Keyword Connections

•  Kasey Vickers

•  Larry Swift

•  Valentina Kon

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Communities

• Metabolism Interest Group

Publications

• Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia.
  Beigneux AP, Miyashita K, Ploug M, Blom DJ, Ai M, Linton MF, Khovidhunkit W, Dufour R, Garg A, McMahon MA, Pullinger CR, Sandoval NP, Hu X, Allan CM, Larsson M, Machida T, Murakami M, Reue K, Tontonoz P, Goldberg IJ, Moulin P, Charrière S, Fong LG, Nakajima K, Young SG
  (2017) N Engl J Med 376: 1647-1658
• Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease.
  Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators, Stitziel NO, Stirrups KE, Masca NG, Erdmann J, Ferrario PG, König IR, Weeke PE, Webb TR, Auer PL, Schick UM, Lu Y, Zhang H, Dube MP, Goel A, Farrall M, Peloso GM, Won HH, Do R, van Iperen E, Kanoni S, Kruppa J, Mahajan A, Scott RA, Willenberg C, Braund PS, van Capelleveen JC, Doney AS, Donnelly LA, Asselta R, Merlini PA, Duga S, Marziliano N, Denny JC, Shaffer CM, El-Mokhtari NE, Franke A, Gottesman O, Heilmann S, Hengstenberg C, Hoffman P, Holmen OL, Hveem K, Jansson JH, Jöckel KH, Kessler T, Kriebel J, Laugwitz KL, Marouli E, Martinelli N, McCarthy MI, Van Zuydam NR, Meisinger C, Esko T, Mihailov E, Escher SA, Alver M, Moebus S, Morris AD, Müller-Nurasyid M, Nikpay M, Olivieri O, Lemieux Perreault LP, AlQarawi A, Robertson NR, Akinsanya KO, Reilly DF, Vogt TF, Yin W, Asselbergs FW, Kooperberg C, Jackson RD, Stahl E, Strauch K, Varga TV, Waldenberger M, Zeng L, Kraja AT, Liu C, Ehret GB, Newton-Cheh C, Chasman DI, Chowdhury R, Ferrario M, Ford I, Jukema JW, Kee F, Kuulasmaa K, Nordestgaard BG, Perola M, Saleheen D, Sattar N, Surendran P, Tregouet D, Young R, Howson JM, Butterworth AS, Danesh J, Ardissino D, Bottinger EP, Erbel R, Franks PW, Girelli D, Hall AS, Hovingh GK, Kastrati A, Lieb W, Meitinger T, Kraus WE, Shah SH, McPherson R, Orho-Melander M, Melander O, Metspalu A, Palmer CN, Peters A, Rader D, Reilly MP, Loos RJ, Reiner AP, Roden DM, Tardif JC, Thompson JR, Wareham NJ, Watkins H, Willer CJ, Kathiresan S, Deloukas P, Samani NJ, Schunkert H
  (2016) N Engl J Med 374: 1134-44
• Premature coronary-artery atherosclerosis in systemic lupus erythematosus.
  Asanuma Y, Oeser A, Shintani AK, Turner E, Olsen N, Fazio S, Linton MF, Raggi P, Stein CM
  (2003) N Engl J Med 349: 2407-15
• APOL1 risk variants, race, and progression of chronic kidney disease.
  Parsa A, Kao WH, Xie D, Astor BC, Li M, Hsu CY, Feldman HI, Parekh RS, Kusek JW, Greene TH, Fink JC, Anderson AH, Choi MJ, Wright JT, Lash JP, Freedman BI, Ojo A, Winkler CA, Raj DS, Kopp JB, He J, Jensvold NG, Tao K, Lipkowitz MS, Appel LJ, AASK Study Investigators, CRIC Study Investigators
  (2013) N Engl J Med 369: 2183-96
• A unified framework for joint-tissue transcriptome-wide association and Mendelian randomization analysis.
  Zhou D, Jiang Y, Zhong X, Cox NJ, Liu C, Gamazon ER
  (2020) Nat Genet 52: 1239-1246
• Prevention of atherosclerosis in apolipoprotein E-deficient mice by bone marrow transplantation.
  Linton MF, Atkinson JB, Fazio S
  (1995) Science 267: 1034-7
• Genetic variants and associations of 25-hydroxyvitamin D concentrations with major clinical outcomes.
  Levin GP, Robinson-Cohen C, de Boer IH, Houston DK, Lohman K, Liu Y, Kritchevsky SB, Cauley JA, Tanaka T, Ferrucci L, Bandinelli S, Patel KV, Hagström E, Michaëlsson K, Melhus H, Wang T, Wolf M, Psaty BM, Siscovick D, Kestenbaum B
  (2012) JAMA 308: 1898-905
• Noninvasive multiphoton fluorescence microscopy resolves retinol and retinal condensation products in mouse eyes.
  Palczewska G, Maeda T, Imanishi Y, Sun W, Chen Y, Williams DR, Piston DW, Maeda A, Palczewski K
  (2010) Nat Med 16: 1444-9
• Decrease in antibiotic use, an added benefit of PCVs.
  Grijalva CG
  (2014) Lancet Infect Dis 14: 175-7
• Antipsychotic-like Effects of M4 Positive Allosteric Modulators Are Mediated by CB2 Receptor-Dependent Inhibition of Dopamine Release.
  Foster DJ, Wilson JM, Remke DH, Mahmood MS, Uddin MJ, Wess J, Patel S, Marnett LJ, Niswender CM, Jones CK, Xiang Z, Lindsley CW, Rook JM, Conn PJ
  (2016) Neuron 91: 1244-1252
• CaMKII regulates diacylglycerol lipase-α and striatal endocannabinoid signaling.
  Shonesy BC, Wang X, Rose KL, Ramikie TS, Cavener VS, Rentz T, Baucum AJ, Jalan-Sakrikar N, Mackie K, Winder DG, Patel S, Colbran RJ
  (2013) Nat Neurosci 16: 456-63
• Response by Mueller et al to Letter Regarding Article, "Deletion of Macrophage Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Accelerates Atherosclerosis Regression and Increases C-C Chemokine Receptor Type 7 (CCR7) Expression in Plaque Macrophages".
  Mueller PA, Zhu L, Tavori H, Huynh KT, Giunzioni I, Stafford JM, Linton MF, Fazio S
  (2019) Circulation 139: 1983-1984
• Interplay between apolipoprotein E and scavenger receptor class B type I controls coronary atherosclerosis and lifespan in the mouse.
  Fazio S, Linton MF
  (2005) Circulation 111: 3349-51
• Macrophage expression of peroxisome proliferator-activated receptor-alpha reduces atherosclerosis in low-density lipoprotein receptor-deficient mice.
  Babaev VR, Ishiguro H, Ding L, Yancey PG, Dove DE, Kovacs WJ, Semenkovich CF, Fazio S, Linton MF
  (2007) Circulation 116: 1404-12
• Low-density lipoprotein receptor-related protein 1 prevents early atherosclerosis by limiting lesional apoptosis and inflammatory Ly-6Chigh monocytosis: evidence that the effects are not apolipoprotein E dependent.
  Yancey PG, Ding Y, Fan D, Blakemore JL, Zhang Y, Ding L, Zhang J, Linton MF, Fazio S
  (2011) Circulation 124: 454-64
• Inactivation of macrophage scavenger receptor class B type I promotes atherosclerotic lesion development in apolipoprotein E-deficient mice.
  Zhang W, Yancey PG, Su YR, Babaev VR, Zhang Y, Fazio S, Linton MF
  (2003) Circulation 108: 2258-63
• LPA Variants Are Associated With Residual Cardiovascular Risk in Patients Receiving Statins.
  Wei WQ, Li X, Feng Q, Kubo M, Kullo IJ, Peissig PL, Karlson EW, Jarvik GP, Lee MTM, Shang N, Larson EA, Edwards T, Shaffer CM, Mosley JD, Maeda S, Horikoshi M, Ritchie M, Williams MS, Larson EB, Crosslin DR, Bland ST, Pacheco JA, Rasmussen-Torvik LJ, Cronkite D, Hripcsak G, Cox NJ, Wilke RA, Stein CM, Rotter JI, Momozawa Y, Roden DM, Krauss RM, Denny JC
  (2018) Circulation 138: 1839-1849
• Established and emerging plasma biomarkers in the prediction of first atherothrombotic events.
  Ridker PM, Brown NJ, Vaughan DE, Harrison DG, Mehta JL
  (2004) Circulation 109: IV6-19
• Deletion of Macrophage Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Accelerates Atherosclerosis Regression and Increases C-C Chemokine Receptor Type 7 (CCR7) Expression in Plaque Macrophages.
  Mueller PA, Zhu L, Tavori H, Huynh K, Giunzioni I, Stafford JM, Linton MF, Fazio S
  (2018) Circulation 138: 1850-1863
• Dysfunctional high-density lipoprotein in patients on chronic hemodialysis.
  Yamamoto S, Yancey PG, Ikizler TA, Jerome WG, Kaseda R, Cox B, Bian A, Shintani A, Fogo AB, Linton MF, Fazio S, Kon V
  (2012) J Am Coll Cardiol 60: 2372-9
• Apolipoprotein L1 Variants and Blood Pressure Traits in African Americans.
  Nadkarni GN, Galarneau G, Ellis SB, Nadukuru R, Zhang J, Scott SA, Schurmann C, Li R, Rasmussen-Torvik LJ, Kho AN, Hayes MG, Pacheco JA, Manolio TA, Chisholm RL, Roden DM, Denny JC, Kenny EE, Bottinger EP
  (2017) J Am Coll Cardiol 69: 1564-1574
• Single-Cell Analyses Confirm the Critical Role of LRP6 for Wnt Signaling in APC-Deficient Cells.
  Cabel CR, Alizadeh E, Robbins DJ, Ahmed Y, Lee E, Thorne CA
  (2019) Dev Cell 49: 827-828
• Isolation and characterization of hepatic Golgi lipoproteins from hypercholesterolemic rats.
  Swift LL, Manowitz NR, Dunn GD, LeQuire VS
  (1980) J Clin Invest 66: 415-25
• Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice.
  Cyrus T, Witztum JL, Rader DJ, Tangirala R, Fazio S, Linton MF, Funk CD
  (1999) J Clin Invest 103: 1597-604
• Hepatic apo E expression is required for remnant lipoprotein clearance in the absence of the low density lipoprotein receptor.
  Linton MF, Hasty AH, Babaev VR, Fazio S
  (1998) J Clin Invest 101: 1726-36
• Elevated cholesterol and bile acid synthesis in an adult patient with homozygous familial hypercholesterolemia. Reduction by a high glucose diet.
  Stacpoole PW, Grundy SM, Swift LL, Greene HL, Slonim AE, Burr IM
  (1981) J Clin Invest 68: 1166-71
• Formation of non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in plasma and low density lipoprotein exposed to oxidative stress in vitro.
  Lynch SM, Morrow JD, Roberts LJ, Frei B
  (1994) J Clin Invest 93: 998-1004
• Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation.
  Linton MF, Gish R, Hubl ST, Bütler E, Esquivel C, Bry WI, Boyles JK, Wardell MR, Young SG
  (1991) J Clin Invest 88: 270-81
• Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and lipoprotein(a).
  Linton MF, Farese RV, Chiesa G, Grass DS, Chin P, Hammer RE, Hobbs HH, Young SG
  (1993) J Clin Invest 92: 3029-37
• Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo.
  Babaev VR, Fazio S, Gleaves LA, Carter KJ, Semenkovich CF, Linton MF
  (1999) J Clin Invest 103: 1697-705
• Control of very low-density lipoprotein secretion by N-ethylmaleimide-sensitive factor and miR-33.
  Allen RM, Marquart TJ, Jesse JJ, Baldán A
  (2014) Circ Res 115: 10-22