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Rab25 regulates integrin expression in polarized colonic epithelial cells.
Krishnan M, Lapierre LA, Knowles BC, Goldenring JR
(2013) Mol Biol Cell 24: 818-31
MeSH Terms: Adenovirus E1A Proteins, Caco-2 Cells, Cell Line, Tumor, Cell Movement, Cell Polarity, Claudin-1, Epithelial Cells, Gene Expression Regulation, Gene Expression Regulation, Neoplastic, HEK293 Cells, Humans, Integrin alpha2, Integrin alpha5, Integrin alpha5beta1, Integrin beta1, Integrins, Intestinal Mucosa, Microvilli, Neoplasm Invasiveness, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-ets, RNA Interference, rab GTP-Binding Proteins
Added October 7, 2013
1 Communities
2 Members
0 Resources
23 MeSH Terms
Adenoviral E1A function through Myc.
Chakraborty AA, Tansey WP
(2009) Cancer Res 69: 6-9
MeSH Terms: Adenoviridae, Adenovirus E1A Proteins, Animals, Cell Transformation, Viral, DNA Tumor Viruses, Humans, Proto-Oncogene Proteins c-myc
Added March 10, 2014
0 Communities
1 Members
0 Resources
7 MeSH Terms
Adenovirus E1A targets p400 to induce the cellular oncoprotein Myc.
Tworkowski KA, Chakraborty AA, Samuelson AV, Seger YR, Narita M, Hannon GJ, Lowe SW, Tansey WP
(2008) Proc Natl Acad Sci U S A 105: 6103-8
MeSH Terms: Adenovirus E1A Proteins, Cell Line, Cell Transformation, Viral, Chromatin Immunoprecipitation, DNA Helicases, DNA-Binding Proteins, Humans, Proto-Oncogene Proteins c-myc
Added March 10, 2014
0 Communities
1 Members
0 Resources
8 MeSH Terms
Transcriptional regulation of the cyclooxygenase-2 gene in macrophages by PU.1.
Joo M, Park GY, Wright JG, Blackwell TS, Atchison ML, Christman JW
(2004) J Biol Chem 279: 6658-65
MeSH Terms: Adenovirus E1A Proteins, Animals, Base Sequence, Binding Sites, Blotting, Western, CCAAT-Enhancer-Binding Protein-beta, Cell Line, Chromatin, Cyclooxygenase 2, Cytoplasm, Gene Expression Regulation, Enzymologic, Genetic Vectors, Isoenzymes, Lipopolysaccharides, Macrophages, Mice, Models, Biological, Molecular Sequence Data, Plasmids, Precipitin Tests, Prostaglandin-Endoperoxide Synthases, Protein Binding, Protein Structure, Tertiary, Proto-Oncogene Proteins, Serine, Time Factors, Trans-Activators, Transcription, Genetic, Transfection
Added March 5, 2014
1 Communities
1 Members
0 Resources
29 MeSH Terms
Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2, and E47.
Qiu Y, Guo M, Huang S, Stein R
(2002) Mol Cell Biol 22: 412-20
MeSH Terms: Adenovirus E1A Proteins, Animals, Basic Helix-Loop-Helix Transcription Factors, Cell Line, DNA-Binding Proteins, E1A-Associated p300 Protein, Enhancer Elements, Genetic, Gene Expression Regulation, HeLa Cells, Homeodomain Proteins, Humans, Insulin, Islets of Langerhans, Macromolecular Substances, Mastadenovirus, Nuclear Proteins, Rats, TCF Transcription Factors, Trans-Activators, Transcription Factor 7-Like 1 Protein, Transcription Factors, Transcription, Genetic, Transfection
Added December 10, 2013
0 Communities
1 Members
0 Resources
23 MeSH Terms
Cationic liposome-mediated E1A gene transfer to human breast and ovarian cancer cells and its biologic effects: a phase I clinical trial.
Hortobagyi GN, Ueno NT, Xia W, Zhang S, Wolf JK, Putnam JB, Weiden PL, Willey JS, Carey M, Branham DL, Payne JY, Tucker SD, Bartholomeusz C, Kilbourn RG, De Jager RL, Sneige N, Katz RL, Anklesaria P, Ibrahim NK, Murray JL, Theriault RL, Valero V, Gershenson DM, Bevers MW, Huang L, Lopez-Berestein G, Hung MC
(2001) J Clin Oncol 19: 3422-33
MeSH Terms: Adenovirus E1A Proteins, Adult, Aged, Apoptosis, Breast Neoplasms, Cholesterol, Cytokines, Female, Gene Expression, Gene Transfer, Horizontal, Genes, erbB-2, Genetic Therapy, Humans, Immunohistochemistry, In Situ Nick-End Labeling, Injections, Ki-67 Antigen, Liposomes, Middle Aged, Ovarian Neoplasms, Peritoneal Cavity, Reverse Transcriptase Polymerase Chain Reaction, Thorax, Tumor Cells, Cultured
Added March 27, 2014
0 Communities
1 Members
0 Resources
24 MeSH Terms
Oncogenes induce and activate endogenous p73 protein.
Zaika A, Irwin M, Sansome C, Moll UM
(2001) J Biol Chem 276: 11310-6
MeSH Terms: Adenovirus E1A Proteins, Carrier Proteins, Cell Cycle Proteins, DNA-Binding Proteins, E2F Transcription Factors, E2F1 Transcription Factor, Gene Expression Regulation, Neoplastic, Genes, Tumor Suppressor, Genes, myc, Humans, Nuclear Proteins, Oncogenes, Retinoblastoma-Binding Protein 1, Transcription Factor DP1, Transcription Factors, Tumor Cells, Cultured, Tumor Protein p73, Tumor Suppressor Proteins
Added March 5, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
Requirement of an E1A-sensitive coactivator for long-range transactivation by the beta-globin locus control region.
Forsberg EC, Johnson K, Zaboikina TN, Mosser EA, Bresnick EH
(1999) J Biol Chem 274: 26850-9
MeSH Terms: Acetyltransferases, Adenovirus E1A Proteins, Animals, DNA-Binding Proteins, E1A-Associated p300 Protein, Erythroid-Specific DNA-Binding Factors, Globins, Histone Acetyltransferases, Humans, Leukemia, Erythroblastic, Acute, Locus Control Region, Mice, NF-E2 Transcription Factor, NF-E2 Transcription Factor, p45 Subunit, Nuclear Proteins, Polymerase Chain Reaction, Saccharomyces cerevisiae Proteins, Trans-Activators, Transcription Factors, Transcriptional Activation, Tumor Cells, Cultured
Added June 15, 2010
0 Communities
1 Members
0 Resources
21 MeSH Terms
Adenovirus E1A expression enhances the sensitivity of an ovarian cancer cell line to multiple cytotoxic agents through an apoptotic mechanism.
Brader KR, Wolf JK, Hung MC, Yu D, Crispens MA, van Golen KL, Price JE
(1997) Clin Cancer Res 3: 2017-24
MeSH Terms: Adenovirus E1A Proteins, Animals, Antineoplastic Agents, Apoptosis, Cell Division, Cell Survival, Cisplatin, DNA Fragmentation, Doxorubicin, Female, Flow Cytometry, Humans, Mice, Mice, Nude, Ovarian Neoplasms, Paclitaxel, Recombinant Proteins, Transfection, Transplantation, Heterologous, Tumor Cells, Cultured, Tumor Necrosis Factor-alpha
Added March 5, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms
Regions of the retinoblastoma gene product required for its interaction with the E2F transcription factor are necessary for E2 promoter repression and pRb-mediated growth suppression.
Hiebert SW
(1993) Mol Cell Biol 13: 3384-91
MeSH Terms: Adenovirus E1A Proteins, Adenovirus E2 Proteins, Binding Sites, Carrier Proteins, Cell Cycle, Cell Cycle Proteins, Cell Division, DNA-Binding Proteins, E2F Transcription Factors, Female, G1 Phase, Genes, Retinoblastoma, Humans, Promoter Regions, Genetic, Retinoblastoma Protein, Retinoblastoma-Binding Protein 1, Transcription Factor DP1, Transcription Factors, Transfection, Tumor Cells, Cultured, Uterine Cervical Neoplasms
Added June 10, 2010
1 Communities
1 Members
0 Resources
21 MeSH Terms