Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 10 of 22

Publication Record

Connections

Combining Chimeric Mice with Humanized Liver, Mass Spectrometry, and Physiologically-Based Pharmacokinetic Modeling in Toxicology.
Yamazaki H, Suemizu H, Mitsui M, Shimizu M, Guengerich FP
(2016) Chem Res Toxicol 29: 1903-1911
MeSH Terms: Activation, Metabolic, Animals, Chimera, Cytochrome P-450 Enzyme System, Humans, Liver, Mass Spectrometry, Mice, Thalidomide, Toxicokinetics
Added March 14, 2018
0 Communities
1 Members
0 Resources
10 MeSH Terms
Exercise and the Regulation of Hepatic Metabolism.
Trefts E, Williams AS, Wasserman DH
(2015) Prog Mol Biol Transl Sci 135: 203-25
MeSH Terms: Animals, Carbon, Exercise, Humans, Inactivation, Metabolic, Liver, Metabolome, Motor Activity
Added May 5, 2016
1 Communities
1 Members
0 Resources
8 MeSH Terms
Streptomyces cytochromes P450: applications in drug metabolism.
Lamb DC, Waterman MR, Zhao B
(2013) Expert Opin Drug Metab Toxicol 9: 1279-94
MeSH Terms: Biotransformation, Cytochrome P-450 Enzyme System, Drug Evaluation, Preclinical, Drug-Related Side Effects and Adverse Reactions, Genomics, Humans, Inactivation, Metabolic, Streptomyces, Xenobiotics
Added March 7, 2014
0 Communities
1 Members
0 Resources
9 MeSH Terms
New trends in cytochrome p450 research at the half-century mark.
Guengerich FP
(2013) J Biol Chem 288: 17063-4
MeSH Terms: Animals, Biomedical Research, Cytochrome P-450 Enzyme System, Humans, Inactivation, Metabolic, Molecular Biology, Oxidation-Reduction, Steroids
Added March 7, 2014
0 Communities
1 Members
0 Resources
8 MeSH Terms
Antimicrobial dosing in acute renal replacement.
Fissell WH
(2013) Adv Chronic Kidney Dis 20: 85-93
MeSH Terms: Acute Kidney Injury, Anti-Bacterial Agents, Antifungal Agents, Biological Availability, Critical Care, Critical Illness, Drug Administration Schedule, Drug Dosage Calculations, Humans, Inactivation, Metabolic, Metabolic Clearance Rate, Piperacillin, Practice Guidelines as Topic, Renal Replacement Therapy, Tissue Distribution
Added August 21, 2013
0 Communities
1 Members
0 Resources
15 MeSH Terms
Contributions of human enzymes in carcinogen metabolism.
Rendic S, Guengerich FP
(2012) Chem Res Toxicol 25: 1316-83
MeSH Terms: Carcinogens, Chemoprevention, Cytochrome P-450 Enzyme System, Enzymes, Humans, Inactivation, Metabolic, Risk Assessment
Added March 26, 2014
0 Communities
1 Members
0 Resources
7 MeSH Terms
The limits of genome-wide methods for pharmacogenomic testing.
Gamazon ER, Skol AD, Perera MA
(2012) Pharmacogenet Genomics 22: 261-72
MeSH Terms: Biomarkers, Pharmacological, Databases, Genetic, European Continental Ancestry Group, Genetic Association Studies, Genetic Variation, Genome, Human, Genotype, HapMap Project, Humans, Inactivation, Metabolic, Linkage Disequilibrium, Pharmacogenetics, Polymorphism, Single Nucleotide
Added April 13, 2017
0 Communities
1 Members
0 Resources
13 MeSH Terms
Overexpression of Cu/Zn-superoxide dismutase and/or catalase accelerates benzo(a)pyrene detoxification by upregulation of the aryl hydrocarbon receptor in mouse endothelial cells.
Wang Z, Yang H, Ramesh A, Roberts LJ, Zhou L, Lin X, Zhao Y, Guo Z
(2009) Free Radic Biol Med 47: 1221-9
MeSH Terms: Animals, Aorta, Aryl Hydrocarbon Hydroxylases, Benzo(a)pyrene, Blotting, Western, Catalase, Cells, Cultured, Cytochrome P-450 CYP1A1, Cytochrome P-450 CYP1B1, Endothelium, Vascular, F2-Isoprostanes, Furans, Glutathione Transferase, Inactivation, Metabolic, Mice, RNA, Messenger, RNA, Small Interfering, Receptors, Aryl Hydrocarbon, Reverse Transcriptase Polymerase Chain Reaction, Superoxide Dismutase, Up-Regulation
Added February 22, 2016
0 Communities
1 Members
0 Resources
21 MeSH Terms
Breast cancer resistance protein (ABCG2) and drug disposition: intestinal expression, polymorphisms and sulfasalazine as an in vivo probe.
Urquhart BL, Ware JA, Tirona RG, Ho RH, Leake BF, Schwarz UI, Zaher H, Palandra J, Gregor JC, Dresser GK, Kim RB
(2008) Pharmacogenet Genomics 18: 439-48
MeSH Terms: ATP Binding Cassette Transporter, Subfamily G, Member 2, ATP-Binding Cassette Transporters, Adolescent, Adult, Caco-2 Cells, Drug Resistance, Neoplasm, Female, Gastrointestinal Agents, HeLa Cells, Humans, Inactivation, Metabolic, Intestinal Mucosa, Male, Metabolic Clearance Rate, Middle Aged, Neoplasm Proteins, Polymorphism, Single Nucleotide, Sulfasalazine, Tissue Distribution
Added March 5, 2014
2 Communities
2 Members
0 Resources
19 MeSH Terms
Cytochrome p450 and chemical toxicology.
Guengerich FP
(2008) Chem Res Toxicol 21: 70-83
MeSH Terms: Animals, Animals, Genetically Modified, Biotransformation, Cytochrome P-450 Enzyme System, Drug-Related Side Effects and Adverse Reactions, Gene Library, Humans, Inactivation, Metabolic, Ligands, Metabolism, Polymorphism, Genetic, Toxicology
Added March 5, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms