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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 14

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Cortactin: a multifunctional regulator of cellular invasiveness.
Kirkbride KC, Sung BH, Sinha S, Weaver AM
(2011) Cell Adh Migr 5: 187-98
MeSH Terms: Actin Cytoskeleton, Actin-Related Protein 2, Actin-Related Protein 3, Actins, Animals, Binding Sites, Biomarkers, Tumor, Cell Communication, Cell Movement, Cortactin, Cytoskeleton, Female, Gene Expression, Humans, Mice, Neoplasms, Polymerization, Protein Binding, Protein Structure, Tertiary, Signal Transduction, Wiskott-Aldrich Syndrome Protein Family
Added March 5, 2014
1 Communities
1 Members
0 Resources
21 MeSH Terms
Cortactin promotes cell motility by enhancing lamellipodial persistence.
Bryce NS, Clark ES, Leysath JL, Currie JD, Webb DJ, Weaver AM
(2005) Curr Biol 15: 1276-85
MeSH Terms: Actin-Related Protein 2, Actin-Related Protein 3, Actins, Adenosine Diphosphate, Adenosine Triphosphate, Base Sequence, Blotting, Western, Cell Line, Cell Movement, Cortactin, Cytoskeletal Proteins, Humans, Kymography, Microfilament Proteins, Microscopy, Fluorescence, Protein Binding, Pseudopodia
Added March 5, 2014
0 Communities
2 Members
0 Resources
17 MeSH Terms
Podosome formation in cultured A7r5 vascular smooth muscle cells requires Arp2/3-dependent de-novo actin polymerization at discrete microdomains.
Kaverina I, Stradal TE, Gimona M
(2003) J Cell Sci 116: 4915-24
MeSH Terms: Actin Cytoskeleton, Actin-Related Protein 2, Actin-Related Protein 3, Actinin, Actins, Animals, Cell Membrane, Cells, Cultured, Cloning, Molecular, Cytoskeletal Proteins, Focal Adhesions, Glycoproteins, Microfilament Proteins, Microscopy, Confocal, Microscopy, Fluorescence, Muscle Proteins, Myocytes, Smooth Muscle, Rats, Stress Fibers, Vinculin, Zyxin
Added December 10, 2013
0 Communities
1 Members
0 Resources
21 MeSH Terms
Fgd1, the Cdc42 GEF responsible for Faciogenital Dysplasia, directly interacts with cortactin and mAbp1 to modulate cell shape.
Hou P, Estrada L, Kinley AW, Parsons JT, Vojtek AB, Gorski JL
(2003) Hum Mol Genet 12: 1981-93
MeSH Terms: Actin Cytoskeleton, Actin-Related Protein 2, Actin-Related Protein 3, Amino Acid Sequence, Animals, Cell Line, Cell Size, Cortactin, Cytoskeletal Proteins, Facial Bones, Fibrous Dysplasia, Polyostotic, Guanine Nucleotide Exchange Factors, Mice, Microfilament Proteins, Molecular Sequence Data, Proteins, Sequence Homology, Amino Acid, Syndrome, Urogenital Abnormalities, cdc42 GTP-Binding Protein, src Homology Domains
Added February 27, 2013
0 Communities
1 Members
0 Resources
21 MeSH Terms
Cortactin interacts with WIP in regulating Arp2/3 activation and membrane protrusion.
Kinley AW, Weed SA, Weaver AM, Karginov AV, Bissonette E, Cooper JA, Parsons JT
(2003) Curr Biol 13: 384-93
MeSH Terms: Actin-Related Protein 2, Actin-Related Protein 3, Actins, Animals, CHO Cells, Carrier Proteins, Cell Membrane, Cortactin, Cricetinae, Cytoskeletal Proteins, Humans, Intracellular Signaling Peptides and Proteins, Microfilament Proteins, Protein Structure, Tertiary
Added March 5, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Integration of signals to the Arp2/3 complex.
Weaver AM, Young ME, Lee WL, Cooper JA
(2003) Curr Opin Cell Biol 15: 23-30
MeSH Terms: Actin Cytoskeleton, Actin-Related Protein 2, Actin-Related Protein 3, Animals, Cortactin, Cytoskeletal Proteins, Eukaryotic Cells, Humans, Microfilament Proteins, Proteins, Signal Transduction, Wiskott-Aldrich Syndrome Protein
Added March 5, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Interaction of cortactin and N-WASp with Arp2/3 complex.
Weaver AM, Heuser JE, Karginov AV, Lee WL, Parsons JT, Cooper JA
(2002) Curr Biol 12: 1270-8
MeSH Terms: Actin-Related Protein 2, Actin-Related Protein 3, Actins, Amino Acid Sequence, Animals, Binding Sites, Brain, Cattle, Chickens, Cortactin, Cytoskeletal Proteins, Kinetics, Microfilament Proteins, Molecular Sequence Data, Mutagenesis, Site-Directed, Nerve Tissue Proteins, Protein Conformation, Recombinant Fusion Proteins, Signal Transduction, Thymus Gland, Tryptophan, Wiskott-Aldrich Syndrome, Wiskott-Aldrich Syndrome Protein, Neuronal
Added March 5, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms
Arp2/3 complex: advances on the inner workings of a molecular machine.
Cooper JA, Wear MA, Weaver AM
(2001) Cell 107: 703-5
MeSH Terms: Actin-Related Protein 2, Actin-Related Protein 3, Actins, Animals, Cytoskeletal Proteins, Models, Molecular, Protein Structure, Quaternary, Protein Subunits
Added March 5, 2014
0 Communities
1 Members
0 Resources
8 MeSH Terms
Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation.
Weaver AM, Karginov AV, Kinley AW, Weed SA, Li Y, Parsons JT, Cooper JA
(2001) Curr Biol 11: 370-4
MeSH Terms: Actin Cytoskeleton, Actin-Related Protein 2, Actin-Related Protein 3, Actins, Animals, Binding Sites, Cattle, Cortactin, Cytoskeletal Proteins, Microfilament Proteins, Nerve Tissue Proteins, Recombinant Fusion Proteins, Wiskott-Aldrich Syndrome Protein, Neuronal, src Homology Domains
Added March 5, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex.
Weed SA, Karginov AV, Schafer DA, Weaver AM, Kinley AW, Cooper JA, Parsons JT
(2000) J Cell Biol 151: 29-40
MeSH Terms: Actin-Related Protein 2, Actin-Related Protein 3, Actins, Amino Acid Sequence, Animals, Binding Sites, Biological Transport, Cells, Cultured, Cortactin, Cytoskeletal Proteins, Mice, Microfilament Proteins, Molecular Sequence Data, Protein Binding, Protein Structure, Tertiary, Pseudopodia, Repetitive Sequences, Amino Acid, Sequence Homology, Amino Acid, rac GTP-Binding Proteins
Added March 5, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms