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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 6 of 6

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Mdmx promotes genomic instability independent of p53 and Mdm2.
Carrillo AM, Bouska A, Arrate MP, Eischen CM
(2015) Oncogene 34: 846-56
MeSH Terms: ATP-Binding Cassette Transporters, Acid Anhydride Hydrolases, Animals, Cell Cycle Proteins, DNA Damage, DNA Repair, DNA Repair Enzymes, DNA-Binding Proteins, Genomic Instability, Humans, MRE11 Homologue Protein, Mice, Mice, Knockout, Neoplasms, Nuclear Proteins, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-mdm2, Signal Transduction, Tumor Suppressor Protein p53
Added March 17, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms
MRE11 deficiency increases sensitivity to poly(ADP-ribose) polymerase inhibition in microsatellite unstable colorectal cancers.
Vilar E, Bartnik CM, Stenzel SL, Raskin L, Ahn J, Moreno V, Mukherjee B, Iniesta MD, Morgan MA, Rennert G, Gruber SB
(2011) Cancer Res 71: 2632-42
MeSH Terms: Acid Anhydride Hydrolases, Benzimidazoles, Cell Line, Tumor, Colorectal Neoplasms, DNA Damage, DNA Repair Enzymes, DNA-Binding Proteins, Enzyme Inhibitors, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Gene Knockdown Techniques, Humans, MRE11 Homologue Protein, Microsatellite Instability, Mutation, Poly (ADP-Ribose) Polymerase-1, Poly(ADP-ribose) Polymerase Inhibitors, Poly(ADP-ribose) Polymerases, Rad51 Recombinase, Recombination, Genetic
Added March 5, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Enzymatic activity of methionine adenosyltransferase variants identified in patients with persistent hypermethioninemia.
Fernández-Irigoyen J, Santamaría E, Chien YH, Hwu WL, Korman SH, Faghfoury H, Schulze A, Hoganson GE, Stabler SP, Allen RH, Wagner C, Mudd SH, Corrales FJ
(2010) Mol Genet Metab 101: 172-7
MeSH Terms: Acid Anhydride Hydrolases, Adult, Amino Acid Metabolism, Inborn Errors, Humans, Infant, Infant, Newborn, Isoenzymes, Male, Methionine, Methionine Adenosyltransferase
Added January 20, 2015
0 Communities
1 Members
0 Resources
10 MeSH Terms
Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair.
Alt JR, Bouska A, Fernandez MR, Cerny RL, Xiao H, Eischen CM
(2005) J Biol Chem 280: 18771-81
MeSH Terms: Acid Anhydride Hydrolases, Amino Acid Sequence, Animals, Blotting, Western, Cell Cycle Proteins, Cell Line, Cell Line, Tumor, DNA Damage, DNA Repair, DNA Repair Enzymes, DNA, Complementary, DNA-Binding Proteins, Gamma Rays, Glutathione Transferase, HeLa Cells, Humans, Immunoprecipitation, K562 Cells, MRE11 Homologue Protein, Mice, Mice, Transgenic, Microscopy, Fluorescence, Molecular Sequence Data, Mutation, NIH 3T3 Cells, Nuclear Proteins, Protein Binding, Protein Structure, Tertiary, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-mdm2, Sequence Homology, Amino Acid, Silver Staining, Time Factors, Tumor Suppressor Protein p53
Added March 5, 2014
0 Communities
1 Members
0 Resources
34 MeSH Terms
CpG island methylation in Schistosoma- and non-Schistosoma-associated bladder cancer.
Gutiérrez MI, Siraj AK, Khaled H, Koon N, El-Rifai W, Bhatia K
(2004) Mod Pathol 17: 1268-74
MeSH Terms: Acid Anhydride Hydrolases, Adenomatous Polyposis Coli Protein, Apoptosis Regulatory Proteins, Cadherins, Calcium-Calmodulin-Dependent Protein Kinases, Carcinoma, Squamous Cell, Cell Cycle Proteins, CpG Islands, Cyclin-Dependent Kinase Inhibitor p15, Cyclin-Dependent Kinase Inhibitor p16, DNA Methylation, DNA-Binding Proteins, Death-Associated Protein Kinases, Genes, Tumor Suppressor, Glutathione S-Transferase pi, Glutathione Transferase, Humans, Isoenzymes, Neoplasm Proteins, Nuclear Proteins, O(6)-Methylguanine-DNA Methyltransferase, Polymerase Chain Reaction, Receptors, Retinoic Acid, Schistosomiasis haematobia, Tumor Protein p73, Tumor Suppressor Protein p14ARF, Tumor Suppressor Proteins, Urinary Bladder Neoplasms
Added March 5, 2014
0 Communities
1 Members
0 Resources
28 MeSH Terms
FHIT gene expression in human ovarian, endometrial, and cervical cancer cell lines.
Hendricks DT, Taylor R, Reed M, Birrer MJ
(1997) Cancer Res 57: 2112-5
MeSH Terms: Acid Anhydride Hydrolases, Blotting, Southern, Endometrial Neoplasms, Female, Gene Expression Regulation, Neoplastic, Humans, Neoplasm Proteins, Ovarian Neoplasms, Polymerase Chain Reaction, Proteins, RNA, Messenger, Sequence Analysis, DNA, Tumor Cells, Cultured, Uterine Cervical Neoplasms
Added August 14, 2013
0 Communities
0 Members
1 Resources
14 MeSH Terms