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Horse Liver Alcohol Dehydrogenase: Zinc Coordination and Catalysis.
Plapp BV, Savarimuthu BR, Ferraro DJ, Rubach JK, Brown EN, Ramaswamy S
(2017) Biochemistry 56: 3632-3646
MeSH Terms: 2,2'-Dipyridyl, Adenosine Diphosphate Ribose, Alcohol Dehydrogenase, Animals, Catalytic Domain, Crystallography, X-Ray, Formamides, Horses, Kinetics, Liver, Models, Molecular, NAD, Phenanthrolines, Protein Binding, Protein Conformation, Water, Zinc
Added August 31, 2017
0 Communities
1 Members
0 Resources
17 MeSH Terms
Isotope-Labeling Studies Support the Electrophilic Compound I Iron Active Species, FeO(3+), for the Carbon-Carbon Bond Cleavage Reaction of the Cholesterol Side-Chain Cleavage Enzyme, Cytochrome P450 11A1.
Yoshimoto FK, Jung IJ, Goyal S, Gonzalez E, Guengerich FP
(2016) J Am Chem Soc 138: 12124-41
MeSH Terms: Alcohol Dehydrogenase, Caproates, Carbon, Cholesterol, Cholesterol Side-Chain Cleavage Enzyme, Ferric Compounds, Isotope Labeling, Oxygen, Yeasts
Added March 14, 2018
0 Communities
1 Members
0 Resources
9 MeSH Terms
Clostridium difficile infection.
Smits WK, Lyras D, Lacy DB, Wilcox MH, Kuijper EJ
(2016) Nat Rev Dis Primers 2: 16020
MeSH Terms: Ampicillin, Anti-Bacterial Agents, Bacterial Toxins, Clindamycin, Clostridioides difficile, Clostridium Infections, Diarrhea, Enterotoxins, Gastrointestinal Microbiome, Humans, Risk Factors, Sugar Alcohol Dehydrogenases
Added April 26, 2017
0 Communities
1 Members
0 Resources
12 MeSH Terms
A novel short-chain alcohol dehydrogenase from rats with retinol dehydrogenase activity, cyclically expressed in uterine epithelium.
Rexer BN, Ong DE
(2002) Biol Reprod 67: 1555-64
MeSH Terms: Adenocarcinoma, Alcohol Dehydrogenase, Alcohol Oxidoreductases, Aldehyde Dehydrogenase, Amino Acid Sequence, Animals, Base Sequence, Breast Neoplasms, Cells, Cultured, Cloning, Molecular, Cytochrome P450 Family 2, Epithelium, Estrous Cycle, Female, Molecular Sequence Data, RNA, Messenger, Rats, Rats, Sprague-Dawley, Receptors, Retinoic Acid, Reverse Transcriptase Polymerase Chain Reaction, Transfection, Tretinoin, Uterus, Vitamin A
Added March 10, 2014
0 Communities
1 Members
0 Resources
24 MeSH Terms
ADR1-mediated transcriptional activation requires the presence of an intact TFIID complex.
Komarnitsky PB, Klebanow ER, Weil PA, Denis CL
(1998) Mol Cell Biol 18: 5861-7
MeSH Terms: Alcohol Dehydrogenase, Bacterial Proteins, Binding Sites, Cell Cycle Proteins, DNA-Binding Proteins, Fungal Proteins, Gene Expression Regulation, Fungal, Precipitin Tests, Recombinant Fusion Proteins, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, Serine Endopeptidases, TATA-Binding Protein Associated Factors, TATA-Box Binding Protein, Transcription Factor TFIID, Transcription Factors, Transcription Factors, TFII, Transcriptional Activation
Added March 5, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
Formation of 1,N2- and N2,3-ethenoguanine from 2-halooxiranes: isotopic labeling studies and isolation of a hemiaminal derivative of N2-(2-oxoethyl)guanine.
Guengerich FP, Persmark M, Humphreys WG
(1993) Chem Res Toxicol 6: 635-48
MeSH Terms: Alcohol Dehydrogenase, Animals, Chromatography, High Pressure Liquid, Epoxide Hydrolases, Epoxy Compounds, Guanine, Imidazoles, In Vitro Techniques, Isotope Labeling, Kinetics, Magnetic Resonance Spectroscopy, Microsomes, Mutagens, Purines, Rats, Spectrophotometry, Ultraviolet
Added March 5, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
The identification and formation of 20-aldehyde leukotriene B4.
Soberman RJ, Sutyak JP, Okita RT, Wendelborn DF, Roberts LJ, Austen KF
(1988) J Biol Chem 263: 7996-8002
MeSH Terms: Alcohol Dehydrogenase, Animals, Chromatography, High Pressure Liquid, Cytochrome P-450 Enzyme System, Horses, Humans, Isoenzymes, Leukocytes, Mononuclear, Leukotriene B4, Mass Spectrometry, Microsomes, NADP
Added December 10, 2013
0 Communities
1 Members
0 Resources
12 MeSH Terms
Purification and structural characterization of placental NAD(+)-linked 15-hydroxyprostaglandin dehydrogenase. The primary structure reveals the enzyme to belong to the short-chain alcohol dehydrogenase family.
Krook M, Marekov L, Jörnvall H
(1990) Biochemistry 29: 738-43
MeSH Terms: Alcohol Dehydrogenase, Amino Acid Sequence, Anion Exchange Resins, Chromatography, Female, Humans, Hydroxyprostaglandin Dehydrogenases, Placenta, Pregnancy, Resins, Synthetic, Sepharose
Added September 9, 2013
0 Communities
0 Members
1 Resources
11 MeSH Terms
Catalytic activities of human liver cytochrome P-450 IIIA4 expressed in Saccharomyces cerevisiae.
Brian WR, Sari MA, Iwasaki M, Shimada T, Kaminsky LS, Guengerich FP
(1990) Biochemistry 29: 11280-92
MeSH Terms: Alcohol Dehydrogenase, Aryl Hydrocarbon Hydroxylases, Cloning, Molecular, Cytochrome P-450 CYP2C8, Cytochrome P-450 CYP2C9, Cytochrome P-450 Enzyme System, Cytochrome P450 Family 2, Gene Expression, Genetic Vectors, Humans, Kinetics, Liver, Microsomes, Microsomes, Liver, Plasmids, Promoter Regions, Genetic, Recombinant Fusion Proteins, Saccharomyces cerevisiae, Spectrophotometry, Steroid 16-alpha-Hydroxylase, Substrate Specificity
Added March 5, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms
NADP-dependent 15-hydroxyprostaglandin dehydrogenase is homologous to NAD-dependent 15-hydroxyprostaglandin dehydrogenase and other short-chain alcohol dehydrogenases.
Wermuth B
(1992) Prostaglandins 44: 5-9
MeSH Terms: Alcohol Dehydrogenase, Amino Acid Sequence, Humans, Hydroxyprostaglandin Dehydrogenases, Molecular Sequence Data, NADP, Sequence Homology, Nucleic Acid, Substrate Specificity
Added September 9, 2013
0 Communities
0 Members
1 Resources
8 MeSH Terms