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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 33

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α- and α-Adrenoceptors as Potential Targets for Dopamine and Dopamine Receptor Ligands.
Sánchez-Soto M, Casadó-Anguera V, Yano H, Bender BJ, Cai NS, Moreno E, Canela EI, Cortés A, Meiler J, Casadó V, Ferré S
(2018) Mol Neurobiol 55: 8438-8454
MeSH Terms: Adenylyl Cyclases, Animals, Cerebral Cortex, Clonidine, Dopamine, Extracellular Signal-Regulated MAP Kinases, GTP-Binding Proteins, HEK293 Cells, Humans, Idazoxan, Ligands, Neostriatum, Norepinephrine, Phosphorylation, Quinpirole, Receptors, Adrenergic, alpha-2, Receptors, Dopamine, Sheep, Tetrahydronaphthalenes
Added March 21, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Regulator of G-protein signaling 6 (RGS6) promotes anxiety and depression by attenuating serotonin-mediated activation of the 5-HT(1A) receptor-adenylyl cyclase axis.
Stewart A, Maity B, Wunsch AM, Meng F, Wu Q, Wemmie JA, Fisher RA
(2014) FASEB J 28: 1735-44
MeSH Terms: 8-Hydroxy-2-(di-n-propylamino)tetralin, Adenylyl Cyclases, Animals, Animals, Newborn, Anxiety, Cells, Cultured, Cerebral Cortex, Depression, Female, Fluvoxamine, Hippocampus, Immunoblotting, Immunohistochemistry, Male, Mice, Phosphorylation, Piperazines, Proto-Oncogene Proteins c-akt, Pyridines, RGS Proteins, Receptor, Serotonin, 5-HT1A, Serotonin, Serotonin Antagonists, Serotonin Receptor Agonists, Serotonin Uptake Inhibitors, Signal Transduction
Added August 7, 2014
0 Communities
1 Members
0 Resources
26 MeSH Terms
Absence of Ca2+-stimulated adenylyl cyclases leads to reduced synaptic plasticity and impaired experience-dependent fear memory.
Wieczorek L, Majumdar D, Wills TA, Hu L, Winder DG, Webb DJ, Muglia LJ
(2012) Transl Psychiatry 2: e126
MeSH Terms: Adenylyl Cyclases, Animals, Calcium, Crosses, Genetic, Fear, Gene-Environment Interaction, Hippocampus, Long-Term Potentiation, Membrane Glycoproteins, Mental Recall, Mice, Mice, Inbred C57BL, Mice, Knockout, Nerve Tissue Proteins, Neurogenesis, Neuronal Plasticity, Prosencephalon, Synapses
Added May 19, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
Functional selectivity induced by mGlu₄ receptor positive allosteric modulation and concomitant activation of Gq coupled receptors.
Yin S, Zamorano R, Conn PJ, Niswender CM
(2013) Neuropharmacology 66: 122-32
MeSH Terms: Adenylyl Cyclase Inhibitors, Adenylyl Cyclases, Allosteric Regulation, Animals, Benzopyrans, Calcium, Calcium Signaling, Cell Line, Excitatory Amino Acid Agonists, Excitatory Amino Acid Antagonists, GTP-Binding Protein alpha Subunits, Gq-G11, Glutamic Acid, Guinea Pigs, Histamine, Humans, Phosphatidylinositols, Rats, Receptors, Histamine H1, Receptors, Metabotropic Glutamate, Signal Transduction
Added February 19, 2015
0 Communities
2 Members
0 Resources
20 MeSH Terms
GSK3beta mediates renal response to vasopressin by modulating adenylate cyclase activity.
Rao R, Patel S, Hao C, Woodgett J, Harris R
(2010) J Am Soc Nephrol 21: 428-37
MeSH Terms: Adenylyl Cyclases, Animals, Antidiuretic Agents, Aquaporin 2, Cells, Cultured, Colforsin, Cyclic AMP, Deamino Arginine Vasopressin, Female, Glycogen Synthase Kinase 3, Glycogen Synthase Kinase 3 beta, Kidney Concentrating Ability, Kidney Tubules, Collecting, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, RNA, Messenger, Water Deprivation, Water-Electrolyte Balance
Added August 19, 2013
1 Communities
1 Members
0 Resources
20 MeSH Terms
RACK1 regulates specific functions of Gbetagamma.
Chen S, Dell EJ, Lin F, Sai J, Hamm HE
(2004) J Biol Chem 279: 17861-8
MeSH Terms: Adenylyl Cyclases, Animals, COS Cells, Cell Line, Cell Membrane, Chemotaxis, Cyclic AMP, Cytosol, Dimerization, Dose-Response Relationship, Drug, Enzyme Activation, GTP-Binding Protein beta Subunits, GTP-Binding Protein gamma Subunits, GTP-Binding Proteins, Gene Expression Regulation, Glutathione Transferase, Humans, Hydrolysis, Interleukin-8, Isoenzymes, Lipid Metabolism, MAP Kinase Signaling System, Microscopy, Confocal, Microscopy, Fluorescence, Neoplasm Proteins, Phospholipase C beta, Protein Binding, Protein Transport, Receptors for Activated C Kinase, Receptors, Cell Surface, Signal Transduction, Transfection, Type C Phospholipases
Added January 20, 2015
0 Communities
1 Members
0 Resources
33 MeSH Terms
Androgen receptor activity at the prostate specific antigen locus: steroidal and non-steroidal mechanisms.
Jia L, Kim J, Shen H, Clark PE, Tilley WD, Coetzee GA
(2003) Mol Cancer Res 1: 385-92
MeSH Terms: Acetylation, Adenylyl Cyclases, Cell Division, Colforsin, Dihydrotestosterone, Genes, Reporter, Histones, Humans, Interleukin-6, Ligands, Luciferases, Male, Promoter Regions, Genetic, Prostate-Specific Antigen, Prostatic Neoplasms, Receptors, Androgen, Tumor Cells, Cultured
Added May 27, 2014
0 Communities
1 Members
0 Resources
17 MeSH Terms
Prostaglandin receptor EP2 mediates PGE2 stimulated hypercalcemia in mice in vivo.
Li X, Tomita M, Pilbeam CC, Breyer RM, Raisz LG
(2002) Prostaglandins Other Lipid Mediat 67: 173-80
MeSH Terms: Actins, Adenylyl Cyclases, Animals, Blotting, Northern, Bone and Bones, Calcium, Carrier Proteins, Cyclic AMP, Dinoprostone, Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating), Glycoproteins, Hypercalcemia, Male, Membrane Glycoproteins, Mice, Mice, Inbred C57BL, Mice, Knockout, Osteoblasts, Osteoclasts, Osteogenesis, Osteoprotegerin, RANK Ligand, RNA, Messenger, Receptor Activator of Nuclear Factor-kappa B, Receptors, Cytoplasmic and Nuclear, Receptors, Prostaglandin E, Receptors, Prostaglandin E, EP2 Subtype, Receptors, Tumor Necrosis Factor
Added December 21, 2013
0 Communities
1 Members
0 Resources
28 MeSH Terms
Mapping the lethal factor and edema factor binding sites on oligomeric anthrax protective antigen.
Cunningham K, Lacy DB, Mogridge J, Collier RJ
(2002) Proc Natl Acad Sci U S A 99: 7049-53
MeSH Terms: Adenylyl Cyclases, Animals, Antigens, Bacterial, Bacillus anthracis, Bacterial Toxins, Binding Sites, CHO Cells, Chromosome Mapping, Cricetinae, Dimerization, Ligands, Models, Molecular, Mutagenesis, Protein Structure, Tertiary
Added May 7, 2013
0 Communities
1 Members
0 Resources
14 MeSH Terms
The lethal and edema factors of anthrax toxin bind only to oligomeric forms of the protective antigen.
Mogridge J, Cunningham K, Lacy DB, Mourez M, Collier RJ
(2002) Proc Natl Acad Sci U S A 99: 7045-8
MeSH Terms: Adenylyl Cyclases, Antigens, Bacterial, Bacillus anthracis, Bacterial Toxins, Ligands, Mutagenesis, Oligopeptides, Solutions
Added May 7, 2013
0 Communities
1 Members
0 Resources
8 MeSH Terms