P/CAF-mediated acetylation regulates the function of the basic helix-loop-helix transcription factor TAL1/SCL. Huang S, Qiu Y, Shi Y, Xu Z, Brandt SJ (2000) EMBO J 19: 6792-803 The SCL/TAL-1 gene is expressed in progenitors of both the hematopoietic and vascular systems during embryogenesis. Kallianpur AR, Jordan JE, Brandt SJ (1994) Blood 83: 1200-8 Expression of the TAL1/SCL transcription factor in physiological and pathological vascular processes. Tang T, Shi Y, Opalenik SR, Brantley-Sieders DM, Chen J, Davidson JM, Brandt SJ (2006) J Pathol 210: 121-9 p300 functions as a transcriptional coactivator for the TAL1/SCL oncoprotein. Huang S, Qiu Y, Stein RW, Brandt SJ (1999) Oncogene 18: 4958-67 The TAL1/SCL transcription factor regulates cell cycle progression and proliferation in differentiating murine bone marrow monocyte precursors. Dey S, Curtis DJ, Jane SM, Brandt SJ (2010) Mol Cell Biol 30: 2181-92 Transcriptional link between blood and bone: the stem cell leukemia gene and its +19 stem cell enhancer are active in bone cells. Pimanda JE, Silberstein L, Dominici M, Dekel B, Bowen M, Oldham S, Kallianpur A, Brandt SJ, Tannahill D, Göttgens B, Green AR (2006) Mol Cell Biol 26: 2615-25 Identification of a TAL1 target gene reveals a positive role for the LIM domain-binding protein Ldb1 in erythroid gene expression and differentiation. Xu Z, Huang S, Chang LS, Agulnick AD, Brandt SJ (2003) Mol Cell Biol 23: 7585-99 A mutant receptor tyrosine phosphatase, CD148, causes defects in vascular development. Takahashi T, Takahashi K, St John PL, Fleming PA, Tomemori T, Watanabe T, Abrahamson DR, Drake CJ, Shirasawa T, Daniel TO (2003) Mol Cell Biol 23: 1817-31 mSin3A regulates murine erythroleukemia cell differentiation through association with the TAL1 (or SCL) transcription factor. Huang S, Brandt SJ (2000) Mol Cell Biol 20: 2248-59 Mitogen-activated protein kinase mediates erythropoietin-induced phosphorylation of the TAL1/SCL transcription factor in murine proerythroblasts. Tang T, Prasad KS, Koury MJ, Brandt SJ (1999) Biochem J 343 Pt 3: 615-20 Tal1/SCL binding to pericentromeric DNA represses transcription. Wen J, Huang S, Pack SD, Yu X, Brandt SJ, Noguchi CT (2005) J Biol Chem 280: 12956-66 Phosphorylation by mitogen-activated protein kinase mediates the hypoxia-induced turnover of the TAL1/SCL transcription factor in endothelial cells. Tang T, Arbiser JL, Brandt SJ (2002) J Biol Chem 277: 18365-72 Erythropoietin stimulates transcription of the TAL1/SCL gene and phosphorylation of its protein products. Prasad KS, Jordan JE, Koury MJ, Bondurant MC, Brandt SJ (1995) J Biol Chem 270: 11603-11 Target-dependent effect of phosphorylation on the DNA binding activity of the TAL1/SCL oncoprotein. Prasad KS, Brandt SJ (1997) J Biol Chem 272: 11457-62 TAL1/SCL is expressed in endothelial progenitor cells/angioblasts and defines a dorsal-to-ventral gradient of vasculogenesis. Drake CJ, Brandt SJ, Trusk TC, Little CD (1997) Dev Biol 192: 17-30 Eto2/MTG16 and MTGR1 are heteromeric corepressors of the TAL1/SCL transcription factor in murine erythroid progenitors. Cai Y, Xu Z, Xie J, Ham AJ, Koury MJ, Hiebert SW, Brandt SJ (2009) Biochem Biophys Res Commun 390: 295-301
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