources
20 MeSH Terms
Dengue viruses are enhanced by distinct populations of serotype cross-reactive antibodies in human immune sera.
de Alwis R, Williams KL, Schmid MA, Lai CY, Patel B, Smith SA, Crowe JE, Wang WK, Harris E, de Silva AM
(2014) PLoS Pathog 10: e1004386
MeSH Terms: Animals, Antibodies, Neutralizing, Antibodies, Viral, Antibody-Dependent Enhancement, Cross Reactions, Dengue Virus, Epitopes, Humans, Immune Sera, Mice, Neutralization Tests
Added February 2, 2015
0 Communities
1 Members
0 Resources
11 MeSH Terms
Human monoclonal antibodies derived from memory B cells following live attenuated dengue virus vaccination or natural infection exhibit similar characteristics.
Smith SA, de Alwis R, Kose N, Durbin AP, Whitehead SS, de Silva AM, Crowe JE
(2013) J Infect Dis 207: 1898-908
MeSH Terms: Antibodies, Monoclonal, Antibodies, Neutralizing, Antibodies, Viral, Antibody-Dependent Enhancement, Antigens, Viral, B-Lymphocytes, California, Cell Line, Cross Reactions, Dengue, Dengue Vaccines, Dengue Virus, Herpesvirus 4, Human, Humans, Hybridomas, Neutralization Tests, North Carolina, Recombinant Proteins, Vaccination, Vaccines, Attenuated
Added March 7, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms