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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 10

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Bacterial-derived Neutrophilic Inflammation Drives Lung Remodeling in a Mouse Model of Chronic Obstructive Pulmonary Disease.
Richmond BW, Du RH, Han W, Benjamin JT, van der Meer R, Gleaves L, Guo M, McKissack A, Zhang Y, Cheng DS, Polosukhin VV, Blackwell TS
(2018) Am J Respir Cell Mol Biol 58: 736-744
MeSH Terms: Airway Remodeling, Aminopyridines, Animals, Bacillus, Benzamides, Cyclopropanes, Disease Models, Animal, Mice, Inbred C57BL, Mice, Mutant Strains, Neutrophils, Pneumonia, Bacterial, Pulmonary Disease, Chronic Obstructive, Pulmonary Emphysema, Receptors, Cell Surface
Added March 21, 2018
0 Communities
3 Members
0 Resources
14 MeSH Terms
Secretory IgA Deficiency in Individual Small Airways Is Associated with Persistent Inflammation and Remodeling.
Polosukhin VV, Richmond BW, Du RH, Cates JM, Wu P, Nian H, Massion PP, Ware LB, Lee JW, Kononov AV, Lawson WE, Blackwell TS
(2017) Am J Respir Crit Care Med 195: 1010-1021
MeSH Terms: Aged, Airway Remodeling, Chronic Disease, Female, Humans, IgA Deficiency, Inflammation, Lung, Male, Middle Aged
Added March 29, 2017
1 Communities
4 Members
0 Resources
10 MeSH Terms
Airway bacteria drive a progressive COPD-like phenotype in mice with polymeric immunoglobulin receptor deficiency.
Richmond BW, Brucker RM, Han W, Du RH, Zhang Y, Cheng DS, Gleaves L, Abdolrasulnia R, Polosukhina D, Clark PE, Bordenstein SR, Blackwell TS, Polosukhin VV
(2016) Nat Commun 7: 11240
MeSH Terms: Aging, Airway Remodeling, Aminopyridines, Animals, Benzamides, Cyclic Nucleotide Phosphodiesterases, Type 4, Cyclopropanes, Disease Models, Animal, Gene Expression Regulation, Host-Pathogen Interactions, Humans, Immunity, Innate, Immunoglobulin A, Secretory, Leukocyte Elastase, Lung, Matrix Metalloproteinase 12, Mice, Mice, Inbred C57BL, Mice, Knockout, Microbiota, NF-kappa B, Phosphodiesterase 4 Inhibitors, Pulmonary Disease, Chronic Obstructive, Pulmonary Emphysema, Receptors, Polymeric Immunoglobulin, Respiratory Mucosa
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Intratracheal bleomycin causes airway remodeling and airflow obstruction in mice.
Polosukhin VV, Degryse AL, Newcomb DC, Jones BR, Ware LB, Lee JW, Loyd JE, Blackwell TS, Lawson WE
(2012) Exp Lung Res 38: 135-46
MeSH Terms: Airway Obstruction, Airway Remodeling, Animals, Antibiotics, Antineoplastic, Bleomycin, Disease Models, Animal, Epithelial Cells, Female, Fibroblasts, Humans, Idiopathic Pulmonary Fibrosis, Inflammation, Lung, Male, Mice, Mice, Inbred C57BL, S100 Calcium-Binding Protein A4, S100 Proteins, Transforming Growth Factor beta1, Transforming Growth Factor beta2
Added March 5, 2014
1 Communities
3 Members
0 Resources
20 MeSH Terms
Telomerase deficiency does not alter bleomycin-induced fibrosis in mice.
Degryse AL, Xu XC, Newman JL, Mitchell DB, Tanjore H, Polosukhin VV, Jones BR, McMahon FB, Gleaves LA, Phillips JA, Cogan JD, Blackwell TS, Lawson WE
(2012) Exp Lung Res 38: 124-34
MeSH Terms: Airway Remodeling, Animals, Antibiotics, Antineoplastic, Bleomycin, Collagen, Epithelial Cells, Female, Idiopathic Pulmonary Fibrosis, Leukocytes, Lung, Male, Mice, Mice, Inbred C57BL, Mutation, Pneumonia, Pulmonary Alveoli, RNA, Telomerase, Telomere Homeostasis, Telomere Shortening
Added March 5, 2014
1 Communities
2 Members
0 Resources
20 MeSH Terms
Hypoxia-inducible factor-1 signalling promotes goblet cell hyperplasia in airway epithelium.
Polosukhin VV, Cates JM, Lawson WE, Milstone AP, Matafonov AG, Massion PP, Lee JW, Randell SH, Blackwell TS
(2011) J Pathol 224: 203-11
MeSH Terms: Adolescent, Adult, Aged, Aged, 80 and over, Airway Remodeling, Bronchi, Cell Differentiation, Cell Hypoxia, Cells, Cultured, Enzyme Activation, Female, Goblet Cells, Humans, Hyperplasia, Hypoxia-Inducible Factor 1, Male, Middle Aged, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, Mucin 5AC, Pulmonary Disease, Chronic Obstructive, Respiratory Mucosa, Signal Transduction, Young Adult
Added March 15, 2013
1 Communities
4 Members
0 Resources
24 MeSH Terms
Bronchial secretory immunoglobulin a deficiency correlates with airway inflammation and progression of chronic obstructive pulmonary disease.
Polosukhin VV, Cates JM, Lawson WE, Zaynagetdinov R, Milstone AP, Massion PP, Ocak S, Ware LB, Lee JW, Bowler RP, Kononov AV, Randell SH, Blackwell TS
(2011) Am J Respir Crit Care Med 184: 317-27
MeSH Terms: Airway Remodeling, Bronchi, Cytomegalovirus, Herpesvirus 4, Human, Humans, Immunoglobulin A, Secretory, Inflammation, Pulmonary Disease, Chronic Obstructive, Receptors, Polymeric Immunoglobulin, Respiratory System, Smoking, Time
Added March 15, 2013
1 Communities
4 Members
0 Resources
12 MeSH Terms
Somatic mutations in pulmonary arterial hypertension: primary or secondary events?
Austin ED, Hamid R, Ahmad F
(2010) Am J Respir Crit Care Med 182: 1094-6
MeSH Terms: Airway Remodeling, Bone Morphogenetic Protein Receptors, Type II, Germ-Line Mutation, Humans, Hypertension, Pulmonary, Pulmonary Artery, Smad8 Protein
Added March 27, 2014
0 Communities
2 Members
0 Resources
7 MeSH Terms
Somatic chromosome abnormalities in the lungs of patients with pulmonary arterial hypertension.
Aldred MA, Comhair SA, Varella-Garcia M, Asosingh K, Xu W, Noon GP, Thistlethwaite PA, Tuder RM, Erzurum SC, Geraci MW, Coldren CD
(2010) Am J Respir Crit Care Med 182: 1153-60
MeSH Terms: Adult, Airway Remodeling, Bone Morphogenetic Protein Receptors, Type II, Cell Proliferation, Child, Chromosome Aberrations, Chromosome Deletion, DNA Copy Number Variations, Endothelial Cells, Female, Gene Rearrangement, Genome-Wide Association Study, Genomic Instability, Germ-Line Mutation, Humans, Hypertension, Pulmonary, In Situ Hybridization, Fluorescence, Lung, Microarray Analysis, Middle Aged, Myocytes, Smooth Muscle, Polymorphism, Single Nucleotide, Pulmonary Artery, Pulmonary Disease, Chronic Obstructive, X Chromosome Inactivation
Added November 17, 2011
0 Communities
1 Members
0 Resources
25 MeSH Terms
A matrix metalloproteinase mediates airway remodeling in Drosophila.
Glasheen BM, Robbins RM, Piette C, Beitel GJ, Page-McCaw A
(2010) Dev Biol 344: 772-83
MeSH Terms: Airway Remodeling, Animals, Drosophila, Embryo, Nonmammalian, Extracellular Matrix, Larva, Matrix Metalloproteinases, Respiratory System, Trachea
Added March 5, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms