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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 25

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Axonal organization defects in the hippocampus of adult conditional BACE1 knockout mice.
Ou-Yang MH, Kurz JE, Nomura T, Popovic J, Rajapaksha TW, Dong H, Contractor A, Chetkovich DM, Tourtellotte WG, Vassar R
(2018) Sci Transl Med 10:
MeSH Terms: Aging, Amyloid Precursor Protein Secretases, Animals, Animals, Newborn, Apoptosis, Aspartic Acid Endopeptidases, Axons, Cognition, Epilepsy, Gene Deletion, Hippocampus, Long-Term Potentiation, Memory Disorders, Mice, Inbred C57BL, Mice, Knockout, Myelin Sheath, Neurogenesis, Phenotype, Substrate Specificity
Added April 2, 2019
0 Communities
1 Members
0 Resources
19 MeSH Terms
Bexarotene Binds to the Amyloid Precursor Protein Transmembrane Domain, Alters Its α-Helical Conformation, and Inhibits γ-Secretase Nonselectively in Liposomes.
Kamp F, Scheidt HA, Winkler E, Basset G, Heinel H, Hutchison JM, LaPointe LM, Sanders CR, Steiner H, Huster D
(2018) ACS Chem Neurosci 9: 1702-1713
MeSH Terms: Amyloid Precursor Protein Secretases, Amyloid beta-Protein Precursor, Bexarotene, Cholesterol, HEK293 Cells, Humans, Liposomes, Molecular Structure, Neuroprotective Agents, Phosphatidylcholines, Protein Conformation, alpha-Helical, Protein Domains, Receptor, Notch1, Static Electricity
Added November 21, 2018
0 Communities
1 Members
0 Resources
14 MeSH Terms
Virulence factors enhance Citrobacter rodentium expansion through aerobic respiration.
Lopez CA, Miller BM, Rivera-Chávez F, Velazquez EM, Byndloss MX, Chávez-Arroyo A, Lokken KL, Tsolis RM, Winter SE, Bäumler AJ
(2016) Science 353: 1249-53
MeSH Terms: Aerobiosis, Amyloid Precursor Protein Secretases, Animals, Citrobacter rodentium, Colitis, Colon, Cytochromes, Dibenzazepines, Electron Transport Chain Complex Proteins, Enterobacteriaceae Infections, Gene Deletion, Hyperplasia, Intestinal Mucosa, Ki-67 Antigen, Mice, Mice, Inbred C3H, Mice, Inbred C57BL, Nitrates, Oxidoreductases, Receptors, Notch, Virulence Factors
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
How γ-secretase hits a moving target.
Sanders CR
(2016) Elife 5:
MeSH Terms: Alzheimer Disease, Amyloid Precursor Protein Secretases, Amyloid beta-Peptides, Amyloid beta-Protein Precursor, Endopeptidases, Humans
Added November 21, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Transthyretin Suppresses Amyloid-β Secretion by Interfering with Processing of the Amyloid-β Protein Precursor.
Li X, Song Y, Sanders CR, Buxbaum JN
(2016) J Alzheimers Dis 52: 1263-75
MeSH Terms: Alzheimer Disease, Amyloid Precursor Protein Secretases, Amyloid beta-Peptides, Amyloid beta-Protein Precursor, Animals, Brain, CHO Cells, Cricetulus, Enzyme-Linked Immunosorbent Assay, Female, Immunoprecipitation, Male, Mice, Mice, Transgenic, Prealbumin
Added November 21, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Deleting the TGF-β receptor in proximal tubules impairs HGF signaling.
Nlandu Khodo S, Neelisetty S, Woodbury L, Green E, Harris RC, Zent R, Gewin L
(2016) Am J Physiol Renal Physiol 310: F499-510
MeSH Terms: Amyloid Precursor Protein Secretases, Animals, Cells, Cultured, Hepatocyte Growth Factor, Kidney Tubules, Proximal, Mice, Protein-Serine-Threonine Kinases, Proto-Oncogene Proteins c-met, Receptor, Transforming Growth Factor-beta Type II, Receptors, Notch, Receptors, Transforming Growth Factor beta, Signal Transduction, Transforming Growth Factor beta
Added January 29, 2016
1 Communities
3 Members
0 Resources
13 MeSH Terms
Differential proteomic and behavioral effects of long-term voluntary exercise in wild-type and APP-overexpressing transgenics.
Rao SK, Ross JM, Harrison FE, Bernardo A, Reiserer RS, Reiserer RS, Mobley JA, McDonald MP
(2015) Neurobiol Dis 78: 45-55
MeSH Terms: Alzheimer Disease, Amyloid Precursor Protein Secretases, Amyloid beta-Protein Precursor, Animals, Aspartic Acid Endopeptidases, Behavior, Animal, Hippocampus, Mice, Mice, Transgenic, Motor Activity, Presenilin-1, Proteomics, Spatial Memory
Added May 11, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms
The transcriptional corepressor MTGR1 regulates intestinal secretory lineage allocation.
Parang B, Rosenblatt D, Williams AD, Washington MK, Revetta F, Short SP, Reddy VK, Hunt A, Shroyer NF, Engel ME, Hiebert SW, Williams CS
(2015) FASEB J 29: 786-95
MeSH Terms: Amyloid Precursor Protein Secretases, Animals, Apoptosis, Blotting, Western, Cell Differentiation, Cell Lineage, Cell Proliferation, Cells, Cultured, Epithelial Cells, Flow Cytometry, Immunoenzyme Techniques, Immunoprecipitation, Intestinal Mucosa, Intestines, Mice, Mice, Knockout, Paneth Cells, Protease Inhibitors, RNA, Messenger, Real-Time Polymerase Chain Reaction, Receptors, Notch, Repressor Proteins, Reverse Transcriptase Polymerase Chain Reaction
Added December 8, 2014
1 Communities
4 Members
0 Resources
23 MeSH Terms
p75 neurotrophin receptor cleavage by α- and γ-secretases is required for neurotrophin-mediated proliferation of brain tumor-initiating cells.
Forsyth PA, Krishna N, Lawn S, Valadez JG, Qu X, Fenstermacher DA, Fournier M, Potthast L, Chinnaiyan P, Gibney GT, Zeinieh M, Barker PA, Carter BD, Cooper MK, Kenchappa RS
(2014) J Biol Chem 289: 8067-85
MeSH Terms: Amyloid Precursor Protein Secretases, Brain, Brain Neoplasms, Cell Line, Tumor, Cell Proliferation, Gene Knockdown Techniques, Glioma, Humans, Mutation, Neoplastic Stem Cells, Nerve Growth Factors, Receptor, Nerve Growth Factor
Added March 17, 2014
0 Communities
2 Members
0 Resources
12 MeSH Terms
Receptor tyrosine kinases in the nucleus.
Carpenter G, Liao HJ
(2013) Cold Spring Harb Perspect Biol 5: a008979
MeSH Terms: Active Transport, Cell Nucleus, Amyloid Precursor Protein Secretases, Cell Nucleus, Models, Biological, Nuclear Localization Signals, Peptide Fragments, Protein Structure, Tertiary, Receptor Protein-Tyrosine Kinases
Added March 7, 2014
0 Communities
1 Members
0 Resources
8 MeSH Terms