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Results: 1 to 9 of 9

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Influenza Virus-Specific Human Antibody Repertoire Studies.
Crowe JE
(2019) J Immunol 202: 368-373
MeSH Terms: Antibodies, Viral, Antibody Diversity, Antigenic Variation, Antigens, Viral, B-Lymphocytes, Humans, Influenza A virus, Influenza Vaccines, Influenza, Human, Receptors, Antigen, B-Cell
Added March 31, 2019
0 Communities
1 Members
0 Resources
10 MeSH Terms
Increased breadth of HIV-1 neutralization achieved by diverse antibody clones each with limited neutralization breadth.
Chukwuma VU, Kose N, Sather DN, Sapparapu G, Falk R, King H, Singh V, Lampley R, Malherbe DC, Ditto NT, Sullivan JT, Barnes T, Doranz BJ, Labranche CC, Montefiori DC, Kalams SA, Haigwood NL, Crowe JE
(2018) PLoS One 13: e0209437
MeSH Terms: Antibodies, Neutralizing, Antibody Diversity, B-Lymphocytes, Cells, Cultured, Epitope Mapping, Epitopes, HIV Antibodies, HIV Infections, HIV-1, Humans, Hybridomas, Neutralization Tests, env Gene Products, Human Immunodeficiency Virus
Added March 31, 2019
0 Communities
1 Members
0 Resources
13 MeSH Terms
High-throughput antibody sequencing reveals genetic evidence of global regulation of the naïve and memory repertoires that extends across individuals.
Briney BS, Willis JR, McKinney BA, Crowe JE
(2012) Genes Immun 13: 469-73
MeSH Terms: Adult, Antibody Diversity, B-Lymphocyte Subsets, High-Throughput Nucleotide Sequencing, Humans, Immunoglobulin G, Immunoglobulin M, Immunologic Memory, V(D)J Recombination
Added August 6, 2012
0 Communities
1 Members
0 Resources
9 MeSH Terms
Multiple germline kappa light chains generate anti-insulin B cells in nonobese diabetic mice.
Woodward EJ, Thomas JW
(2005) J Immunol 175: 1073-9
MeSH Terms: Animals, Antibody Diversity, Autoantibodies, B-Lymphocyte Subsets, Base Sequence, Bone Marrow Cells, Gene Rearrangement, B-Lymphocyte, Light Chain, Genetic Predisposition to Disease, Immunoglobulin Variable Region, Immunoglobulin kappa-Chains, Insulin, Insulin Antibodies, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Inbred NOD, Mice, Transgenic, Molecular Sequence Data, Multigene Family, Polymorphism, Genetic, Protein Binding, Receptors, Antigen, B-Cell
Added November 6, 2013
2 Communities
1 Members
0 Resources
22 MeSH Terms
Infant and adult human B cell responses to rotavirus share common immunodominant variable gene repertoires.
Weitkamp JH, Kallewaard N, Kusuhara K, Bures E, Williams JV, LaFleur B, Greenberg HB, Crowe JE
(2003) J Immunol 171: 4680-8
MeSH Terms: Adult, Antibody Diversity, Antibody Specificity, B-Lymphocyte Subsets, Clone Cells, Complementarity Determining Regions, Female, Gene Rearrangement, B-Lymphocyte, Heavy Chain, Humans, Immunodominant Epitopes, Immunoglobulin Heavy Chains, Immunoglobulin J-Chains, Immunoglobulin Light Chains, Immunoglobulin Variable Region, Infant, Lymphocyte Count, Male, Protein Structure, Tertiary, Random Allocation, Rotavirus
Added February 27, 2014
0 Communities
2 Members
0 Resources
20 MeSH Terms
The natural autoantibody repertoire of nonobese diabetic mice is highly active.
Thomas JW, Kendall PL, Mitchell HG
(2002) J Immunol 169: 6617-24
MeSH Terms: Amino Acid Sequence, Animals, Antibodies, Antinuclear, Antibodies, Monoclonal, Antibody Diversity, Autoantibodies, Autoimmunity, B-Lymphocytes, Base Sequence, DNA, Diabetes Mellitus, Type 1, Female, Genes, Immunoglobulin, Hybridomas, Immunity, Innate, Insulin Antibodies, Male, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Inbred NOD, Molecular Sequence Data, Recombination, Genetic, Somatic Hypermutation, Immunoglobulin, Species Specificity
Added December 10, 2013
1 Communities
1 Members
0 Resources
25 MeSH Terms
Antigen-specific responses in autoimmunity and tolerance.
Thomas JW
(2001) Immunol Res 23: 235-44
MeSH Terms: Animals, Antibody Diversity, Autoantibodies, Autoantigens, Autoimmune Diseases, Autoimmunity, B-Lymphocyte Subsets, Clonal Anergy, Diabetes Mellitus, Experimental, Diabetes Mellitus, Type 1, Epitopes, Female, Fetal Macrosomia, Gene Rearrangement, B-Lymphocyte, Gene Silencing, Genes, Immunoglobulin, Humans, Immune Tolerance, Immunoglobulin Variable Region, Infant, Infant, Newborn, Insulin, Mice, Mice, Inbred BALB C, Mice, Inbred NOD, Mice, Transgenic, Models, Molecular, Osmolar Concentration, Pregnancy, Pregnancy in Diabetics, Protein Conformation, Transgenes
Added November 6, 2013
1 Communities
0 Members
0 Resources
32 MeSH Terms
Genetic and structural determinants of virus neutralizing antibodies.
Crowe JE, Suara RO, Brock S, Kallewaard N, House F, Weitkamp JH
(2001) Immunol Res 23: 135-45
MeSH Terms: Antibodies, Viral, Antibody Affinity, Antibody Diversity, Antigens, Viral, Cell Polarity, Epitopes, Evolution, Molecular, Genes, Immunoglobulin, Humans, Immunity, Innate, Immunoglobulin Fab Fragments, Immunoglobulin Isotypes, Immunoglobulin Variable Region, Immunologic Techniques, Mucous Membrane, Neutralization Tests, Respiratory Syncytial Viruses, Structure-Activity Relationship, Virion, Virus Replication
Added February 27, 2014
0 Communities
2 Members
0 Resources
20 MeSH Terms
V region diversity in human anti-insulin antibodies. Preferential use of a VHIII gene subset.
Thomas JW
(1993) J Immunol 150: 1375-82
MeSH Terms: Amino Acid Sequence, Antibody Diversity, Autoantibodies, Base Sequence, Diabetes Mellitus, Type 1, Gene Rearrangement, B-Lymphocyte, Heavy Chain, Genes, Immunoglobulin, Immunoglobulin Heavy Chains, Immunoglobulin Variable Region, Insulin, Molecular Sequence Data, Oligodeoxyribonucleotides, Polymerase Chain Reaction, Sequence Alignment
Added November 6, 2013
1 Communities
0 Members
0 Resources
14 MeSH Terms