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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 43

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Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance.
Lee HH, Leake BF, Kim RB, Ho RH
(2017) Mol Pharmacol 91: 14-24
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 1, Animals, Biological Transport, Cell Membrane, Dogs, Doxorubicin, HeLa Cells, Humans, Kinetics, Liver, Liver-Specific Organic Anion Transporter 1, Madin Darby Canine Kidney Cells, Male, Mice, Models, Biological, Mutant Proteins, Organic Anion Transporters, Organic Anion Transporters, Sodium-Independent, Organic Cation Transport Proteins, Rats, Transfection
Added November 10, 2016
0 Communities
1 Members
0 Resources
21 MeSH Terms
Estrogen and insulin transport through the blood-brain barrier.
May AA, Bedel ND, Shen L, Woods SC, Liu M
(2016) Physiol Behav 163: 312-321
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 1, Animals, Blood Vessels, Blood-Brain Barrier, Body Weight, Brain, Dietary Fats, Estrogens, Female, Glucose Transporter Type 1, Insulin, Insulin Resistance, Male, Obesity, Ovariectomy, Rats, Rats, Long-Evans, Synaptophysin
Added March 2, 2017
0 Communities
1 Members
0 Resources
18 MeSH Terms
Contribution of hepatic organic anion-transporting polypeptides to docetaxel uptake and clearance.
Lee HH, Leake BF, Teft W, Tirona RG, Kim RB, Ho RH
(2015) Mol Cancer Ther 14: 994-1003
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 1, Animals, Antineoplastic Agents, Biological Transport, Cell Line, Tumor, Docetaxel, Humans, Liver, Liver-Specific Organic Anion Transporter 1, Male, Mice, Mice, Knockout, Organic Anion Transporters, Organic Anion Transporters, Sodium-Independent, Rats, Solute Carrier Organic Anion Transporter Family Member 1B3, Taxoids, Tubulin Modulators
Added February 25, 2015
0 Communities
2 Members
0 Resources
18 MeSH Terms
Genetic and non-genetic determinants of raltegravir penetration into cerebrospinal fluid: a single arm pharmacokinetic study.
Johnson DH, Sutherland D, Acosta EP, Erdem H, Richardson D, Haas DW
(2013) PLoS One 8: e82672
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, ATP Binding Cassette Transporter, Subfamily B, Member 1, Adult, Anti-HIV Agents, Blood-Brain Barrier, Female, Genetic Association Studies, Homozygote, Humans, Male, Middle Aged, Permeability, Polymorphism, Single Nucleotide, Pyrrolidinones, Raltegravir Potassium, Risk Factors
Added March 13, 2015
0 Communities
1 Members
0 Resources
16 MeSH Terms
7-Ketocholesterol induces P-glycoprotein through PI3K/mTOR signaling in hepatoma cells.
Wang SF, Chou YC, Mazumder N, Kao FJ, Nagy LD, Guengerich FP, Huang C, Lee HC, Lai PS, Ueng YF
(2013) Biochem Pharmacol 86: 548-60
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 1, Acetylcysteine, Antibiotics, Antineoplastic, Antioxidants, Carcinoma, Hepatocellular, Cell Line, Cell Line, Tumor, Cell Survival, Cholesterol, Doxorubicin, Drug Resistance, Neoplasm, Hepatocytes, Humans, Hydroxycholesterols, Ketocholesterols, Lactic Acid, Oligomycins, Phosphatidylinositol 3-Kinases, Phosphoinositide-3 Kinase Inhibitors, Signal Transduction, TOR Serine-Threonine Kinases, Up-Regulation
Added March 7, 2014
0 Communities
1 Members
0 Resources
22 MeSH Terms
On the origin of large flexibility of P-glycoprotein in the inward-facing state.
Wen PC, Verhalen B, Wilkens S, Mchaourab HS, Tajkhorshid E
(2013) J Biol Chem 288: 19211-20
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 1, Adenosine Triphosphate, Animals, Biological Transport, Cell Membrane, Electron Spin Resonance Spectroscopy, Lipids, Mice, Molecular Dynamics Simulation, Protein Binding, Protein Structure, Tertiary, Substrate Specificity
Added February 19, 2015
0 Communities
1 Members
0 Resources
12 MeSH Terms
miR-33 controls the expression of biliary transporters, and mediates statin- and diet-induced hepatotoxicity.
Allen RM, Marquart TJ, Albert CJ, Suchy FJ, Wang DQ, Ananthanarayanan M, Ford DA, Baldán A
(2012) EMBO Mol Med 4: 882-95
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 11, ATP-Binding Cassette Transporters, Adenosine Triphosphatases, Animals, Bile, Cells, Cultured, Diet, Gene Expression Regulation, Hepatocytes, Liver, Male, Mice, Mice, Inbred C57BL, MicroRNAs, Models, Biological, Phospholipid Transfer Proteins, Simvastatin
Added February 12, 2016
0 Communities
1 Members
0 Resources
17 MeSH Terms
Predicting clopidogrel response using DNA samples linked to an electronic health record.
Delaney JT, Ramirez AH, Bowton E, Pulley JM, Basford MA, Schildcrout JS, Shi Y, Zink R, Oetjens M, Xu H, Cleator JH, Jahangir E, Ritchie MD, Masys DR, Roden DM, Crawford DC, Denny JC
(2012) Clin Pharmacol Ther 91: 257-63
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, ATP Binding Cassette Transporter, Subfamily B, Member 1, Aged, Aryl Hydrocarbon Hydroxylases, Aryldialkylphosphatase, Clopidogrel, Cytochrome P-450 CYP2C19, Databases, Nucleic Acid, Electronic Health Records, Female, Genotype, Humans, Male, Myocardial Infarction, Pharmacogenetics, Platelet Aggregation Inhibitors, Polymorphism, Genetic, Stents, Thrombosis, Ticlopidine, Treatment Outcome
Added December 10, 2013
0 Communities
5 Members
0 Resources
21 MeSH Terms
The use of a DNA biobank linked to electronic medical records to characterize pharmacogenomic predictors of tacrolimus dose requirement in kidney transplant recipients.
Birdwell KA, Grady B, Choi L, Xu H, Bian A, Denny JC, Jiang M, Vranic G, Basford M, Cowan JD, Richardson DM, Robinson MP, Ikizler TA, Ritchie MD, Stein CM, Haas DW
(2012) Pharmacogenet Genomics 22: 32-42
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, ATP Binding Cassette Transporter, Subfamily B, Member 1, Adult, Age Factors, Body Weight, Cytochrome P-450 CYP3A, Databases, Nucleic Acid, Dose-Response Relationship, Drug, Drug Monitoring, Electronic Health Records, Female, Genetic Association Studies, Genotype, Hemoglobins, Humans, Immunosuppressive Agents, Kidney Transplantation, Linkage Disequilibrium, Male, Middle Aged, Polymorphism, Single Nucleotide, Pregnane X Receptor, Receptors, Steroid, Tacrolimus
Added December 10, 2013
0 Communities
6 Members
0 Resources
24 MeSH Terms
Modulation of drug block of the cardiac potassium channel KCNA5 by the drug transporters OCTN1 and MDR1.
Yang T, McBride BF, Leake BF, Kim RB, Roden DM
(2010) Br J Pharmacol 161: 1023-33
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, ATP Binding Cassette Transporter, Subfamily B, Member 1, Animals, Anti-Arrhythmia Agents, Binding Sites, Biological Transport, CHO Cells, Cell Line, Cricetinae, Cricetulus, Gene Expression Regulation, Humans, Kv1.5 Potassium Channel, Organic Cation Transport Proteins, Protein Binding, Swine, Symporters
Added March 7, 2014
1 Communities
2 Members
2 Resources
17 MeSH Terms