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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 301

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The pore-forming subunit MCU of the mitochondrial Ca uniporter is required for normal glucose-stimulated insulin secretion in vitro and in vivo in mice.
Georgiadou E, Haythorne E, Dickerson MT, Lopez-Noriega L, Pullen TJ, da Silva Xavier G, Davis SPX, Martinez-Sanchez A, Semplici F, Rizzuto R, McGinty JA, French PM, Cane MC, Jacobson DA, Leclerc I, Rutter GA
(2020) Diabetologia 63: 1368-1381
MeSH Terms: Animals, Blotting, Western, Calcium, Electrophoresis, Polyacrylamide Gel, Glucose, Insulin Secretion, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Mitochondria
Added June 14, 2021
0 Communities
1 Members
0 Resources
11 MeSH Terms
The effect of the EP3 antagonist DG-041 on male mice with diet-induced obesity.
Ceddia RP, Downey JD, Morrison RD, Kraemer MP, Davis SE, Wu J, Lindsley CW, Yin H, Daniels JS, Breyer RM
(2019) Prostaglandins Other Lipid Mediat 144: 106353
MeSH Terms: Acrylamides, Animals, Blood Pressure, Body Weight, Diet, High-Fat, HEK293 Cells, Humans, Insulin Resistance, Male, Mice, Muscle, Skeletal, Obesity, Phenotype, Receptors, Prostaglandin E, EP3 Subtype, Sulfones, Triglycerides
Added September 4, 2019
0 Communities
1 Members
0 Resources
16 MeSH Terms
On-target Resistance to the Mutant-Selective EGFR Inhibitor Osimertinib Can Develop in an Allele-Specific Manner Dependent on the Original EGFR-Activating Mutation.
Brown BP, Zhang YK, Westover D, Yan Y, Qiao H, Huang V, Du Z, Smith JA, Ross JS, Miller VA, Ali S, Bazhenova L, Schrock AB, Meiler J, Lovly CM
(2019) Clin Cancer Res 25: 3341-3351
MeSH Terms: Acrylamides, Alleles, Aniline Compounds, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Dose-Response Relationship, Drug, Drug Resistance, Neoplasm, ErbB Receptors, Exons, Gene Expression Profiling, Humans, Lung Neoplasms, Models, Molecular, Mutation, Protein Binding, Protein Kinase Inhibitors, Structure-Activity Relationship
Added March 21, 2020
0 Communities
2 Members
0 Resources
17 MeSH Terms
Proteomic Analysis of S-Palmitoylated Proteins in Ocular Lens Reveals Palmitoylation of AQP5 and MP20.
Wang Z, Schey KL
(2018) Invest Ophthalmol Vis Sci 59: 5648-5658
MeSH Terms: Animals, Aquaporin 5, Blotting, Western, Cattle, Chromatography, Liquid, Electrophoresis, Polyacrylamide Gel, Eye Proteins, Immunoblotting, Lens, Crystalline, Lipoylation, Membrane Proteins, Palmitates, Proteomics, Tandem Mass Spectrometry
Added April 4, 2019
0 Communities
1 Members
0 Resources
14 MeSH Terms
SFK/FAK Signaling Attenuates Osimertinib Efficacy in Both Drug-Sensitive and Drug-Resistant Models of EGFR-Mutant Lung Cancer.
Ichihara E, Westover D, Meador CB, Yan Y, Bauer JA, Lu P, Ye F, Kulick A, de Stanchina E, McEwen R, Ladanyi M, Cross D, Pao W, Lovly CM
(2017) Cancer Res 77: 2990-3000
MeSH Terms: Acrylamides, Aniline Compounds, Animals, Antineoplastic Agents, Drug Resistance, Neoplasm, ErbB Receptors, Female, Focal Adhesion Protein-Tyrosine Kinases, Humans, Lung Neoplasms, Mice, Mice, Nude, Mutation, Piperazines, Signal Transduction, Transfection, src-Family Kinases
Added September 10, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Heterogeneous Mechanisms of Primary and Acquired Resistance to Third-Generation EGFR Inhibitors.
Ortiz-Cuaran S, Scheffler M, Plenker D, Dahmen L, Scheel AH, Fernandez-Cuesta L, Meder L, Lovly CM, Persigehl T, Merkelbach-Bruse S, Bos M, Michels S, Fischer R, Albus K, König K, Schildhaus HU, Fassunke J, Ihle MA, Pasternack H, Heydt C, Becker C, Altmüller J, Ji H, Müller C, Florin A, Heuckmann JM, Nuernberg P, Ansén S, Heukamp LC, Berg J, Pao W, Peifer M, Buettner R, Wolf J, Thomas RK, Sos ML
(2016) Clin Cancer Res 22: 4837-4847
MeSH Terms: Acrylamides, Adenocarcinoma, Adenocarcinoma of Lung, Aged, Aniline Compounds, Antineoplastic Agents, Drug Resistance, Neoplasm, ErbB Receptors, Female, Humans, Lung Neoplasms, Male, Middle Aged, Pyrimidines
Added September 10, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Identification of a Novel Transcript and Regulatory Mechanism for Microsomal Triglyceride Transfer Protein.
Suzuki T, Brown JJ, Swift LL
(2016) PLoS One 11: e0147252
MeSH Terms: Alternative Splicing, Animals, CHO Cells, Carrier Proteins, Cricetulus, Electrophoresis, Polyacrylamide Gel, Female, HEK293 Cells, Humans, Mice, Protein Isoforms, RNA, Messenger, Rabbits, Reverse Transcriptase Polymerase Chain Reaction
Added February 22, 2016
0 Communities
1 Members
0 Resources
14 MeSH Terms
Medically Relevant Acinetobacter Species Require a Type II Secretion System and Specific Membrane-Associated Chaperones for the Export of Multiple Substrates and Full Virulence.
Harding CM, Kinsella RL, Palmer LD, Skaar EP, Feldman MF
(2016) PLoS Pathog 12: e1005391
MeSH Terms: Acinetobacter, Acinetobacter Infections, Animals, Electrophoresis, Gel, Two-Dimensional, Electrophoresis, Polyacrylamide Gel, Humans, Mice, Mice, Inbred C57BL, Molecular Chaperones, Type II Secretion Systems, Virulence
Added February 8, 2016
0 Communities
2 Members
0 Resources
11 MeSH Terms
Microsomal Triglyceride Transfer Protein (MTP) Associates with Cytosolic Lipid Droplets in 3T3-L1 Adipocytes.
Love JD, Suzuki T, Robinson DB, Harris CM, Johnson JE, Mohler PJ, Jerome WG, Swift LL
(2015) PLoS One 10: e0135598
MeSH Terms: 3T3-L1 Cells, Adipocytes, Animals, Carrier Proteins, Cell Differentiation, Cytosol, Electrophoresis, Polyacrylamide Gel, Immunohistochemistry, Lipid Droplets, Mice, Microscopy, Fluorescence, Reverse Transcriptase Polymerase Chain Reaction
Added September 30, 2015
0 Communities
2 Members
0 Resources
12 MeSH Terms
Shades of T790M: Intratumor Heterogeneity in EGFR-Mutant Lung Cancer.
Ichihara E, Lovly CM
(2015) Cancer Discov 5: 694-6
MeSH Terms: Acrylamides, Drug Resistance, Neoplasm, ErbB Receptors, Humans, Lung Neoplasms, Protein Kinase Inhibitors, Pyrimidines, Small Cell Lung Carcinoma
Added January 26, 2016
0 Communities
1 Members
0 Resources
8 MeSH Terms