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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 12

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Human DNA polymerase η accommodates RNA for strand extension.
Su Y, Egli M, Guengerich FP
(2017) J Biol Chem 292: 18044-18051
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Base Pair Mismatch, DNA Primers, DNA Replication, DNA-Directed DNA Polymerase, Deoxyguanosine, Electrophoretic Mobility Shift Assay, Humans, Kinetics, Nucleic Acid Heteroduplexes, Nucleic Acid Hybridization, Oligodeoxyribonucleotides, Oligoribonucleotides, Pyrimidine Dimers, RNA, Recombinant Proteins, Reverse Transcription, Substrate Specificity, Transcription Elongation, Genetic
Added March 14, 2018
0 Communities
1 Members
0 Resources
19 MeSH Terms
The Role of Biomarkers of Oxidative Stress in Breast Cancer Risk and Prognosis: A Systematic Review of the Epidemiologic Literature.
Lee JD, Cai Q, Shu XO, Nechuta SJ
(2017) J Womens Health (Larchmt) 26: 467-482
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Adult, Biomarkers, Tumor, Breast Neoplasms, Deoxyguanosine, Female, Humans, Middle Aged, Oxidative Stress, Prognosis, Risk Factors, Survival Analysis
Added May 19, 2017
0 Communities
2 Members
0 Resources
12 MeSH Terms
Kinetic analysis of bypass of 7,8-dihydro-8-oxo-2'-deoxyguanosine by the catalytic core of yeast DNA polymerase η.
Xue Q, Zhong M, Liu B, Tang Y, Wei Z, Guengerich FP, Zhang H
(2016) Biochimie 121: 161-9
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Catalytic Domain, DNA-Directed DNA Polymerase, Deoxyguanosine, Kinetics, Pyrimidine Nucleotides
Added March 14, 2018
0 Communities
1 Members
0 Resources
6 MeSH Terms
Roles of Residues Arg-61 and Gln-38 of Human DNA Polymerase η in Bypass of Deoxyguanosine and 7,8-Dihydro-8-oxo-2'-deoxyguanosine.
Su Y, Patra A, Harp JM, Egli M, Guengerich FP
(2015) J Biol Chem 290: 15921-33
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Amino Acid Motifs, Catalytic Domain, Crystallography, X-Ray, DNA, DNA Replication, DNA-Directed DNA Polymerase, Deoxyguanosine, Humans, Mutagenesis, Site-Directed, Substrate Specificity
Added March 14, 2018
0 Communities
1 Members
0 Resources
11 MeSH Terms
Dietary selenium deficiency exacerbates DSS-induced epithelial injury and AOM/DSS-induced tumorigenesis.
Barrett CW, Singh K, Motley AK, Lintel MK, Matafonova E, Bradley AM, Ning W, Poindexter SV, Parang B, Reddy VK, Chaturvedi R, Fingleton BM, Washington MK, Wilson KT, Davies SS, Hill KE, Burk RF, Williams CS
(2013) PLoS One 8: e67845
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Animals, Azoxymethane, Carcinogenesis, Colitis, Colonic Neoplasms, DNA Damage, Deoxyguanosine, Dextran Sulfate, Diet, Epidermal Growth Factor, Gene Expression Regulation, Inflammation, Mice, Mice, Inbred C57BL, Selenium, Signal Transduction, Transforming Growth Factor beta, Weight Loss
Added March 5, 2014
3 Communities
8 Members
0 Resources
19 MeSH Terms
Comparison of three oxidative stress biomarkers in a sample of healthy adults.
Watters JL, Satia JA, da Costa KA, Boysen G, Collins LB, Morrow JD, Milne GL, Swenberg JA
(2009) Biomarkers 14: 587-95
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Adult, Biomarkers, Comet Assay, DNA Damage, DNA-Formamidopyrimidine Glycosylase, Deoxyguanosine, F2-Isoprostanes, Female, Humans, Lipid Peroxidation, Male, Middle Aged, Oxidative Stress
Added March 26, 2014
1 Communities
1 Members
0 Resources
14 MeSH Terms
Structural and functional elucidation of the mechanism promoting error-prone synthesis by human DNA polymerase kappa opposite the 7,8-dihydro-8-oxo-2'-deoxyguanosine adduct.
Irimia A, Eoff RL, Guengerich FP, Egli M
(2009) J Biol Chem 284: 22467-22480
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Base Sequence, Catalysis, DNA Replication, DNA-Directed DNA Polymerase, Deoxyguanosine, Fungal Proteins, Humans, Kinetics, Models, Biological, Molecular Conformation, Molecular Sequence Data, Mutation, Protein Structure, Tertiary, Sulfolobus, X-Ray Diffraction
Added March 26, 2014
0 Communities
2 Members
0 Resources
16 MeSH Terms
Hydrogen bonding of 7,8-dihydro-8-oxodeoxyguanosine with a charged residue in the little finger domain determines miscoding events in Sulfolobus solfataricus DNA polymerase Dpo4.
Eoff RL, Irimia A, Angel KC, Egli M, Guengerich FP
(2007) J Biol Chem 282: 19831-43
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Amino Acid Substitution, Archaeal Proteins, Crystallography, X-Ray, DNA Polymerase beta, DNA, Archaeal, Deoxyguanosine, Hydrogen Bonding, Mutation, Missense, Protein Structure, Tertiary, Sulfolobus solfataricus
Added March 5, 2014
0 Communities
2 Members
0 Resources
11 MeSH Terms
Efficient and high fidelity incorporation of dCTP opposite 7,8-dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA polymerase Dpo4.
Zang H, Irimia A, Choi JY, Angel KC, Loukachevitch LV, Egli M, Guengerich FP
(2006) J Biol Chem 281: 2358-72
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Base Sequence, Chromatography, Liquid, DNA, DNA Primers, DNA-Directed DNA Polymerase, Deoxycytosine Nucleotides, Deoxyguanosine, Dose-Response Relationship, Drug, Escherichia coli, Frameshift Mutation, Kinetics, Mass Spectrometry, Models, Molecular, Molecular Sequence Data, Protein Binding, Sulfolobus solfataricus, Time Factors, X-Ray Diffraction
Added March 5, 2014
0 Communities
2 Members
0 Resources
19 MeSH Terms
Effects of age and caloric restriction on lipid peroxidation: measurement of oxidative stress by F2-isoprostane levels.
Ward WF, Qi W, Van Remmen H, Zackert WE, Roberts LJ, Richardson A
(2005) J Gerontol A Biol Sci Med Sci 60: 847-51
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Age Factors, Aging, Animal Nutritional Physiological Phenomena, Animals, Biomarkers, Caloric Restriction, Chromatography, High Pressure Liquid, Chromatography, Thin Layer, DNA, Deoxyguanosine, F2-Isoprostanes, Gas Chromatography-Mass Spectrometry, Kidney, Lipid Peroxidation, Liver, Male, Oxidative Stress, Rats, Rats, Inbred F344
Added December 10, 2013
0 Communities
1 Members
0 Resources
20 MeSH Terms