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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 14

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Genome-Wide Association and Functional Studies Reveal Novel Pharmacological Mechanisms for Allopurinol.
Brackman DJ, Yee SW, Enogieru OJ, Shaffer C, Ranatunga D, Denny JC, Wei WQ, Kamatani Y, Kubo M, Roden DM, Jorgenson E, Giacomini KM
(2019) Clin Pharmacol Ther 106: 623-631
MeSH Terms: ATP Binding Cassette Transporter, Subfamily G, Member 2, Aged, Aged, 80 and over, Allopurinol, Cytokines, Ethnic Groups, Female, Genome-Wide Association Study, Glucose Transport Proteins, Facilitative, Humans, Male, Middle Aged, Neoplasm Proteins, Oxypurinol, Prognosis, Uric Acid
Added March 24, 2020
0 Communities
1 Members
0 Resources
16 MeSH Terms
NEW STRATEGIES TO PREDICT AND PREVENT SERIOUS IMMUNOLOGICALLY MEDIATED ADVERSE DRUG REACTIONS.
Phillips EJ
(2018) Trans Am Clin Climatol Assoc 129: 74-87
MeSH Terms: Aged, Allopurinol, Animals, Drug Eruptions, Drug Hypersensitivity, Drug-Related Side Effects and Adverse Reactions, Female, Genetic Predisposition to Disease, Gout Suppressants, HLA Antigens, Humans, Lymphocyte Activation, Phenotype, Receptors, Antigen, T-Cell, Risk Assessment, Risk Factors, T-Lymphocytes
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Recent advances in the understanding of severe cutaneous adverse reactions.
Adler NR, Aung AK, Ergen EN, Trubiano J, Goh MSY, Phillips EJ
(2017) Br J Dermatol 177: 1234-1247
MeSH Terms: Allopurinol, Anticonvulsants, Carbamazepine, Cephalosporins, Dideoxynucleosides, Drug Eruptions, Drug Interactions, Herpesviridae Infections, Humans, Leukocytes, Mononuclear, Pharmacogenetics, Prospective Studies, Skin Tests, T-Lymphocytes, Virus Activation, Virus Latency, beta-Lactams
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Moderating effects of immunosuppressive medications and risk factors for post-operative joint infection following total joint arthroplasty in patients with rheumatoid arthritis or osteoarthritis.
Salt E, Wiggins AT, Rayens MK, Morris BJ, Mannino D, Hoellein A, Donegan RP, Crofford LJ
(2017) Semin Arthritis Rheum 46: 423-429
MeSH Terms: Aged, Allopurinol, Arthritis, Rheumatoid, Arthroplasty, Replacement, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Shoulder, Case-Control Studies, Comorbidity, Diabetes Mellitus, Female, Glucocorticoids, Gout, Gout Suppressants, HIV Infections, Humans, Immunologic Deficiency Syndromes, Immunosuppressive Agents, Logistic Models, Lupus Erythematosus, Systemic, Male, Middle Aged, Multivariate Analysis, Neoplasms, Obesity, Osteoarthritis, Osteoarthritis, Hip, Osteoarthritis, Knee, Prednisone, Prosthesis-Related Infections, Retrospective Studies, Risk Factors, Sex Factors, Shoulder Joint, Surgical Wound Infection
Added March 25, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Evolving models of the immunopathogenesis of T cell-mediated drug allergy: The role of host, pathogens, and drug response.
White KD, Chung WH, Hung SI, Mallal S, Phillips EJ
(2015) J Allergy Clin Immunol 136: 219-34; quiz 235
MeSH Terms: Allopurinol, B-Lymphocytes, Carbamazepine, Dideoxynucleosides, Drug Hypersensitivity, Gene Expression Regulation, Genetic Loci, HLA Antigens, Humans, Models, Immunological, Pharmacogenetics, Stevens-Johnson Syndrome, T-Lymphocytes, Virus Diseases
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for human leukocyte antigen B (HLA-B) genotype and allopurinol dosing: 2015 update.
Saito Y, Stamp LK, Caudle KE, Hershfield MS, McDonagh EM, Callaghan JT, Tassaneeyakul W, Mushiroda T, Kamatani N, Goldspiel BR, Phillips EJ, Klein TE, Lee MT, Clinical Pharmacogenetics Implementation Consortium
(2016) Clin Pharmacol Ther 99: 36-7
MeSH Terms: Allopurinol, Biomarkers, Pharmacological, Drug Administration Schedule, Genotype, Guidelines as Topic, HLA-B Antigens, Humans
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Genotyping for severe drug hypersensitivity.
Karlin E, Phillips E
(2014) Curr Allergy Asthma Rep 14: 418
MeSH Terms: Allopurinol, Amoxicillin-Potassium Clavulanate Combination, Carbamazepine, Dideoxynucleosides, Drug Hypersensitivity, Genotype, HLA-B Antigens, Humans, Nevirapine, Pharmacogenetics, Protein Conformation, Stevens-Johnson Syndrome
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
UW solution improved with high anti-apoptotic activity by S-nitrosated human serum albumin.
Ishima Y, Shinagawa T, Yoneshige S, Kragh-Hansen U, Ohya Y, Inomata Y, Kai T, Otagiri M, Maruyama T
(2013) Nitric Oxide 30: 36-42
MeSH Terms: Adenosine, Allopurinol, Analysis of Variance, Animals, Apoptosis, Glutathione, Hep G2 Cells, Humans, Insulin, Liver, Liver Diseases, Liver Transplantation, Male, Necrosis, Nitric Oxide Donors, Nitroso Compounds, Organ Preservation Solutions, Raffinose, Rats, Rats, Wistar, Reperfusion Injury, Serum Albumin, Serum Albumin, Human
Added February 11, 2015
0 Communities
1 Members
0 Resources
23 MeSH Terms
The role of aldehyde oxidase and xanthine oxidase in the biotransformation of a novel negative allosteric modulator of metabotropic glutamate receptor subtype 5.
Morrison RD, Blobaum AL, Byers FW, Santomango TS, Bridges TM, Stec D, Brewer KA, Sanchez-Ponce R, Corlew MM, Rush R, Felts AS, Manka J, Bates BS, Venable DF, Rodriguez AL, Jones CK, Niswender CM, Conn PJ, Lindsley CW, Emmitte KA, Daniels JS
(2012) Drug Metab Dispos 40: 1834-45
MeSH Terms: Aldehyde Oxidase, Allopurinol, Animals, Benzamides, Biotransformation, Chromatography, Liquid, Enzyme Inhibitors, Excitatory Amino Acid Antagonists, Hepatocytes, Humans, Hydroxylation, Injections, Intravenous, Liver, Macaca fascicularis, Magnetic Resonance Spectroscopy, Male, Metabolic Clearance Rate, Microsomes, Liver, Models, Biological, Molecular Structure, Oxygen Isotopes, Raloxifene Hydrochloride, Rats, Rats, Sprague-Dawley, Receptor, Metabotropic Glutamate 5, Receptors, Metabotropic Glutamate, Species Specificity, Tandem Mass Spectrometry, Thiazoles, Xanthine Oxidase
Added March 7, 2014
1 Communities
5 Members
0 Resources
30 MeSH Terms
Initiating allopurinol therapy: do we need to know the patient's human leucocyte antigen status?
Lee MH, Stocker SL, Anderson J, Phillips EJ, Nolan D, Williams KM, Graham GG, Sullivan JR, Day RO
(2012) Intern Med J 42: 411-6
MeSH Terms: Adult, Aged, Aged, 80 and over, Allopurinol, Asian Continental Ancestry Group, Australia, Drug Hypersensitivity, Female, Genetic Predisposition to Disease, HLA Antigens, HLA-B Antigens, Humans, Male, Middle Aged, Stevens-Johnson Syndrome
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms