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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 31

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Epoxygenated Fatty Acids Inhibit Retinal Vascular Inflammation.
Capozzi ME, Hammer SS, McCollum GW, Penn JS
(2016) Sci Rep 6: 39211
MeSH Terms: 8,11,14-Eicosatrienoic Acid, Adamantane, Animals, Cells, Cultured, Disease Models, Animal, Down-Regulation, Endothelial Cells, Epoxy Compounds, Fatty Acids, Unsaturated, Humans, Intercellular Adhesion Molecule-1, Lauric Acids, Male, Mice, Retinal Vasculitis, Retinal Vessels, Tumor Necrosis Factor-alpha, Vascular Cell Adhesion Molecule-1
Added April 10, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Epoxyeicosatrienoic acids and glucose homeostasis in mice and men.
Luther JM, Brown NJ
(2016) Prostaglandins Other Lipid Mediat 125: 2-7
MeSH Terms: 8,11,14-Eicosatrienoic Acid, Animals, Diabetes Mellitus, Type 2, Glucose, Homeostasis, Humans, Insulin Resistance, Mice, Signal Transduction
Added April 6, 2017
0 Communities
2 Members
0 Resources
9 MeSH Terms
Lipoxygenase-catalyzed transformation of epoxy fatty acids to hydroxy-endoperoxides: a potential P450 and lipoxygenase interaction.
Teder T, Boeglin WE, Brash AR
(2014) J Lipid Res 55: 2587-96
MeSH Terms: 8,11,14-Eicosatrienoic Acid, Animals, Arachidonate 12-Lipoxygenase, Arachidonate 15-Lipoxygenase, Biocatalysis, Blood Platelets, Chromatography, High Pressure Liquid, Eicosanoids, Epoxy Compounds, Gas Chromatography-Mass Spectrometry, Humans, Hydroxylation, Linolenic Acids, Lipid Peroxides, Lipoxygenase, Mice, Molecular Structure, Nuclear Magnetic Resonance, Biomolecular, Oxidation-Reduction, Recombinant Proteins, Soybean Proteins, Spectrometry, Mass, Electrospray Ionization, Stereoisomerism
Added January 21, 2015
0 Communities
1 Members
0 Resources
23 MeSH Terms
The importance of the lipoxygenase-hepoxilin pathway in the mammalian epidermal barrier.
Muñoz-Garcia A, Thomas CP, Keeney DS, Zheng Y, Brash AR
(2014) Biochim Biophys Acta 1841: 401-8
MeSH Terms: 8,11,14-Eicosatrienoic Acid, Animals, Arachidonate 12-Lipoxygenase, Ceramides, Epidermis, Humans, Lipid Metabolism, Lipoxygenase
Added March 7, 2014
0 Communities
1 Members
0 Resources
8 MeSH Terms
Epoxyeicosatrienoic acids (EETs) regulate epithelial sodium channel activity by extracellular signal-regulated kinase 1/2 (ERK1/2)-mediated phosphorylation.
Pidkovka N, Rao R, Mei S, Gong Y, Harris RC, Wang WH, Capdevila JH
(2013) J Biol Chem 288: 5223-31
MeSH Terms: 8,11,14-Eicosatrienoic Acid, Animals, Antibodies, Monoclonal, Antibodies, Monoclonal, Humanized, Antihypertensive Agents, Cetuximab, Cytochrome P-450 Enzyme System, Cytochrome P450 Family 2, Epidermal Growth Factor, Epithelial Sodium Channels, Extracellular Signal-Regulated MAP Kinases, Gene Expression Regulation, Humans, Hypertension, Kidney, Male, Mice, Models, Biological, Phosphorylation
Added August 19, 2013
1 Communities
1 Members
0 Resources
19 MeSH Terms
8R-Lipoxygenase-catalyzed synthesis of a prominent cis-epoxyalcohol from dihomo-γ-linolenic acid: a distinctive transformation compared with S-lipoxygenases.
Jin J, Boeglin WE, Cha JK, Brash AR
(2012) J Lipid Res 53: 292-9
MeSH Terms: 8,11,14-Eicosatrienoic Acid, Animals, Anthozoa, Arachidonate Lipoxygenases, Epoxy Compounds, Gas Chromatography-Mass Spectrometry, Intramolecular Oxidoreductases, Lipoxygenase, Magnetic Resonance Spectroscopy, Substrate Specificity
Added December 10, 2013
0 Communities
1 Members
0 Resources
10 MeSH Terms
EET signaling in cancer.
Panigrahy D, Greene ER, Pozzi A, Wang DW, Zeldin DC
(2011) Cancer Metastasis Rev 30: 525-40
MeSH Terms: 8,11,14-Eicosatrienoic Acid, Animals, Cell Transformation, Neoplastic, Cytochrome P-450 Enzyme System, Humans, Inflammation, Neoplasms, Neovascularization, Pathologic, Signal Transduction, Tumor Microenvironment
Added February 24, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Streptomyces coelicolor A3(2) CYP102 protein, a novel fatty acid hydroxylase encoded as a heme domain without an N-terminal redox partner.
Lamb DC, Lei L, Zhao B, Yuan H, Jackson CJ, Warrilow AG, Skaug T, Dyson PJ, Dawson ES, Kelly SL, Hachey DL, Waterman MR
(2010) Appl Environ Microbiol 76: 1975-80
MeSH Terms: 8,11,14-Eicosatrienoic Acid, Arachidonic Acid, Cloning, Molecular, Cytochrome P-450 Enzyme System, DNA Transposable Elements, Escherichia coli, Ferredoxin-NADP Reductase, Ferredoxins, Gene Expression, Mixed Function Oxygenases, Mutagenesis, Insertional, NADP, Streptomyces coelicolor, Substrate Specificity
Added March 20, 2014
0 Communities
2 Members
0 Resources
14 MeSH Terms
Epidermal lipoxygenase products of the hepoxilin pathway selectively activate the nuclear receptor PPARalpha.
Yu Z, Schneider C, Boeglin WE, Brash AR
(2007) Lipids 42: 491-7
MeSH Terms: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid, 8,11,14-Eicosatrienoic Acid, Arachidonate Lipoxygenases, Cell Differentiation, Cell Line, Epidermal Cells, Epidermis, Genes, Reporter, Humans, Hydroxyeicosatetraenoic Acids, Lipoxygenase, Luciferases, PPAR alpha, PPAR delta, PPAR gamma, Receptors, Cytoplasmic and Nuclear, Signal Transduction
Added December 10, 2013
0 Communities
2 Members
0 Resources
17 MeSH Terms
Mitogenic activity and signaling mechanism of 2-(14,15- epoxyeicosatrienoyl)glycerol, a novel cytochrome p450 arachidonate metabolite.
Chen J, Chen JK, Falck JR, Guthi JS, Anjaiah S, Capdevila JH, Harris RC
(2007) Mol Cell Biol 27: 3023-34
MeSH Terms: 8,11,14-Eicosatrienoic Acid, ADAM Proteins, ADAM17 Protein, Animals, Arachidonic Acid, Cell Line, Cytochrome P-450 Enzyme System, Down-Regulation, Enzyme Activation, Epidermal Growth Factor, Epithelial Cells, ErbB Receptors, Extracellular Signal-Regulated MAP Kinases, Gene Expression Regulation, Enzymologic, Glycerol, Heparin-binding EGF-like Growth Factor, Intercellular Signaling Peptides and Proteins, Kidney Tubules, Proximal, Membrane Proteins, Mitogens, Models, Biological, Monoglycerides, RNA, Small Interfering, Receptors, Cannabinoid, Signal Transduction, Swine, Transforming Growth Factor alpha
Added August 19, 2013
1 Communities
1 Members
0 Resources
27 MeSH Terms