Knock, knock: who's there?: Nox1. Itani HA, Dikalov S, Harrison DG (2013) Circulation 127: 1850-2 Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice. Dikalova A, Clempus R, Lassègue B, Cheng G, McCoy J, Dikalov S, San Martin A, Lyle A, Weber DS, Weiss D, Taylor WR, Schmidt HH, Owens GK, Lambeth JD, Griendling KK (2005) Circulation 112: 2668-76 Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress induces monocyte adhesion by stimulating reactive oxygen species production from a nox1-based NADPH oxidase. Sorescu GP, Song H, Tressel SL, Hwang J, Dikalov S, Smith DA, Boyd NL, Platt MO, Lassègue B, Griendling KK, Jo H (2004) Circ Res 95: 773-9 Role of extracellular superoxide dismutase in hypertension. Gongora MC, Qin Z, Laude K, Kim HW, McCann L, Folz JR, Dikalov S, Fukai T, Harrison DG (2006) Hypertension 48: 473-81 A critical role for chloride channel-3 (CIC-3) in smooth muscle cell activation and neointima formation. Chu X, Filali M, Stanic B, Takapoo M, Sheehan A, Bhalla R, Lamb FS, Miller FJ (2011) Arterioscler Thromb Vasc Biol 31: 345-51 Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production. Dikalov SI, Dikalova AE, Bikineyeva AT, Schmidt HH, Harrison DG, Griendling KK (2008) Free Radic Biol Med 45: 1340-51 c-Jun N-terminal kinase attenuates TNFα signaling by reducing Nox1-dependent endosomal ROS production in vascular smooth muscle cells. Choi H, Dikalova A, Stark RJ, Lamb FS (2015) Free Radic Biol Med 86: 219-27 Functional association of nox1 with p22phox in vascular smooth muscle cells. Hanna IR, Hilenski LL, Dikalova A, Taniyama Y, Dikalov S, Lyle A, Quinn MT, Lassègue B, Griendling KK (2004) Free Radic Biol Med 37: 1542-9 LRRC8A channels support TNFα-induced superoxide production by Nox1 which is required for receptor endocytosis. Choi H, Ettinger N, Rohrbough J, Dikalova A, Nguyen HN, Lamb FS (2016) Free Radic Biol Med 101: 413-423 Apoptosis signal-regulating kinase 1 activation by Nox1-derived oxidants is required for TNFα receptor endocytosis. Choi H, Stark RJ, Raja BS, Dikalova A, Lamb FS (2019) Am J Physiol Heart Circ Physiol 316: H1528-H1537 Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncoupling. Dikalova AE, Góngora MC, Harrison DG, Lambeth JD, Dikalov S, Griendling KK (2010) Am J Physiol Heart Circ Physiol 299: H673-9 NADPH oxidases and reactive oxygen species at different stages of chronic hypoxia-induced pulmonary hypertension in newborn piglets. Dennis KE, Aschner JL, Milatovic D, Schmidt JW, Aschner M, Kaplowitz MR, Zhang Y, Fike CD (2009) Am J Physiol Lung Cell Mol Physiol 297: L596-607 Activation of NADPH oxidases leads to DNA damage in esophageal cells. Bhardwaj V, Gokulan RC, Horvat A, Yermalitskaya L, Korolkova O, Washington KM, El-Rifai W, Dikalov SI, Zaika AI (2017) Sci Rep 7: 9956
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.