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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 12

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The Structure of the Bifunctional Everninomicin Biosynthetic Enzyme EvdMO1 Suggests Independent Activity of the Fused Methyltransferase-Oxidase Domains.
Starbird CA, Perry NA, Chen Q, Berndt S, Yamakawa I, Loukachevitch LV, Limbrick EM, Bachmann BO, Iverson TM, McCulloch KM
(2018) Biochemistry 57: 6827-6837
MeSH Terms: Amino Acid Sequence, Aminoglycosides, Bacterial Proteins, Biosynthetic Pathways, Catalytic Domain, Conserved Sequence, Crystallography, X-Ray, Gene Fusion, Genes, Bacterial, Methyltransferases, Micromonospora, Models, Molecular, Oxygenases, Protein Interaction Domains and Motifs, Sequence Homology, Amino Acid
Added April 1, 2019
0 Communities
1 Members
0 Resources
15 MeSH Terms
Oxidative cyclizations in orthosomycin biosynthesis expand the known chemistry of an oxygenase superfamily.
McCulloch KM, McCranie EK, Smith JA, Sarwar M, Mathieu JL, Gitschlag BL, Du Y, Bachmann BO, Iverson TM
(2015) Proc Natl Acad Sci U S A 112: 11547-52
MeSH Terms: Aminoglycosides, Anti-Bacterial Agents, Catalytic Domain, Crystallography, X-Ray, Cyclization, Hydrogen, Hygromycin B, Metals, Micromonospora, Multigene Family, Oligosaccharides, Open Reading Frames, Oxidation-Reduction, Oxygen, Oxygenases, Phylogeny, Protein Binding, Protein Structure, Secondary, Reproducibility of Results, Streptomyces
Added April 1, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Nikkomycin Z is an effective inhibitor of the chytrid fungus linked to global amphibian declines.
Holden WM, Fites JS, Reinert LK, Rollins-Smith LA
(2014) Fungal Biol 118: 48-60
MeSH Terms: Aminoglycosides, Amphibians, Animals, Antifungal Agents, Cell Wall, Chytridiomycota
Added May 20, 2014
0 Communities
1 Members
0 Resources
6 MeSH Terms
The invasive chytrid fungus of amphibians paralyzes lymphocyte responses.
Fites JS, Ramsey JP, Holden WM, Collier SP, Sutherland DM, Reinert LK, Gayek AS, Dermody TS, Aune TM, Oswald-Richter K, Rollins-Smith LA
(2013) Science 342: 366-9
MeSH Terms: Aminoglycosides, Amphibians, Animals, Apoptosis, Cell Proliferation, Chytridiomycota, Host-Pathogen Interactions, Lymphocytes, Mycoses, Spores, Fungal, Xenopus laevis
Added March 7, 2014
0 Communities
4 Members
0 Resources
11 MeSH Terms
The GABRG2 nonsense mutation, Q40X, associated with Dravet syndrome activated NMD and generated a truncated subunit that was partially rescued by aminoglycoside-induced stop codon read-through.
Huang X, Tian M, Hernandez CC, Hu N, Macdonald RL
(2012) Neurobiol Dis 48: 115-23
MeSH Terms: Aminoglycosides, Codon, Nonsense, Codon, Terminator, Epilepsies, Myoclonic, HEK293 Cells, Humans, Nonsense Mediated mRNA Decay, Protein Subunits, Receptors, GABA-A
Added January 24, 2015
0 Communities
1 Members
0 Resources
9 MeSH Terms
Acute kidney injury after placement of an antibiotic-impregnated cement spacer during revision total knee arthroplasty.
Menge TJ, Koethe JR, Jenkins CA, Wright PW, Shinar AA, Miller GG, Holt GE
(2012) J Arthroplasty 27: 1221-7.e1-2
MeSH Terms: Acute Kidney Injury, Aged, Aminoglycosides, Anti-Bacterial Agents, Arthroplasty, Replacement, Knee, Bone Cements, Cohort Studies, Creatinine, Female, Humans, Incidence, Kidney, Knee Prosthesis, Male, Middle Aged, Prosthesis-Related Infections, Reoperation, Retrospective Studies, Tobramycin
Added May 27, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms
Adopting real-time surveillance dashboards as a component of an enterprisewide medication safety strategy.
Waitman LR, Phillips IE, McCoy AB, Danciu I, Halpenny RM, Nelsen CL, Johnson DC, Starmer JM, Peterson JF
(2011) Jt Comm J Qual Patient Saf 37: 326-32
MeSH Terms: Aminoglycosides, Anticoagulants, Communication, Decision Support Systems, Clinical, Humans, Medical Records Systems, Computerized, Medication Errors, Pharmacy Service, Hospital, Safety Management
Added May 19, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms
Transcripts from a novel BMPR2 termination mutation escape nonsense mediated decay by downstream translation re-initiation: implications for treating pulmonary hypertension.
Hamid R, Hedges LK, Austin E, Phillips JA, Loyd JE, Cogan JD
(2010) Clin Genet 77: 280-6
MeSH Terms: Aminoglycosides, Bone Morphogenetic Protein Receptors, Type II, Codon, Nonsense, Female, Humans, Hypertension, Pulmonary, Lymphocytes, Male, Mutation, Pedigree
Added March 5, 2014
0 Communities
3 Members
0 Resources
10 MeSH Terms
Activation of the DNA-dependent protein kinase by drug-induced and radiation-induced DNA strand breaks.
MÃ¥rtensson S, Nygren J, Osheroff N, Hammarsten O
(2003) Radiat Res 160: 291-301
MeSH Terms: Aminoglycosides, Anti-Bacterial Agents, Antibiotics, Antineoplastic, Antigens, Nuclear, Antimetabolites, Antineoplastic, Bleomycin, DNA, DNA Damage, DNA Helicases, DNA Repair, DNA Topoisomerases, Type II, DNA-Activated Protein Kinase, DNA-Binding Proteins, Dose-Response Relationship, Drug, Enediynes, Energy Transfer, Enzyme Activation, Etoposide, Ferritins, Ku Autoantigen, Models, Biological, Nucleic Acid Synthesis Inhibitors, Plasmids, Protein Binding, Protein-Serine-Threonine Kinases, Radiation, Ionizing
Added March 5, 2014
0 Communities
1 Members
0 Resources
26 MeSH Terms
Discovery of aminoglycoside mimetics by NMR-based screening of Escherichia coli A-site RNA.
Yu L, Oost TK, Schkeryantz JM, Yang J, Janowick D, Fesik SW
(2003) J Am Chem Soc 125: 4444-50
MeSH Terms: Aminoglycosides, Aminoquinolines, Anti-Bacterial Agents, Binding, Competitive, Biomimetic Materials, Escherichia coli, Ligands, Models, Molecular, Nuclear Magnetic Resonance, Biomolecular, RNA, Bacterial, RNA, Ribosomal, 16S
Added March 5, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms