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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 7 of 7

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Second messenger signaling mechanisms of the brown adipocyte thermogenic program: an integrative perspective.
Shi F, Collins S
(2017) Horm Mol Biol Clin Investig 31:
MeSH Terms: Adipocytes, Beige, Adipocytes, Brown, Animals, Cyclic AMP-Dependent Protein Kinases, Cyclic GMP-Dependent Protein Kinases, Energy Metabolism, Gene Expression Regulation, Humans, Intracellular Space, Mechanistic Target of Rapamycin Complex 1, MicroRNAs, Natriuretic Agents, RNA, Long Noncoding, Receptors, Adrenergic, beta, Second Messenger Systems, Signal Transduction, Thermogenesis, Uncoupling Protein 1
Added September 26, 2018
0 Communities
2 Members
0 Resources
MeSH Terms
β-Aminoisobutyric acid induces browning of white fat and hepatic β-oxidation and is inversely correlated with cardiometabolic risk factors.
Roberts LD, Boström P, O'Sullivan JF, Schinzel RT, Lewis GD, Dejam A, Lee YK, Palma MJ, Calhoun S, Georgiadi A, Chen MH, Ramachandran VS, Larson MG, Bouchard C, Rankinen T, Souza AL, Clish CB, Wang TJ, Estall JL, Soukas AA, Cowan CA, Spiegelman BM, Gerszten RE
(2014) Cell Metab 19: 96-108
MeSH Terms: Adipocytes, Brown, Adipocytes, White, Adipose Tissue, Brown, Adipose Tissue, White, Aminoisobutyric Acids, Animals, Cardiovascular Diseases, Cell Differentiation, Exercise, Gene Expression Regulation, Glucose Tolerance Test, Humans, Induced Pluripotent Stem Cells, Liver, Metabolic Diseases, Mice, Organ Specificity, Oxidation-Reduction, PPAR alpha, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Phenotype, Physical Conditioning, Animal, Risk Factors, Transcription Factors, Transcription, Genetic, Weight Gain
Added February 28, 2014
1 Communities
1 Members
0 Resources
26 MeSH Terms
p62 links β-adrenergic input to mitochondrial function and thermogenesis.
Müller TD, Lee SJ, Jastroch M, Kabra D, Stemmer K, Aichler M, Abplanalp B, Ananthakrishnan G, Bhardwaj N, Collins S, Divanovic S, Endele M, Finan B, Gao Y, Habegger KM, Hembree J, Heppner KM, Hofmann S, Holland J, Küchler D, Kutschke M, Krishna R, Lehti M, Oelkrug R, Ottaway N, Perez-Tilve D, Raver C, Walch AK, Schriever SC, Speakman J, Tseng YH, Diaz-Meco M, Pfluger PT, Moscat J, Tschöp MH
(2013) J Clin Invest 123: 469-78
MeSH Terms: Adaptor Proteins, Signal Transducing, Adipocytes, Brown, Adipose Tissue, Brown, Animals, Cells, Cultured, Heat-Shock Proteins, MAP Kinase Signaling System, Mice, Mice, Knockout, Mitochondria, Mitochondrial Proteins, Organ Specificity, Sequestosome-1 Protein, Thermogenesis, Transcription Factors, p38 Mitogen-Activated Protein Kinases
Added July 22, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
The chemical chaperones tauroursodeoxycholic and 4-phenylbutyric acid accelerate thyroid hormone activation and energy expenditure.
da-Silva WS, Ribich S, Arrojo e Drigo R, Castillo M, Patti ME, Bianco AC
(2011) FEBS Lett 585: 539-44
MeSH Terms: Adipocytes, Brown, Animals, Cell Line, Cells, Cultured, Dietary Fats, Energy Metabolism, Gene Expression Regulation, Gene Knockout Techniques, Glucose Intolerance, Humans, Iodide Peroxidase, Lipid Metabolism, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Oxygen Consumption, Phenylbutyrates, RNA, Messenger, Taurochenodeoxycholic Acid, Triiodothyronine
Added April 14, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
De novo generation of white adipocytes from the myeloid lineage via mesenchymal intermediates is age, adipose depot, and gender specific.
Majka SM, Fox KE, Psilas JC, Helm KM, Childs CR, Acosta AS, Janssen RC, Friedman JE, Woessner BT, Shade TR, Varella-Garcia M, Klemm DJ
(2010) Proc Natl Acad Sci U S A 107: 14781-6
MeSH Terms: Adipocytes, Brown, Adipocytes, White, Adipose Tissue, Age Factors, Animals, Bone Marrow Cells, Cell Differentiation, Cell Lineage, Cells, Cultured, Cytogenetic Analysis, Female, Gene Expression Profiling, Male, Mesoderm, Mice, Models, Biological, Myeloid Cells, Oligonucleotide Array Sequence Analysis, Sex Factors
Added August 4, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms
ADD1/SREBP1c activates the PGC1-alpha promoter in brown adipocytes.
Hao Q, Hansen JB, Petersen RK, Hallenborg P, Jørgensen C, Cinti S, Larsen PJ, Steffensen KR, Wang H, Collins S, Wang J, Gustafsson JA, Madsen L, Kristiansen K
(2010) Biochim Biophys Acta 1801: 421-9
MeSH Terms: Adipocytes, Brown, Animals, Cell Differentiation, Cells, Cultured, Chromatin Immunoprecipitation, Electrophoretic Mobility Shift Assay, Electroporation, Liver X Receptors, Male, Mice, Mice, Inbred C57BL, Orphan Nuclear Receptors, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha, Promoter Regions, Genetic, RNA, Messenger, Regulatory Sequences, Nucleic Acid, Reverse Transcriptase Polymerase Chain Reaction, Sterol Regulatory Element Binding Protein 1, Trans-Activators, Transcription Factors
Added July 22, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Liver X receptor alpha is a transcriptional repressor of the uncoupling protein 1 gene and the brown fat phenotype.
Wang H, Zhang Y, Yehuda-Shnaidman E, Medvedev AV, Kumar N, Daniel KW, Robidoux J, Czech MP, Mangelsdorf DJ, Collins S
(2008) Mol Cell Biol 28: 2187-200
MeSH Terms: Adaptor Proteins, Signal Transducing, Adipocytes, Brown, Adrenergic beta-Agonists, Animals, Body Temperature, Cell Differentiation, Cells, Cultured, Colforsin, DNA-Binding Proteins, Enhancer Elements, Genetic, Ion Channels, Liver X Receptors, Mice, Mice, Inbred C57BL, Mice, Knockout, Mitochondria, Mitochondrial Proteins, Nuclear Proteins, Nuclear Receptor Interacting Protein 1, Orphan Nuclear Receptors, Oxygen Consumption, PPAR gamma, RNA, Small Interfering, Receptors, Cytoplasmic and Nuclear, Signal Transduction, Transcription, Genetic, Uncoupling Protein 1
Added July 22, 2020
0 Communities
1 Members
0 Resources
MeSH Terms