Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 10 of 20

Publication Record

Connections

Control of antiviral innate immune response by protein geranylgeranylation.
Yang S, Harding AT, Sweeney C, Miao D, Swan G, Zhou C, Jiang Z, Fitzgerald KA, Hammer G, Bergo MO, Kroh HK, Lacy DB, Sun C, Glogauer M, Que LG, Heaton NS, Wang D
(2019) Sci Adv 5: eaav7999
MeSH Terms: Adaptor Proteins, Signal Transducing, Alkyl and Aryl Transferases, Animals, Endoplasmic Reticulum, Female, Humans, Immunity, Innate, Macrophages, Alveolar, Male, Mice, Knockout, Neuropeptides, Orthomyxoviridae Infections, Protein Prenylation, Receptor-Interacting Protein Serine-Threonine Kinases, Tripartite Motif Proteins, Ubiquitin-Protein Ligases, rac GTP-Binding Proteins, rac1 GTP-Binding Protein
Added March 24, 2020
0 Communities
1 Members
0 Resources
18 MeSH Terms
Pharmacological characterization, structural studies, and in vivo activities of anti-Chagas disease lead compounds derived from tipifarnib.
Buckner FS, Bahia MT, Suryadevara PK, White KL, Shackleford DM, Chennamaneni NK, Hulverson MA, Laydbak JU, Chatelain E, Scandale I, Verlinde CL, Charman SA, Lepesheva GI, Gelb MH
(2012) Antimicrob Agents Chemother 56: 4914-21
MeSH Terms: 14-alpha Demethylase Inhibitors, Administration, Oral, Alkyl and Aryl Transferases, Animals, Chagas Disease, Crystallography, X-Ray, Cytochrome P-450 Enzyme Inhibitors, Cytochrome P-450 Enzyme System, Drug Administration Schedule, Female, Humans, Mice, Models, Molecular, Nitroimidazoles, Quinolones, Structure-Activity Relationship, Triazoles, Trypanocidal Agents, Trypanosoma cruzi
Added July 2, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Investigating conservation of the albaflavenone biosynthetic pathway and CYP170 bifunctionality in streptomycetes.
Moody SC, Zhao B, Lei L, Nelson DR, Mullins JG, Waterman MR, Kelly SL, Lamb DC
(2012) FEBS J 279: 1640-9
MeSH Terms: Alkyl and Aryl Transferases, Amino Acid Sequence, Catalytic Domain, Cytochrome P-450 Enzyme System, Models, Molecular, Molecular Sequence Data, Polyisoprenyl Phosphates, Sesquiterpenes, Streptomyces, Streptomyces coelicolor
Added February 12, 2015
0 Communities
1 Members
0 Resources
10 MeSH Terms
Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates.
Noel JP, Dellas N, Faraldos JA, Zhao M, Hess BA, Smentek L, Coates RM, O'Maille PE
(2010) ACS Chem Biol 5: 377-92
MeSH Terms: Alkyl and Aryl Transferases, Crystallography, X-Ray, Cyclization, Models, Molecular, Mutation, Polyisoprenyl Phosphates, Sesquiterpenes, Stereoisomerism, Substrate Specificity, Tobacco
Added February 15, 2016
0 Communities
1 Members
0 Resources
10 MeSH Terms
Crystal structure of albaflavenone monooxygenase containing a moonlighting terpene synthase active site.
Zhao B, Lei L, Vassylyev DG, Lin X, Cane DE, Kelly SL, Yuan H, Lamb DC, Waterman MR
(2009) J Biol Chem 284: 36711-36719
MeSH Terms: Alkyl and Aryl Transferases, Bacterial Proteins, Catalytic Domain, Crystallography, X-Ray, Cytochrome P-450 Enzyme System, Heme, Iron, Polyisoprenyl Phosphates, Protein Binding, Protein Structure, Secondary, Protein Structure, Tertiary, Sesquiterpenes, Streptomyces coelicolor
Added February 12, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms
Novel variants at KCTD10, MVK, and MMAB genes interact with dietary carbohydrates to modulate HDL-cholesterol concentrations in the Genetics of Lipid Lowering Drugs and Diet Network Study.
Junyent M, Parnell LD, Lai CQ, Lee YC, Smith CE, Arnett DK, Tsai MY, Kabagambe EK, Straka RJ, Province M, An P, Borecki I, Ordovás JM
(2009) Am J Clin Nutr 90: 686-94
MeSH Terms: Adult, Aged, Alkyl and Aryl Transferases, Cholesterol, HDL, Diet, Diet Surveys, Dietary Carbohydrates, Epigenesis, Genetic, Female, Genome-Wide Association Study, Humans, Hyperlipidemias, Male, Middle Aged, Phosphotransferases (Alcohol Group Acceptor), Polymorphism, Single Nucleotide, Potassium Channels, Voltage-Gated, Sex Factors
Added April 23, 2015
0 Communities
1 Members
0 Resources
18 MeSH Terms
The bis-electrophile diepoxybutane cross-links DNA to human histones but does not result in enhanced mutagenesis in recombinant systems.
Loecken EM, Dasari S, Hill S, Tabb DL, Guengerich FP
(2009) Chem Res Toxicol 22: 1069-76
MeSH Terms: Alkyl and Aryl Transferases, Cross-Linking Reagents, DNA, Epoxy Compounds, Histones, Humans, Mutagenesis, Mutagens, Peptide Fragments, Recombinant Proteins
Added March 5, 2014
0 Communities
2 Members
0 Resources
10 MeSH Terms
A novel homozygous SCO2 mutation, p.G193S, causing fatal infantile cardioencephalomyopathy.
Mobley BC, Enns GM, Wong LJ, Vogel H
(2009) Clin Neuropathol 28: 143-9
MeSH Terms: Alkyl and Aryl Transferases, Base Sequence, Cardiomyopathies, Carrier Proteins, Consanguinity, Electron Transport, Electron Transport Complex IV, Fatal Outcome, Female, Humans, Infant, Newborn, Male, Membrane Proteins, Mitochondrial Encephalomyopathies, Mitochondrial Proteins, Molecular Chaperones, Molecular Sequence Data, Muscle, Skeletal, Mutation, Pedigree, Sequence Homology, Nucleic Acid
Added August 14, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms
Rational modification of a candidate cancer drug for use against Chagas disease.
Kraus JM, Verlinde CL, Karimi M, Lepesheva GI, Gelb MH, Buckner FS
(2009) J Med Chem 52: 1639-47
MeSH Terms: Alkyl and Aryl Transferases, Animals, Antineoplastic Agents, Chagas Disease, Humans, Mice, Mice, Inbred BALB C, Models, Molecular, Quinolones, Rats, Trypanocidal Agents
Added July 2, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Primary coenzyme Q deficiency in Pdss2 mutant mice causes isolated renal disease.
Peng M, Falk MJ, Haase VH, King R, Polyak E, Selak M, Yudkoff M, Hancock WW, Meade R, Saiki R, Lunceford AL, Clarke CF, Gasser DL
(2008) PLoS Genet 4: e1000061
MeSH Terms: Alkyl and Aryl Transferases, Animals, Base Sequence, DNA Primers, Electron Transport, Gene Expression Profiling, Kidney, Kidney Diseases, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, Mutant Strains, Mitochondria, Liver, Mitochondrial Diseases, Mutation, Missense, Oligonucleotide Array Sequence Analysis, Phenotype, Ubiquinone
Added August 19, 2013
0 Communities
1 Members
0 Resources
18 MeSH Terms