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Smashing the strict hierarchy: three cases of clinical decision support malfunctions involving carvedilol.
Wright A, Wright AP, Aaron S, Sittig DF
(2018) J Am Med Inform Assoc 25: 1552-1555
MeSH Terms: Adrenergic alpha-1 Receptor Antagonists, Adrenergic beta-Antagonists, Carvedilol, Decision Support Systems, Clinical, Electronic Health Records, Humans, Knowledge Management, Medication Errors, Terminology as Topic, Vocabulary, Controlled
Added November 7, 2019
0 Communities
1 Members
0 Resources
10 MeSH Terms
Beta-blockers and Traumatic Brain Injury: A Systematic Review, Meta-analysis, and Eastern Association for the Surgery of Trauma Guideline.
Alali AS, Mukherjee K, McCredie VA, Golan E, Shah PS, Bardes JM, Hamblin SE, Haut ER, Jackson JC, Khwaja K, Patel NJ, Raj SR, Wilson LD, Nathens AB, Patel MB
(2017) Ann Surg 266: 952-961
MeSH Terms: Adrenergic beta-Antagonists, Brain Injuries, Bronchial Spasm, Cardiovascular Diseases, Hospital Mortality, Humans, Quality of Life, Treatment Outcome
Added June 26, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Efficacy of Flecainide in the Treatment of Catecholaminergic Polymorphic Ventricular Tachycardia: A Randomized Clinical Trial.
Kannankeril PJ, Moore JP, Cerrone M, Priori SG, Kertesz NJ, Ro PS, Batra AS, Kaufman ES, Fairbrother DL, Saarel EV, Etheridge SP, Kanter RJ, Carboni MP, Dzurik MV, Fountain D, Chen H, Ely EW, Roden DM, Knollmann BC
(2017) JAMA Cardiol 2: 759-766
MeSH Terms: Adolescent, Adrenergic beta-Antagonists, Anti-Arrhythmia Agents, Cross-Over Studies, Death, Sudden, Cardiac, Defibrillators, Implantable, Drug Therapy, Combination, Exercise, Exercise Test, Female, Flecainide, Humans, Male, Maximum Tolerated Dose, Single-Blind Method, Tachycardia, Ventricular, Young Adult
Added March 24, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Genome-wide association study identifies pharmacogenomic loci linked with specific antihypertensive drug treatment and new-onset diabetes.
Chang SW, McDonough CW, Gong Y, Johnson TA, Tsunoda T, Gamazon ER, Perera MA, Takahashi A, Tanaka T, Kubo M, Pepine CJ, Johnson JA, Cooper-DeHoff RM
(2018) Pharmacogenomics J 18: 106-112
MeSH Terms: Adrenergic beta-Antagonists, African Americans, Aged, Alleles, Antihypertensive Agents, Calcium Channel Blockers, Diabetes Mellitus, Female, Follow-Up Studies, Genome-Wide Association Study, Humans, Hypertension, Male, Meta-Analysis as Topic, Middle Aged, Odds Ratio, Pharmacogenetics, Polymorphism, Single Nucleotide, Quantitative Trait Loci
Added April 13, 2017
0 Communities
1 Members
0 Resources
19 MeSH Terms
Analysis for Genetic Modifiers of Disease Severity in Patients With Long-QT Syndrome Type 2.
Kolder ICRM, Tanck MWT, Postema PG, Barc J, Sinner MF, Zumhagen S, Husemann A, Stallmeyer B, Koopmann TT, Hofman N, Pfeufer A, Lichtner P, Meitinger T, Beckmann BM, Myerburg RJ, Bishopric NH, Roden DM, Kääb S, Wilde AAM, Schott JJ, Schulze-Bahr E, Bezzina CR
(2015) Circ Cardiovasc Genet 8: 447-456
MeSH Terms: Adaptor Proteins, Signal Transducing, Adrenergic beta-Antagonists, Alleles, Case-Control Studies, Electrocardiography, Female, Genome-Wide Association Study, Genotype, Humans, KCNQ1 Potassium Channel, Long QT Syndrome, Male, Odds Ratio, Polymorphism, Single Nucleotide, Risk Factors, Severity of Illness Index
Added March 24, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Novel calmodulin mutations associated with congenital arrhythmia susceptibility.
Makita N, Yagihara N, Crotti L, Johnson CN, Beckmann BM, Roh MS, Shigemizu D, Lichtner P, Ishikawa T, Aiba T, Homfray T, Behr ER, Klug D, Denjoy I, Mastantuono E, Theisen D, Tsunoda T, Satake W, Toda T, Nakagawa H, Tsuji Y, Tsuchiya T, Yamamoto H, Miyamoto Y, Endo N, Kimura A, Ozaki K, Motomura H, Suda K, Tanaka T, Schwartz PJ, Meitinger T, Kääb S, Guicheney P, Shimizu W, Bhuiyan ZA, Watanabe H, Chazin WJ, George AL
(2014) Circ Cardiovasc Genet 7: 466-74
MeSH Terms: Adrenergic beta-Antagonists, Adult, Age of Onset, Amino Acid Sequence, Calcium, Calmodulin, Child, Child, Preschool, Electrocardiography, Female, Genetic Predisposition to Disease, High-Throughput Nucleotide Sequencing, Humans, Infant, Long QT Syndrome, Male, Molecular Sequence Data, Mutation, Missense, Pedigree, Protein Binding, Sequence Analysis, DNA, Tachycardia, Ventricular
Added January 20, 2015
0 Communities
1 Members
0 Resources
22 MeSH Terms
Applied pharmacogenomics in cardiovascular medicine.
Weeke P, Roden DM
(2014) Annu Rev Med 65: 81-94
MeSH Terms: Adrenergic beta-Antagonists, Antihypertensive Agents, Antithrombins, Aryl Hydrocarbon Hydroxylases, Cardiovascular Diseases, Clopidogrel, Cytochrome P-450 CYP2C19, Cytochrome P-450 CYP2C9, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Liver-Specific Organic Anion Transporter 1, Organic Anion Transporters, Pharmacogenetics, Polymorphism, Single Nucleotide, Precision Medicine, Ticlopidine, Vitamin K Epoxide Reductases, Warfarin
Added March 7, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
QT variability during initial exposure to sotalol: experience based on a large electronic medical record.
Weeke P, Delaney J, Mosley JD, Wells Q, Van Driest S, Norris K, Kucera G, Stubblefield T, Roden DM
(2013) Europace 15: 1791-7
MeSH Terms: Adrenergic beta-Antagonists, Aged, Anti-Arrhythmia Agents, Electronic Health Records, Female, Heart Conduction System, Humans, Linear Models, Logistic Models, Long QT Syndrome, Male, Middle Aged, Multivariate Analysis, Odds Ratio, Risk Assessment, Risk Factors, Sotalol, Time Factors, Torsades de Pointes
Added February 28, 2014
0 Communities
3 Members
0 Resources
19 MeSH Terms
Locus coeruleus kappa-opioid receptors modulate reinstatement of cocaine place preference through a noradrenergic mechanism.
Al-Hasani R, McCall JG, Foshage AM, Bruchas MR
(2013) Neuropsychopharmacology 38: 2484-97
MeSH Terms: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer, Adrenergic alpha-2 Receptor Agonists, Adrenergic beta-1 Receptor Antagonists, Adrenergic beta-Antagonists, Animals, Betaxolol, Clonidine, Cocaine, Conditioning, Psychological, Drug-Seeking Behavior, Locus Coeruleus, Male, Mice, Mice, Inbred C57BL, Naltrexone, Propanolamines, Propranolol, Receptors, Adrenergic, alpha, Receptors, Adrenergic, beta, Receptors, Opioid, kappa
Added May 15, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
Pharmacogenomics and cardiovascular disease.
Weeke P, Roden DM
(2013) Curr Cardiol Rep 15: 376
MeSH Terms: Adrenergic beta-Antagonists, Cardiovascular Agents, Cardiovascular Diseases, Clopidogrel, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Polymorphism, Genetic, Practice Guidelines as Topic, Ticlopidine, Warfarin
Added March 7, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms