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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 33

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TGFβ loss activates ADAMTS-1-mediated EGF-dependent invasion in a model of esophageal cell invasion.
Le Bras GF, Taylor C, Koumangoye RB, Revetta F, Loomans HA, Andl CD
(2015) Exp Cell Res 330: 29-42
MeSH Terms: ADAM Proteins, ADAMTS1 Protein, Carcinoma, Squamous Cell, Cell Line, Tumor, Cell Movement, Cell Proliferation, Esophageal Neoplasms, Fibroblasts, Heparin-binding EGF-like Growth Factor, Humans, Interleukin-1, Keratinocytes, Nerve Tissue Proteins, Receptors, Immunologic, Receptors, Transforming Growth Factor beta, Transforming Growth Factor alpha, Transforming Growth Factor beta
Added October 13, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms
Genetic variants of Adam17 differentially regulate TGFβ signaling to modify vascular pathology in mice and humans.
Kawasaki K, Freimuth J, Meyer DS, Lee MM, Tochimoto-Okamoto A, Benzinou M, Clermont FF, Wu G, Roy R, Letteboer TG, Ploos van Amstel JK, Giraud S, Dupuis-Girod S, Lesca G, Westermann CJ, Coffey RJ, Akhurst RJ
(2014) Proc Natl Acad Sci U S A 111: 7723-8
MeSH Terms: ADAM Proteins, ADAM17 Protein, Animals, Blood Vessels, Gene Expression Regulation, Genetic Variation, Humans, Immunohistochemistry, Luciferases, Mice, Mice, Inbred C57BL, NIH 3T3 Cells, Signal Transduction, Smad2 Protein, Transforming Growth Factor beta, Transforming Growth Factor beta1
Added February 19, 2015
0 Communities
1 Members
0 Resources
16 MeSH Terms
Novel mechanistic insights into ectodomain shedding of EGFR Ligands Amphiregulin and TGF-α: impact on gastrointestinal cancers driven by secondary bile acids.
Nagathihalli NS, Beesetty Y, Lee W, Washington MK, Chen X, Lockhart AC, Merchant NB
(2014) Cancer Res 74: 2062-72
MeSH Terms: ADAM Proteins, ADAM17 Protein, Amphiregulin, Bile Acids and Salts, Cyclin D1, Deoxycholic Acid, EGF Family of Proteins, ErbB Receptors, Gastrointestinal Neoplasms, Glycoproteins, HCT116 Cells, Humans, Intercellular Signaling Peptides and Proteins, Pancreas, Phosphorylation, Receptors, G-Protein-Coupled, STAT3 Transcription Factor, Transforming Growth Factor alpha, src-Family Kinases
Added February 14, 2014
0 Communities
3 Members
0 Resources
19 MeSH Terms
ALCAM/CD166 is a TGF-β-responsive marker and functional regulator of prostate cancer metastasis to bone.
Hansen AG, Arnold SA, Jiang M, Palmer TD, Ketova T, Merkel A, Pickup M, Samaras S, Shyr Y, Moses HL, Hayward SW, Sterling JA, Zijlstra A
(2014) Cancer Res 74: 1404-15
MeSH Terms: ADAM Proteins, ADAM17 Protein, Antigens, CD, Biomarkers, Tumor, Bone and Bones, Caspase 3, Cell Adhesion Molecules, Neuronal, Cell Line, Tumor, Cell Movement, Cell Proliferation, Cell Survival, Cellular Microenvironment, Disease Progression, Fetal Proteins, Humans, Male, Neoplasm Metastasis, Prostatic Neoplasms, Transforming Growth Factor beta
Added February 17, 2014
1 Communities
6 Members
0 Resources
19 MeSH Terms
A Lactobacillus rhamnosus GG-derived soluble protein, p40, stimulates ligand release from intestinal epithelial cells to transactivate epidermal growth factor receptor.
Yan F, Liu L, Dempsey PJ, Tsai YH, Raines EW, Wilson CL, Cao H, Cao Z, Liu L, Polk DB
(2013) J Biol Chem 288: 30742-30751
MeSH Terms: ADAM Proteins, ADAM17 Protein, Animals, Bacterial Proteins, Cell Line, Tumor, Enzyme Activation, Epithelial Cells, ErbB Receptors, Gene Expression Regulation, Enzymologic, Gene Knockdown Techniques, Heparin-binding EGF-like Growth Factor, Humans, Intercellular Signaling Peptides and Proteins, Intestinal Mucosa, Lactobacillus rhamnosus, Mice, Mice, Knockout, Probiotics, Proto-Oncogene Proteins c-akt, Transcriptional Activation, Transforming Growth Factor alpha, Up-Regulation
Added May 19, 2014
0 Communities
1 Members
0 Resources
22 MeSH Terms
miR-335 and miR-363 regulation of neuroblastoma tumorigenesis and metastasis.
Qiao J, Lee S, Paul P, Theiss L, Tiao J, Qiao L, Kong A, Chung DH
(2013) Surgery 154: 226-33
MeSH Terms: ADAM Proteins, Animals, Cell Line, Tumor, Cell Transformation, Neoplastic, Humans, Liver Neoplasms, Experimental, Male, Membrane Proteins, Mice, MicroRNAs, Neoplasm Invasiveness, Neuroblastoma, Receptors, Bombesin
Added March 7, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Management and outcomes for patients with TTP: analysis of 100 cases at a single institution.
Chaturvedi S, Carcioppolo D, Zhang L, McCrae KR
(2013) Am J Hematol 88: 560-5
MeSH Terms: ADAM Proteins, ADAMTS13 Protein, Adolescent, Adult, Age Factors, Aged, Disease Management, Disease Progression, Female, Humans, L-Lactate Dehydrogenase, Longitudinal Studies, Male, Middle Aged, Multivariate Analysis, Plasma Exchange, Purpura, Thrombotic Thrombocytopenic, Risk Factors, Survival Analysis, Treatment Outcome
Added August 1, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
Screening ADAMTS10 in dog populations supports Gly661Arg as the glaucoma-causing variant in beagles.
Kuchtey J, Kunkel J, Esson D, Sapienza JS, Ward DA, Plummer CE, Gelatt KN, Kuchtey RW
(2013) Invest Ophthalmol Vis Sci 54: 1881-6
MeSH Terms: ADAM Proteins, ADAMTS Proteins, Alleles, Animals, DNA, DNA Mutational Analysis, Dogs, Gene Frequency, Genetic Predisposition to Disease, Genetic Testing, Genotype, Glaucoma, Open-Angle, Intraocular Pressure, Mutation, Polymorphism, Single Nucleotide
Added February 19, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
EGF receptor is required for KRAS-induced pancreatic tumorigenesis.
Ardito CM, Grüner BM, Takeuchi KK, Lubeseder-Martellato C, Teichmann N, Mazur PK, Delgiorno KE, Carpenter ES, Halbrook CJ, Hall JC, Pal D, Briel T, Herner A, Trajkovic-Arsic M, Sipos B, Liou GY, Storz P, Murray NR, Threadgill DW, Sibilia M, Washington MK, Wilson CL, Schmid RM, Raines EW, Crawford HC, Siveke JT
(2012) Cancer Cell 22: 304-17
MeSH Terms: ADAM Proteins, ADAM17 Protein, Animals, Carcinoma, Pancreatic Ductal, Cell Line, Tumor, Cell Transformation, Neoplastic, Epithelial Cells, ErbB Receptors, Extracellular Signal-Regulated MAP Kinases, Genes, ras, Humans, Mice, Mice, Transgenic, Pancreas, Pancreatic Neoplasms, Proto-Oncogene Proteins p21(ras)
Added April 12, 2016
0 Communities
2 Members
0 Resources
16 MeSH Terms
Prediction of hepatocellular carcinoma development by plasma ADAMTS13 in chronic hepatitis B and C.
Ikeda H, Tateishi R, Enooku K, Yoshida H, Nakagawa H, Masuzaki R, Kondo Y, Goto T, Shiina S, Kume Y, Tomiya T, Inoue Y, Nishikawa T, Ohtomo N, Tanoue Y, Ono T, Koike K, Yatomi Y
(2011) Cancer Epidemiol Biomarkers Prev 20: 2204-11
MeSH Terms: ADAM Proteins, ADAMTS13 Protein, Aged, Alanine Transaminase, Aspartate Aminotransferases, Biomarkers, Tumor, Blood Proteins, Carcinoma, Hepatocellular, Case-Control Studies, Enzyme-Linked Immunosorbent Assay, Female, Follow-Up Studies, Hepacivirus, Hepatic Stellate Cells, Hepatitis B virus, Hepatitis B, Chronic, Hepatitis C, Chronic, Humans, Liver Neoplasms, Male, Middle Aged, Neoplasm Recurrence, Local, Prognosis
Added May 2, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms