Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms. Chen L, Chetkovich DM, Petralia RS, Sweeney NT, Kawasaki Y, Wenthold RJ, Bredt DS, Nicoll RA (2000) Nature 408: 936-43 PSD-95 involvement in maturation of excitatory synapses. El-Husseini AE, Schnell E, Chetkovich DM, Nicoll RA, Bredt DS (2000) Science 290: 1364-8 Dual palmitoylation of PSD-95 mediates its vesiculotubular sorting, postsynaptic targeting, and ion channel clustering. El-Husseini AE, Craven SE, Chetkovich DM, Firestein BL, Schnell E, Aoki C, Bredt DS (2000) J Cell Biol 148: 159-72 Postsynaptic targeting of alternative postsynaptic density-95 isoforms by distinct mechanisms. Chetkovich DM, Bunn RC, Kuo SH, Kawasaki Y, Kohwi M, Bredt DS (2002) J Neurosci 22: 6415-25 AMPA receptor synaptic targeting regulated by stargazin interactions with the Golgi-resident PDZ protein nPIST. Cuadra AE, Kuo SH, Kawasaki Y, Bredt DS, Chetkovich DM (2004) J Neurosci 24: 7491-502 Impaired cognition, sensorimotor gating, and hippocampal long-term depression in mice lacking the prostaglandin E2 EP2 receptor. Savonenko A, Munoz P, Melnikova T, Wang Q, Liang X, Breyer RM, Montine TJ, Kirkwood A, Andreasson K (2009) Exp Neurol 217: 63-73 Regulation of stargazin synaptic trafficking by C-terminal PDZ ligand phosphorylation in bidirectional synaptic plasticity. Stein EL, Chetkovich DM (2010) J Neurochem 113: 42-53 Simultaneous prediction of binding free energy and specificity for PDZ domain-peptide interactions. Crivelli JJ, Lemmon G, Kaufmann KW, Meiler J (2013) J Comput Aided Mol Des 27: 1051-65
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