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Temporal manipulation of KCC3 expression in juvenile or adult mice suggests irreversible developmental deficit in hereditary motor sensory neuropathy with agenesis of the corpus callosum.
Flores B, Delpire E
(2021) Am J Physiol Cell Physiol 320: C722-C730
MeSH Terms: Age Factors, Agenesis of Corpus Callosum, Animals, Behavior, Animal, Disease Models, Animal, Female, Ganglia, Spinal, Gene Expression Regulation, Developmental, Genetic Predisposition to Disease, Genetic Therapy, Male, Mice, Inbred C57BL, Mice, Knockout, Motor Activity, Parvalbumins, Peripheral Nervous System Diseases, Phenotype, Postural Balance, Rotarod Performance Test, Symporters
Added February 26, 2021
1 Communities
0 Members
0 Resources
20 MeSH Terms
GABA interneurons are the cellular trigger for ketamine's rapid antidepressant actions.
Gerhard DM, Pothula S, Liu RJ, Wu M, Li XY, Girgenti MJ, Taylor SR, Duman CH, Delpire E, Picciotto M, Wohleb ES, Duman RS
(2020) J Clin Invest 130: 1336-1349
MeSH Terms: Animals, Antidepressive Agents, Female, GABAergic Neurons, Gene Knockout Techniques, Glutamate Decarboxylase, Interneurons, Ketamine, Male, Mice, Mice, Transgenic, Parvalbumins, Receptors, N-Methyl-D-Aspartate, Sex Characteristics, Somatostatin
Added March 18, 2020
0 Communities
1 Members
0 Resources
15 MeSH Terms
iPSC-Derived Brain Endothelium Exhibits Stable, Long-Term Barrier Function in Perfused Hydrogel Scaffolds.
Faley SL, Neal EH, Wang JX, Bosworth AM, Weber CM, Balotin KM, Lippmann ES, Bellan LM
(2019) Stem Cell Reports 12: 474-487
MeSH Terms: Albumins, Blood-Brain Barrier, Brain, Cells, Cultured, Dextrans, Endothelial Cells, Endothelium, Fluorescein, Humans, Hydrogels, Induced Pluripotent Stem Cells, Microvessels
Added March 18, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Imaging mass spectrometry reveals direct albumin fragmentation within the diabetic kidney.
Grove KJ, Lareau NM, Voziyan PA, Zeng F, Harris RC, Hudson BG, Caprioli RM
(2018) Kidney Int 94: 292-302
MeSH Terms: Albumins, Albuminuria, Animals, Cathepsin D, Diabetic Nephropathies, Disease Models, Animal, Frozen Sections, Humans, Kidney Glomerulus, Kidney Tubules, Mice, Mice, Inbred C57BL, Molecular Imaging, Nitric Oxide Synthase Type III, Proteolysis, Renal Elimination, Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Added May 29, 2018
1 Communities
1 Members
0 Resources
17 MeSH Terms
Early Detection of Treatment-Induced Mitotic Arrest Using Temporal Diffusion Magnetic Resonance Spectroscopy.
Jiang X, Li H, Zhao P, Xie J, Khabele D, Xu J, Gore JC
(2016) Neoplasia 18: 387-97
MeSH Terms: Albumins, Animals, Antineoplastic Agents, Phytogenic, Apoptosis, Biomarkers, Tumor, Cell Line, Tumor, Cell Size, Female, Flow Cytometry, Humans, Magnetic Resonance Spectroscopy, Mice, Mice, Nude, Mitosis, Mitotic Index, Paclitaxel, Xenograft Model Antitumor Assays
Added November 1, 2016
0 Communities
2 Members
0 Resources
17 MeSH Terms
A phase 1b study of erlotinib in combination with gemcitabine and nab-paclitaxel in patients with previously untreated advanced pancreatic cancer: an Academic Oncology GI Cancer Consortium study.
Cohen SJ, O'Neil BH, Berlin J, Ames P, McKinley M, Horan J, Catalano PM, Davies A, Weekes CD, Leichman L
(2016) Cancer Chemother Pharmacol 77: 693-701
MeSH Terms: Aged, Albumins, Antineoplastic Combined Chemotherapy Protocols, Deoxycytidine, Erlotinib Hydrochloride, Female, Humans, Male, Middle Aged, Paclitaxel, Pancreatic Neoplasms
Added May 7, 2016
0 Communities
1 Members
0 Resources
11 MeSH Terms
Activation of Metabotropic Glutamate Receptor 7 Is Required for Induction of Long-Term Potentiation at SC-CA1 Synapses in the Hippocampus.
Klar R, Walker AG, Ghose D, Grueter BA, Engers DW, Hopkins CR, Lindsley CW, Xiang Z, Conn PJ, Niswender CM
(2015) J Neurosci 35: 7600-15
MeSH Terms: Animals, CA1 Region, Hippocampal, CA3 Region, Hippocampal, Channelrhodopsins, Electric Stimulation, Excitatory Amino Acid Agonists, Excitatory Amino Acid Antagonists, Hippocampus, In Vitro Techniques, Inhibitory Postsynaptic Potentials, Interneurons, Long-Term Potentiation, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, Models, Biological, Parvalbumins, Patch-Clamp Techniques, Receptors, Metabotropic Glutamate
Added February 18, 2016
0 Communities
2 Members
0 Resources
20 MeSH Terms
Contrast-Enhanced Subharmonic and Harmonic Ultrasound of Renal Masses Undergoing Percutaneous Cryoablation.
Eisenbrey JR, Shaw CM, Lyshchik A, Machado P, Lallas CD, Trabulsi EJ, Merton DA, Fox TB, Liu JB, Brown DB, Forsberg F
(2015) Acad Radiol 22: 820-6
MeSH Terms: Aged, Aged, 80 and over, Albumins, Carcinoma, Renal Cell, Contrast Media, Cryosurgery, Female, Fluorocarbons, Hepatectomy, Humans, Image Enhancement, Kidney Neoplasms, Male, Middle Aged, Prognosis, Reproducibility of Results, Sensitivity and Specificity, Surgery, Computer-Assisted, Treatment Outcome, Ultrasonography
Added September 18, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
Inhibition of parvalbumin-expressing interneurons results in complex behavioral changes.
Brown JA, Ramikie TS, Schmidt MJ, Báldi R, Garbett K, Everheart MG, Warren LE, Gellért L, Horváth S, Patel S, Mirnics K
(2015) Mol Psychiatry 20: 1499-507
MeSH Terms: Animals, Behavior, Animal, Brain, Disease Models, Animal, Electrophysiology, Exploratory Behavior, Fear, Gene Silencing, Glutamate Decarboxylase, Interneurons, Ketamine, Male, Mice, Mice, Inbred C3H, Mice, Transgenic, Parvalbumins, Receptors, N-Methyl-D-Aspartate, Schizophrenia, Sensory Gating, Synaptic Transmission
Added February 12, 2015
0 Communities
2 Members
0 Resources
20 MeSH Terms
Loss of dopamine D2 receptors increases parvalbumin-positive interneurons in the anterior cingulate cortex.
Graham DL, Durai HH, Garden JD, Cohen EL, Echevarria FD, Stanwood GD
(2015) ACS Chem Neurosci 6: 297-305
MeSH Terms: Animals, Cell Count, Depression, Emotions, Female, GABAergic Neurons, Glutamate Decarboxylase, Green Fluorescent Proteins, Gyrus Cinguli, Immunohistochemistry, In Situ Hybridization, Fluorescence, Interneurons, Male, Mice, Inbred C57BL, Mice, Knockout, Mice, Transgenic, Neuropsychological Tests, Parvalbumins, Receptors, Dopamine D2
Added January 20, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms