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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 19

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A single intramuscular injection of rAAV-mediated mutant erythropoietin protects against MPTP-induced parkinsonism.
Dhanushkodi A, Akano EO, Roguski EE, Xue Y, Rao SK, Matta SG, Rex TS, McDonald MP
(2013) Genes Brain Behav 12: 224-33
MeSH Terms: 3,4-Dihydroxyphenylacetic Acid, Animals, Corpus Striatum, Dependovirus, Dopamine, Erythropoietin, Genetic Therapy, Genetic Vectors, Hypokinesia, Injections, Intramuscular, Locomotion, MPTP Poisoning, Male, Mice, Mice, Inbred C57BL, Mutation, Missense, Neurons, Substantia Nigra, Tremor
Added January 20, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms
Prostaglandin E2-mediated attenuation of mesocortical dopaminergic pathway is critical for susceptibility to repeated social defeat stress in mice.
Tanaka K, Furuyashiki T, Kitaoka S, Senzai Y, Imoto Y, Segi-Nishida E, Deguchi Y, Breyer RM, Breyer MD, Narumiya S
(2012) J Neurosci 32: 4319-29
MeSH Terms: 3,4-Dihydroxyphenylacetic Acid, Analysis of Variance, Animals, Benzazepines, Calcium-Binding Proteins, Corticosterone, Cyclooxygenase 1, Cyclooxygenase 2, Cyclooxygenase Inhibitors, Dinoprostone, Disease Models, Animal, Disease Susceptibility, Dominance-Subordination, Dopamine, Dopamine Antagonists, Homovanillic Acid, Interpersonal Relations, Maze Learning, Membrane Proteins, Mice, Mice, Inbred C57BL, Mice, Inbred ICR, Mice, Knockout, Microfilament Proteins, Neural Pathways, Oxidopamine, Prefrontal Cortex, Pyrazoles, Receptors, Prostaglandin E, Signal Transduction, Stress, Psychological, Sulfonamides, Time Factors, Tyrosine 3-Monooxygenase, Ventral Tegmental Area
Added December 21, 2013
1 Communities
1 Members
0 Resources
35 MeSH Terms
The metabotropic glutamate receptor 4-positive allosteric modulator VU0364770 produces efficacy alone and in combination with L-DOPA or an adenosine 2A antagonist in preclinical rodent models of Parkinson's disease.
Jones CK, Bubser M, Thompson AD, Dickerson JW, Turle-Lorenzo N, Amalric M, Blobaum AL, Bridges TM, Morrison RD, Jadhav S, Engers DW, Italiano K, Bode J, Daniels JS, Lindsley CW, Hopkins CR, Conn PJ, Niswender CM
(2012) J Pharmacol Exp Ther 340: 404-21
MeSH Terms: 3,4-Dihydroxyphenylacetic Acid, Adenosine A2 Receptor Antagonists, Animals, Brain, Calcium Signaling, Catalepsy, Corpus Striatum, Disease Models, Animal, Dose-Response Relationship, Drug, Drug Synergism, Drug Therapy, Combination, G Protein-Coupled Inwardly-Rectifying Potassium Channels, Glutamic Acid, HEK293 Cells, Haloperidol, Humans, Levodopa, Male, Monoamine Oxidase, Motor Neuron Disease, Oxidopamine, Parkinson Disease, Picolinic Acids, Protein Binding, Psychomotor Performance, Pyrimidines, Rats, Rats, Sprague-Dawley, Rats, Wistar, Reaction Time, Receptors, G-Protein-Coupled, Receptors, Metabotropic Glutamate, Substantia Nigra, Thallium, Transfection, Triazoles, Tyrosine 3-Monooxygenase
Added February 19, 2015
0 Communities
3 Members
0 Resources
37 MeSH Terms
Neuroleptics increase striatal catecholamine metabolites but not ascorbic acid in dialyzed perfusate.
Blakely RD, Wages SA, Justice JB, Herndon JG, Neill DB
(1984) Brain Res 308: 1-8
MeSH Terms: 3,4-Dihydroxyphenylacetic Acid, Animals, Ascorbic Acid, Catecholamines, Catheterization, Clozapine, Corpus Striatum, Dibenzazepines, Haloperidol, Homovanillic Acid, Hydroxyindoleacetic Acid, Kinetics, Male, Perfusion, Rats, Rats, Inbred Strains
Added July 10, 2013
1 Communities
1 Members
0 Resources
16 MeSH Terms
Footshock and conditioned stress increase 3,4-dihydroxyphenylacetic acid (DOPAC) in the ventral tegmental area but not substantia nigra.
Deutch AY, Tam SY, Roth RH
(1985) Brain Res 333: 143-6
MeSH Terms: 3,4-Dihydroxyphenylacetic Acid, Animals, Dopamine, Electroshock, Fear, Frontal Lobe, Limbic System, Male, Phenylacetates, Rats, Stress, Physiological, Substantia Nigra, Tegmentum Mesencephali
Added May 27, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Mesolimbic and mesocortical dopamine activation induced by phencyclidine: contrasting pattern to striatal response.
Deutch AY, Tam SY, Freeman AS, Bowers MB, Roth RH
(1987) Eur J Pharmacol 134: 257-64
MeSH Terms: 3,4-Dihydroxyphenylacetic Acid, Animals, Biotransformation, Cerebral Cortex, Corpus Striatum, Dopamine, Homovanillic Acid, Limbic System, Male, Norepinephrine, Phencyclidine, Rats, Rats, Inbred Strains
Added May 27, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Calcitonin gene-related peptide in the ventral tegmental area: selective modulation of prefrontal cortical dopamine metabolism.
Deutch AY, Roth RH
(1987) Neurosci Lett 74: 169-74
MeSH Terms: 3,4-Dihydroxyphenylacetic Acid, Animals, Calcitonin Gene-Related Peptide, Cerebral Cortex, Corpus Striatum, Dopamine, Frontal Lobe, Immunoenzyme Techniques, Limbic System, Neural Pathways, Neuropeptides, Rats, Tegmentum Mesencephali
Added May 27, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on catecholamines and metabolites in primate brain and CSF.
Elsworth JD, Deutch AY, Redmond DE, Sladek JR, Roth RH
(1987) Brain Res 415: 293-9
MeSH Terms: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine, 3,4-Dihydroxyphenylacetic Acid, Animals, Catecholamines, Chlorocebus aethiops, Corpus Striatum, Dopamine, Homovanillic Acid, Male, Methoxyhydroxyphenylglycol, Pyridines, Tegmentum Mesencephali
Added May 27, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Differential responsiveness to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in sub-regions of the primate substantia nigra and striatum.
Elsworth JD, Deutch AY, Redmond DE, Sladek JR, Roth RH
(1987) Life Sci 40: 193-202
MeSH Terms: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine, 3,4-Dihydroxyphenylacetic Acid, Animals, Caudate Nucleus, Chlorocebus aethiops, Corpus Striatum, Dopamine, Homovanillic Acid, Male, Neurotoxins, Norepinephrine, Pyridines, Substantia Nigra
Added May 27, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Stress and the mesocorticolimbic dopamine systems.
Roth RH, Tam SY, Ida Y, Yang JX, Deutch AY
(1988) Ann N Y Acad Sci 537: 138-47
MeSH Terms: 3,4-Dihydroxyphenylacetic Acid, Animals, Carbolines, Cerebral Cortex, Chromatography, High Pressure Liquid, Dopamine, Electroshock, Frontal Lobe, Gas Chromatography-Mass Spectrometry, Homovanillic Acid, Limbic System, Male, Mesencephalon, Neurons, Neurons, Afferent, Rats, Rats, Inbred Strains, Stress, Physiological
Added May 27, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms