Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 10 of 28

Publication Record

Connections

Use of biological knowledge to inform the analysis of gene-gene interactions involved in modulating virologic failure with efavirenz-containing treatment regimens in ART-naïve ACTG clinical trials participants.
Grady BJ, Torstenson ES, McLaren PJ, DE Bakker PI, Haas DW, Robbins GK, Gulick RM, Haubrich R, Ribaudo H, Ritchie MD
(2011) Pac Symp Biocomput : 253-64
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 2, ATP-Binding Cassette Transporters, Alkynes, Anti-HIV Agents, Benzoxazines, Computational Biology, Cyclopropanes, Double-Blind Method, Drug Resistance, Viral, Epistasis, Genetic, Genome-Wide Association Study, HIV Infections, HIV-1, Humans, Polymorphism, Single Nucleotide, Potassium Channels, Inwardly Rectifying, Receptors, Drug, Risk Factors, Software, Sulfonylurea Receptors, Treatment Failure
Added March 13, 2015
0 Communities
1 Members
0 Resources
21 MeSH Terms
Pillars article: antigen presentation: discovery of the peptide TAP.
Van Kaer L
(2008) J Immunol 180: 2723-4
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 2, ATP Binding Cassette Transporter, Subfamily B, Member 3, ATP-Binding Cassette Transporters, Animals, Antigen Presentation, History, 20th Century, Humans, Membrane Transport Proteins, T-Lymphocytes, Cytotoxic
Added December 10, 2013
0 Communities
1 Members
0 Resources
9 MeSH Terms
Enhancement of dendritic cell antigen cross-presentation by CpG DNA involves type I IFN and stabilization of class I MHC mRNA.
Kuchtey J, Chefalo PJ, Gray RC, Ramachandra L, Harding CV
(2005) J Immunol 175: 2244-51
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 2, ATP-Binding Cassette Transporters, Adjuvants, Immunologic, Animals, Cells, Cultured, CpG Islands, Cross-Priming, Dendritic Cells, Half-Life, Histocompatibility Antigens Class I, Interferon-alpha, Interferon-beta, Mice, Mice, Inbred C57BL, Mice, Knockout, Oligodeoxyribonucleotides, Ovalbumin, RNA Stability, RNA, Messenger, Signal Transduction, Up-Regulation
Added February 19, 2015
0 Communities
1 Members
0 Resources
21 MeSH Terms
Hepatocytes express abundant surface class I MHC and efficiently use transporter associated with antigen processing, tapasin, and low molecular weight polypeptide proteasome subunit components of antigen processing and presentation pathway.
Chen M, Tabaczewski P, Truscott SM, Van Kaer L, Stroynowski I
(2005) J Immunol 175: 1047-55
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 2, ATP Binding Cassette Transporter, Subfamily B, Member 3, ATP-Binding Cassette Transporters, Animals, Antigen Presentation, Antiporters, Cell Membrane, Cells, Cultured, Cysteine Endopeptidases, Gene Expression Regulation, H-2 Antigens, Hepatocytes, Histocompatibility Antigen H-2D, Immunoglobulins, Listeriosis, Male, Membrane Transport Proteins, Mice, Mice, Inbred C57BL, Mice, Knockout, Multienzyme Complexes, Proteasome Endopeptidase Complex, Protein Processing, Post-Translational, Protein Subunits, Signal Transduction, Spleen
Added December 10, 2013
0 Communities
1 Members
0 Resources
26 MeSH Terms
Tapasin-/- and TAP1-/- macrophages are deficient in vacuolar alternate class I MHC (MHC-I) processing due to decreased MHC-I stability at phagolysosomal pH.
Chefalo PJ, Grandea AG, Van Kaer L, Harding CV
(2003) J Immunol 170: 5825-33
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 2, ATP-Binding Cassette Transporters, Acids, Animals, Antigen Presentation, Antigens, Bacterial, Antiporters, Cell Membrane, Cells, Cultured, Egg Proteins, Golgi Apparatus, H-2 Antigens, Half-Life, Hot Temperature, Hydrogen-Ion Concentration, Immunoglobulins, Macrophages, Membrane Transport Proteins, Mice, Mice, Inbred C57BL, Mice, Knockout, Ovalbumin, Peptide Fragments, Phagosomes, Temperature, Vacuoles
Added December 10, 2013
1 Communities
1 Members
0 Resources
26 MeSH Terms
Rejection of grafts with no H-2 disparity in TAP1 mutant mice: CD4 T cells are important effector cells and self H-2b class I molecules are target.
Suárez IM, Benvenutti LA, Noronh I, Van Kaer L, Kalil J, Coelho V
(2002) Transpl Immunol 9: 101-10
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 2, ATP-Binding Cassette Transporters, Amino Acid Sequence, Animals, CD4-Positive T-Lymphocytes, Cytokines, Graft Rejection, H-2 Antigens, Immunohistochemistry, Mice, Mice, Inbred C57BL, Mice, Knockout, Molecular Sequence Data, Skin Transplantation
Added December 10, 2013
0 Communities
1 Members
0 Resources
14 MeSH Terms
Tapasin enhances peptide-induced expression of H2-M3 molecules, but is not required for the retention of open conformers.
Lybarger L, Yu YY, Chun T, Wang CR, Grandea AG, Van Kaer L, Hansen TH
(2001) J Immunol 167: 2097-105
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 2, ATP Binding Cassette Transporter, Subfamily B, Member 3, ATP-Binding Cassette Transporters, Adjuvants, Immunologic, Animals, Antiporters, Cell Line, Transformed, Epitopes, H-2 Antigens, HeLa Cells, Histocompatibility Antigen H-2D, Histocompatibility Antigens Class I, Humans, Immunoglobulins, L Cells, Membrane Transport Proteins, Mice, Mutagenesis, Site-Directed, Peptides, Protein Binding, Protein Conformation, Transfection
Added December 10, 2013
1 Communities
1 Members
0 Resources
22 MeSH Terms
Functional roles of TAP and tapasin in the assembly of M3-N-formylated peptide complexes.
Chun T, Grandea AG, Lybarger L, Forman J, Van Kaer L, Wang CR
(2001) J Immunol 167: 1507-14
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 2, ATP Binding Cassette Transporter, Subfamily B, Member 3, ATP-Binding Cassette Transporters, Animals, Antigen Presentation, Antiporters, Binding, Competitive, Cell Line, Transformed, Endoplasmic Reticulum, Histocompatibility Antigens Class I, Histocompatibility Antigens Class II, Immunoglobulins, Macromolecular Substances, Membrane Transport Proteins, Mice, Mice, Inbred C57BL, Mice, Knockout, Molecular Chaperones, N-Formylmethionine, Peptides, Spleen, Tumor Cells, Cultured, beta 2-Microglobulin
Added December 10, 2013
1 Communities
1 Members
0 Resources
23 MeSH Terms
Accessory proteins that control the assembly of MHC molecules with peptides.
Van Kaer L
(2001) Immunol Res 23: 205-14
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 2, ATP Binding Cassette Transporter, Subfamily B, Member 3, ATP-Binding Cassette Transporters, Animals, Antigen Presentation, Antiporters, Calcium-Binding Proteins, Calnexin, Calreticulin, Cysteine Endopeptidases, Endoplasmic Reticulum, H-2 Antigens, HLA Antigens, HLA-D Antigens, Humans, Immunoglobulins, Interferon-gamma, Macromolecular Substances, Major Histocompatibility Complex, Membrane Transport Proteins, Mice, Mice, Knockout, Molecular Chaperones, Multienzyme Complexes, Peptide Fragments, Proteasome Endopeptidase Complex, Protein Transport, Proteins, Ribonucleoproteins, Viral Matrix Proteins
Added December 10, 2013
0 Communities
1 Members
0 Resources
30 MeSH Terms
Tapasin: an ER chaperone that controls MHC class I assembly with peptide.
Grandea AG, Van Kaer L
(2001) Trends Immunol 22: 194-9
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 2, ATP Binding Cassette Transporter, Subfamily B, Member 3, ATP-Binding Cassette Transporters, Animals, Antigen Presentation, Antiporters, Endoplasmic Reticulum, Histocompatibility Antigens Class I, Humans, Immunoglobulins, Membrane Transport Proteins, Molecular Chaperones, Peptides
Added December 10, 2013
0 Communities
1 Members
0 Resources
13 MeSH Terms