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Glucose-mediated inhibition of calcium-activated potassium channels limits α-cell calcium influx and glucagon secretion.
Dickerson MT, Dadi PK, Altman MK, Verlage KR, Thorson AS, Jordan KL, Vierra NC, Amarnath G, Jacobson DA
(2019) Am J Physiol Endocrinol Metab 316: E646-E659
MeSH Terms: Alkanes, Animals, Apamin, Calcium, Calcium Channels, Calcium Channels, L-Type, Calcium Channels, P-Type, Calcium Channels, Q-Type, Endoplasmic Reticulum, Glucagon, Glucagon-Secreting Cells, Glucose, Mice, Mice, Transgenic, Patch-Clamp Techniques, Peptides, Potassium Channel Blockers, Potassium Channels, Calcium-Activated, Pyrazoles, Quinolinium Compounds
Added February 13, 2019
0 Communities
1 Members
0 Resources
20 MeSH Terms
Dictyostelium cells migrate similarly on surfaces of varying chemical composition.
McCann CP, Rericha EC, Wang C, Losert W, Parent CA
(2014) PLoS One 9: e87981
MeSH Terms: Alkanes, Cell Adhesion, Cell Membrane, Cell Movement, Cell Polarity, Dictyostelium, Glass, Myosin Type II, Polylysine, Serum Albumin, Bovine, Silanes, Surface Properties, Talin
Added April 29, 2016
1 Communities
0 Members
0 Resources
13 MeSH Terms
Association between plasma PFOA and PFOS levels and total cholesterol in a middle-aged Danish population.
Eriksen KT, Raaschou-Nielsen O, McLaughlin JK, Lipworth L, Tjønneland A, Overvad K, Sørensen M
(2013) PLoS One 8: e56969
MeSH Terms: Aged, Alkanesulfonic Acids, Caprylates, Cholesterol, Cross-Sectional Studies, Denmark, Environmental Exposure, Female, Fluorocarbons, Humans, Male, Middle Aged, Population Surveillance
Added March 1, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Amended safety assessment of dodecylbenzenesulfonate, decylbenzenesulfonate, and tridecylbenzenesulfonate salts as used in cosmetics.
Becker LC, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG, Shank RC, Slaga TJ, Snyder PW, Andersen FA
(2010) Int J Toxicol 29: 288S-305
MeSH Terms: Alkanesulfonic Acids, Animals, Benzenesulfonates, Chemical Phenomena, Consumer Product Safety, Cosmetics, Detergents, Dose-Response Relationship, Drug, Humans, Irritants, Mutagenicity Tests, Rabbits, Skin, Surface-Active Agents, Toxicity Tests, Acute, Toxicity Tests, Chronic
Added March 20, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Prenatal exposure to PFOA and PFOS and risk of hospitalization for infectious diseases in early childhood.
Fei C, McLaughlin JK, Lipworth L, Olsen J
(2010) Environ Res 110: 773-7
MeSH Terms: Adult, Alkanesulfonic Acids, Caprylates, Child, Child, Preschool, Communicable Diseases, Denmark, Environmental Monitoring, Environmental Pollutants, Epidemiological Monitoring, Female, Fluorocarbons, Hospitalization, Humans, Infant, Male, Maternal Exposure, Pregnancy, Prenatal Exposure Delayed Effects
Added March 1, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms
The tubulin-bound conformation of discodermolide derived by NMR studies in solution supports a common pharmacophore model for epothilone and discodermolide.
Sánchez-Pedregal VM, Kubicek K, Meiler J, Lyothier I, Paterson I, Carlomagno T
(2006) Angew Chem Int Ed Engl 45: 7388-94
MeSH Terms: Alkanes, Carbamates, Epothilones, Lactones, Magnetic Resonance Spectroscopy, Models, Molecular, Molecular Conformation, Protein Binding, Pyrones, Solutions, Tubulin
Added January 24, 2015
1 Communities
1 Members
0 Resources
11 MeSH Terms
Analysis of the kinetic mechanism of haloalkane conjugation by mammalian theta-class glutathione transferases.
Guengerich FP, McCormick WA, Wheeler JB
(2003) Chem Res Toxicol 16: 1493-9
MeSH Terms: Alkanes, Animals, Ethylene Dichlorides, Glutathione, Glutathione Transferase, Humans, Hydrocarbons, Brominated, Hydrocarbons, Halogenated, Kinetics, Methane, Methylene Chloride, Models, Chemical, Rats
Added March 5, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Conjugation of haloalkanes by bacterial and mammalian glutathione transferases: mono- and vicinal dihaloethanes.
Wheeler JB, Stourman NV, Armstrong RN, Guengerich FP
(2001) Chem Res Toxicol 14: 1107-17
MeSH Terms: Alkanes, Animals, Bacteria, Catalysis, Ethane, Glutathione Transferase, Hydrocarbons, Halogenated, Hydrolysis, Kinetics, Mammals, Mustard Compounds, Mutagenicity Tests, Salmonella typhimurium
Added March 5, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Annexins V and XII insert into bilayers at mildly acidic pH and form ion channels.
Isas JM, Cartailler JP, Sokolov Y, Patel DR, Langen R, Luecke H, Hall JE, Haigler HT
(2000) Biochemistry 39: 3015-22
MeSH Terms: Alkanesulfonic Acids, Animals, Annexin A5, Annexins, Azirines, Buffers, Humans, Hydra, Hydrogen-Ion Concentration, Iodine Radioisotopes, Ion Channels, Lipid Bilayers, Morpholines, Octoxynol, Phospholipids, Photoaffinity Labels, Polyethylene Glycols, Sodium Acetate, Spin Labels, Tromethamine
Added March 26, 2013
1 Communities
1 Members
0 Resources
20 MeSH Terms
Dihaloalkanes and polyhaloalkenes.
Guengerich FP, Min KS, Persmark M, Kim MS, Humphreys WG, Cmarik JM, Thier R
(1994) IARC Sci Publ : 57-72
MeSH Terms: Alkanes, Alkenes, Animals, Carcinogens, DNA, DNA Adducts, Humans, Hydrocarbons, Halogenated, Neoplasms, Experimental
Added March 5, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms