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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 172

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RYR2 Channel Inhibition Is the Principal Mechanism of Flecainide Action in CPVT.
Kryshtal DO, Blackwell DJ, Egly CL, Smith AN, Batiste SM, Johnston JN, Laver DR, Knollmann BC
(2021) Circ Res 128: 321-331
MeSH Terms: Action Potentials, Animals, Anti-Arrhythmia Agents, Calcium Channel Blockers, Calcium Signaling, Calsequestrin, Disease Models, Animal, Female, Flecainide, HEK293 Cells, Heart Rate, Humans, Male, Mice, Knockout, Myocytes, Cardiac, Phosphorylation, Ryanodine Receptor Calcium Release Channel, Sarcoplasmic Reticulum, Sheep, Domestic, Tachycardia, Ventricular, Voltage-Gated Sodium Channel Blockers
Added December 21, 2020
1 Communities
0 Members
0 Resources
21 MeSH Terms
Ibrutinib-Mediated Atrial Fibrillation Attributable to Inhibition of C-Terminal Src Kinase.
Xiao L, Salem JE, Clauss S, Hanley A, Bapat A, Hulsmans M, Iwamoto Y, Wojtkiewicz G, Cetinbas M, Schloss MJ, Tedeschi J, Lebrun-Vignes B, Lundby A, Sadreyev RI, Moslehi J, Nahrendorf M, Ellinor PT, Milan DJ
(2020) Circulation 142: 2443-2455
MeSH Terms: Action Potentials, Adenine, Agammaglobulinaemia Tyrosine Kinase, Animals, Antineoplastic Agents, Atrial Fibrillation, Atrial Function, Left, CSK Tyrosine-Protein Kinase, Databases, Genetic, Heart Atria, Heart Rate, Humans, Mice, 129 Strain, Mice, Inbred C57BL, Mice, Inbred CBA, Mice, Knockout, Piperidines, Protein Kinase Inhibitors, Risk Assessment, Risk Factors
Added January 23, 2021
0 Communities
1 Members
0 Resources
20 MeSH Terms
Sign Inversion in Photopharmacology: Incorporation of Cyclic Azobenzenes in Photoswitchable Potassium Channel Blockers and Openers.
Trads JB, Hüll K, Matsuura BS, Laprell L, Fehrentz T, Görldt N, Kozek KA, Weaver CD, Klöcker N, Barber DM, Trauner D
(2019) Angew Chem Int Ed Engl 58: 15421-15428
MeSH Terms: Action Potentials, Azo Compounds, Cyclization, Drug Design, G Protein-Coupled Inwardly-Rectifying Potassium Channels, HEK293 Cells, Humans, Isomerism, Lidocaine, Light, Patch-Clamp Techniques, Potassium Channel Blockers, Thermodynamics
Added March 27, 2020
0 Communities
1 Members
0 Resources
13 MeSH Terms
On the Relationship between MRI and Local Field Potential Measurements of Spatial and Temporal Variations in Functional Connectivity.
Shi Z, Wilkes DM, Yang PF, Wang F, Wu R, Wu TL, Chen LM, Gore JC
(2019) Sci Rep 9: 8871
MeSH Terms: Action Potentials, Animals, Brain Mapping, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Saimiri, Somatosensory Cortex, Spatio-Temporal Analysis
Added July 11, 2019
0 Communities
2 Members
0 Resources
8 MeSH Terms
SCN5A variant R222Q generated abnormal changes in cardiac sodium current and action potentials in murine myocytes and Purkinje cells.
Daniel LL, Yang T, Kroncke B, Hall L, Stroud D, Roden DM
(2019) Heart Rhythm 16: 1676-1685
MeSH Terms: Action Potentials, Alleles, Animals, Disease Models, Animal, Echocardiography, Electrocardiography, Mice, Mice, Transgenic, Myocytes, Cardiac, NAV1.5 Voltage-Gated Sodium Channel, Purkinje Cells, Sodium Channels
Added June 14, 2019
1 Communities
2 Members
0 Resources
12 MeSH Terms
Electrophysiologic and molecular mechanisms of a frameshift NPPA mutation linked with familial atrial fibrillation.
Menon A, Hong L, Savio-Galimberti E, Sridhar A, Youn SW, Zhang M, Kor K, Blair M, Kupershmidt S, Darbar D
(2019) J Mol Cell Cardiol 132: 24-35
MeSH Terms: Action Potentials, Animals, Atrial Fibrillation, Atrial Natriuretic Factor, Electrophysiological Phenomena, Frameshift Mutation, Heart Atria, Humans, Membrane Potentials, Mice, Mice, Transgenic, Myocytes, Cardiac, NAV1.5 Voltage-Gated Sodium Channel
Added June 14, 2019
1 Communities
0 Members
0 Resources
13 MeSH Terms
Patient-independent human induced pluripotent stem cell model: A new tool for rapid determination of genetic variant pathogenicity in long QT syndrome.
Chavali NV, Kryshtal DO, Parikh SS, Wang L, Glazer AM, Blackwell DJ, Kroncke BM, Shoemaker MB, Knollmann BC
(2019) Heart Rhythm 16: 1686-1695
MeSH Terms: Action Potentials, Calcium Channels, L-Type, Child, Clustered Regularly Interspaced Short Palindromic Repeats, Female, Gene Editing, Genetic Testing, Genetic Variation, Humans, Induced Pluripotent Stem Cells, Long QT Syndrome, Pedigree, Phenotype
Added March 4, 2020
0 Communities
1 Members
0 Resources
13 MeSH Terms
Intrinsic functional architecture of the non-human primate spinal cord derived from fMRI and electrophysiology.
Wu TL, Yang PF, Wang F, Shi Z, Mishra A, Wu R, Chen LM, Gore JC
(2019) Nat Commun 10: 1416
MeSH Terms: Action Potentials, Animals, Electrophysiological Phenomena, Haplorhini, Humans, Magnetic Resonance Imaging, Physical Stimulation, Reproducibility of Results, Rest, Spinal Cord, Spinal Cord Dorsal Horn, Touch
Added July 11, 2019
0 Communities
2 Members
0 Resources
MeSH Terms
The expanding roles and mechanisms of G protein-mediated presynaptic inhibition.
Zurawski Z, Yim YY, Alford S, Hamm HE
(2019) J Biol Chem 294: 1661-1670
MeSH Terms: Action Potentials, Biochemistry, History, 20th Century, History, 21st Century, Humans, Periodicals as Topic, Presynaptic Terminals, Receptors, G-Protein-Coupled, Synaptic Transmission
Added March 24, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
A current understanding of drug-induced QT prolongation and its implications for anticancer therapy.
Roden DM
(2019) Cardiovasc Res 115: 895-903
MeSH Terms: Action Potentials, Animals, Antineoplastic Agents, Genetic Predisposition to Disease, Heart Conduction System, Heart Rate, Humans, Long QT Syndrome, Membrane Transport Proteins, Molecular Targeted Therapy, Prognosis, Risk Assessment, Risk Factors
Added March 24, 2020
0 Communities
1 Members
0 Resources
13 MeSH Terms