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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 23

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Mechanism of Hyperkalemia-Induced Metabolic Acidosis.
Harris AN, Grimm PR, Lee HW, Delpire E, Fang L, Verlander JW, Welling PA, Weiner ID
(2018) J Am Soc Nephrol 29: 1411-1425
MeSH Terms: Acidosis, Aldosterone, Amiloride, Ammonia, Animals, Cation Transport Proteins, Diuretics, Glutaminase, Hydrochlorothiazide, Hydrogen-Ion Concentration, Hyperkalemia, Kidney Tubules, Distal, Kidney Tubules, Proximal, Membrane Glycoproteins, Mice, Mice, Knockout, Protein-Serine-Threonine Kinases, Proton-Translocating ATPases, Urinalysis
Added April 3, 2018
0 Communities
1 Members
0 Resources
19 MeSH Terms
Dendritic Cell Amiloride-Sensitive Channels Mediate Sodium-Induced Inflammation and Hypertension.
Barbaro NR, Foss JD, Kryshtal DO, Tsyba N, Kumaresan S, Xiao L, Mernaugh RL, Itani HA, Loperena R, Chen W, Dikalov S, Titze JM, Knollmann BC, Harrison DG, Kirabo A
(2017) Cell Rep 21: 1009-1020
MeSH Terms: Amiloride, Animals, Cells, Cultured, Cytokines, Dendritic Cells, Epithelial Sodium Channel Blockers, Epithelial Sodium Channels, Hypertension, Inflammation, Male, Mice, Mice, Inbred C57BL, NADPH Oxidases, Oxidative Stress, Prostaglandins E, Protein Kinase C, Sodium, Sodium-Hydrogen Exchanger 1, Superoxides
Added December 27, 2017
0 Communities
2 Members
0 Resources
19 MeSH Terms
Integrated compensatory network is activated in the absence of NCC phosphorylation.
Grimm PR, Lazo-Fernandez Y, Delpire E, Wall SM, Dorsey SG, Weinman EJ, Coleman R, Wade JB, Welling PA
(2015) J Clin Invest 125: 2136-50
MeSH Terms: Amiloride, Ammonia, Animals, Biological Transport, Blood Pressure, Carbonic Anhydrases, Chlorides, Disease Models, Animal, Enzyme Activation, Epithelial Sodium Channels, Gene Expression Profiling, Gene Regulatory Networks, Gitelman Syndrome, Ketoglutaric Acids, Kidney Glomerulus, Male, Mice, Mice, Knockout, Natriuresis, Nephrons, Paracrine Communication, Phosphorylation, Protein Processing, Post-Translational, Protein-Serine-Threonine Kinases, Receptors, Notch, Receptors, Purinergic P2, Renal Reabsorption, Signal Transduction, Sodium Chloride, Sodium-Potassium-Chloride Symporters, Solute Carrier Family 12, Member 3
Added May 3, 2017
0 Communities
1 Members
0 Resources
31 MeSH Terms
Nitric oxide reduces Cl⁻ absorption in the mouse cortical collecting duct through an ENaC-dependent mechanism.
Pech V, Thumova M, Dikalov SI, Hummler E, Rossier BC, Harrison DG, Wall SM
(2013) Am J Physiol Renal Physiol 304: F1390-7
MeSH Terms: Absorption, Aldosterone, Amiloride, Angiotensin II, Animals, Anion Transport Proteins, Chloride-Bicarbonate Antiporters, Chlorides, Epithelial Sodium Channels, Female, In Vitro Techniques, Kidney Tubules, Collecting, Male, Mice, Mice, Knockout, NG-Nitroarginine Methyl Ester, Nitric Oxide, Nitric Oxide Donors, Nitric Oxide Synthase, Sodium, Sulfate Transporters
Added March 31, 2015
1 Communities
2 Members
0 Resources
21 MeSH Terms
A two-hit mechanism for sepsis-induced impairment of renal tubule function.
Watts BA, George T, Sherwood ER, Good DW
(2013) Am J Physiol Renal Physiol 304: F863-74
MeSH Terms: Absorption, Aldosterone, Amiloride, Animals, Bicarbonates, Cecum, Extracellular Signal-Regulated MAP Kinases, Flavonoids, Kidney Tubules, Ligation, Lipopolysaccharides, Loop of Henle, Mice, Mice, Inbred C57BL, Sepsis, Toll-Like Receptor 4, Up-Regulation
Added October 18, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms
Blockade of insect odorant receptor currents by amiloride derivatives.
Pask GM, Bobkov YV, Corey EA, Ache BW, Zwiebel LJ
(2013) Chem Senses 38: 221-9
MeSH Terms: Amiloride, Animals, Anopheles, Cell Line, HEK293 Cells, Humans, Insect Proteins, Patch-Clamp Techniques, Receptors, Odorant, Thioglycolates, Transfection, Triazoles
Added May 27, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Dimethyl amiloride improves glucose homeostasis in mouse models of type 2 diabetes.
Gunawardana SC, Head WS, Piston DW
(2008) Am J Physiol Endocrinol Metab 294: E1097-108
MeSH Terms: Amiloride, Amino Acids, Cyclic, Animals, Arginine, Blood Glucose, Diabetes Mellitus, Type 2, Disease Models, Animal, Drug Synergism, Homeostasis, Hydrogen-Ion Concentration, Insulin, Insulin Secretion, Insulin-Secreting Cells, Keto Acids, Ketoglutarate Dehydrogenase Complex, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Mitochondria, NG-Nitroarginine Methyl Ester, Nitric Oxide Synthase Type I, Sodium-Calcium Exchanger
Added November 1, 2012
0 Communities
1 Members
0 Resources
23 MeSH Terms
Central receptors mediating the cardiovascular actions of melanocyte stimulating hormones.
Ni XP, Butler AA, Cone RD, Humphreys MH
(2006) J Hypertens 24: 2239-46
MeSH Terms: Amiloride, Animals, Blood Pressure, Dose-Response Relationship, Drug, Heart Rate, Hypertension, Mice, Mice, Knockout, Models, Animal, Receptor, Melanocortin, Type 3, Receptor, Melanocortin, Type 4, Sodium Channel Blockers, Sympatholytics, alpha-MSH, gamma-MSH
Added December 10, 2013
0 Communities
1 Members
0 Resources
15 MeSH Terms
Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel.
Nakagawa K, Holla VR, Wei Y, Wang WH, Gatica A, Wei S, Mei S, Miller CM, Cha DR, Price E, Zent R, Pozzi A, Breyer MD, Guan Y, Falck JR, Waterman MR, Capdevila JH
(2006) J Clin Invest 116: 1696-702
MeSH Terms: Amiloride, Animals, Arachidonic Acids, Blood Pressure, Cytochrome P-450 Enzyme System, Cytochrome P450 Family 2, Electrophysiology, Epithelial Sodium Channels, Female, Humans, Hypertension, Kidney, Male, Mice, Mice, Knockout, Pyrimidines, Sodium, Sodium Channel Blockers, Sodium Channels, Sodium, Dietary
Added February 24, 2014
2 Communities
4 Members
0 Resources
20 MeSH Terms
Thiazolidinediones expand body fluid volume through PPARgamma stimulation of ENaC-mediated renal salt absorption.
Guan Y, Hao C, Cha DR, Rao R, Lu W, Kohan DE, Magnuson MA, Redha R, Zhang Y, Breyer MD
(2005) Nat Med 11: 861-6
MeSH Terms: Amiloride, Analysis of Variance, Animals, Blood Chemical Analysis, Body Fluids, Body Weight, Chromatin Immunoprecipitation, Diabetes Mellitus, Type 2, Epithelial Sodium Channels, Gene Targeting, Mice, Mice, Transgenic, Nephrons, PPAR gamma, Reverse Transcriptase Polymerase Chain Reaction, Sodium, Sodium Channels, Thiazolidinediones, Water-Electrolyte Balance
Added September 9, 2013
1 Communities
1 Members
1 Resources
19 MeSH Terms