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Creative Data Solutions (CDS) is a Vanderbilt Shared Resource and has extensive experience in providing effective and robust solutions to challenges pertaining to research data using modern informatics and bioinformatics approaches.
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Connections to Rapamycin-Insensitive Companion of mTOR Protein are shown below. Double-click or tap a node for more information.
Please note that publication matches are limited to 40 in this view. If you expected more, please view all publication matches for Rapamycin-Insensitive Companion of mTOR Protein.
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- mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice.
Guertin DA, Stevens DM, Saitoh M, Kinkel S, Crosby K, Sheen JH, Mullholland DJ, Magnuson MA, Wu H, Sabatini DM
(2009) Cancer Cell 15: 148-59 - Vital roles of mTOR complex 2 in Notch-driven thymocyte differentiation and leukemia.
Lee K, Nam KT, Cho SH, Gudapati P, Hwang Y, Park DS, Potter R, Chen J, Volanakis E, Boothby M
(2012) J Exp Med 209: 713-28 - Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability.
Shiota C, Woo JT, Lindner J, Shelton KD, Magnuson MA
(2006) Dev Cell 11: 583-9 - The targeted podocyte.
Fogo AB
(2011) J Clin Invest 121: 2142-5 - Requirement for Rictor in homeostasis and function of mature B lymphoid cells.
Lee K, Heffington L, Jellusova J, Nam KT, Raybuck A, Cho SH, Thomas JW, Rickert RC, Boothby M
(2013) Blood 122: 2369-79 - Selective mTORC2 Inhibitor Therapeutically Blocks Breast Cancer Cell Growth and Survival.
Werfel TA, Wang S, Jackson MA, Kavanaugh TE, Joly MM, Lee LH, Hicks DJ, Sanchez V, Ericsson PG, Kilchrist KV, Dimobi SC, Sarett SM, Brantley-Sieders DM, Cook RS, Duvall CL
(2018) Cancer Res 78: 1845-1858 - Rictor/mTORC2 Drives Progression and Therapeutic Resistance of HER2-Amplified Breast Cancers.
Morrison Joly M, Hicks DJ, Jones B, Sanchez V, Estrada MV, Young C, Williams M, Rexer BN, Sarbassov dos D, Muller WJ, Brantley-Sieders D, Cook RS
(2016) Cancer Res 76: 4752-64 - Rictor/mTORC2 deficiency enhances keratinocyte stress tolerance via mitohormesis.
Tassone B, Saoncella S, Neri F, Ala U, Brusa D, Magnuson MA, Provero P, Oliviero S, Riganti C, Calautti E
(2017) Cell Death Differ 24: 731-746 - Fat cell-specific ablation of rictor in mice impairs insulin-regulated fat cell and whole-body glucose and lipid metabolism.
Kumar A, Lawrence JC, Jung DY, Ko HJ, Keller SR, Kim JK, Magnuson MA, Harris TE
(2010) Diabetes 59: 1397-406 - Rictor/mTORC2 is essential for maintaining a balance between beta-cell proliferation and cell size.
Gu Y, Lindner J, Kumar A, Yuan W, Magnuson MA
(2011) Diabetes 60: 827-37 - Deletion of Rictor in neural progenitor cells reveals contributions of mTORC2 signaling to tuberous sclerosis complex.
Carson RP, Fu C, Winzenburger P, Ess KC
(2013) Hum Mol Genet 22: 140-52 - Rictor is a novel target of p70 S6 kinase-1.
Treins C, Warne PH, Magnuson MA, Pende M, Downward J
(2010) Oncogene 29: 1003-16 - mTORC2/rictor signaling disrupts dopamine-dependent behaviors via defects in striatal dopamine neurotransmission.
Dadalko OI, Siuta M, Poe A, Erreger K, Matthies HJ, Niswender K, Galli A
(2015) J Neurosci 35: 8843-54 - Evaluation of diffusion kurtosis imaging in ex vivo hypomyelinated mouse brains.
Kelm ND, West KL, Carson RP, Gochberg DF, Ess KC, Does MD
(2016) Neuroimage 124: 612-626 - Regulation of endothelial cell proliferation and vascular assembly through distinct mTORC2 signaling pathways.
Wang S, Amato KR, Song W, Youngblood V, Lee K, Boothby M, Brantley-Sieders DM, Chen J
(2015) Mol Cell Biol 35: 1299-313 - Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances Basal glycogen synthase activity.
Kumar A, Harris TE, Keller SR, Choi KM, Magnuson MA, Lawrence JC
(2008) Mol Cell Biol 28: 61-70 - A Rictor-Myo1c complex participates in dynamic cortical actin events in 3T3-L1 adipocytes.
Hagan GN, Lin Y, Magnuson MA, Avruch J, Czech MP
(2008) Mol Cell Biol 28: 4215-26 - Cooperative signaling between Slit2 and Ephrin-A1 regulates a balance between angiogenesis and angiostasis.
Dunaway CM, Hwang Y, Lindsley CW, Cook RS, Wu JY, Boothby M, Chen J, Brantley-Sieders DM
(2011) Mol Cell Biol 31: 404-16 - Identification of Protor as a novel Rictor-binding component of mTOR complex-2.
Pearce LR, Huang X, Boudeau J, Pawłowski R, Wullschleger S, Deak M, Ibrahim AF, Gourlay R, Magnuson MA, Alessi DR
(2007) Biochem J 405: 513-22 - Rictor phosphorylation on the Thr-1135 site does not require mammalian target of rapamycin complex 2.
Boulbes D, Chen CH, Shaikenov T, Agarwal NK, Peterson TR, Addona TA, Keshishian H, Carr SA, Magnuson MA, Sabatini DM, Sarbassov dos D
(2010) Mol Cancer Res 8: 896-906 - Loss of mTORC2 signaling in oligodendrocyte precursor cells delays myelination.
Grier MD, West KL, Kelm ND, Fu C, Does MD, Parker B, McBrier E, Lagrange AH, Ess KC, Carson RP
(2017) PLoS One 12: e0188417 - mTORC2 regulates cardiac response to stress by inhibiting MST1.
Sciarretta S, Zhai P, Maejima Y, Del Re DP, Nagarajan N, Yee D, Liu T, Magnuson MA, Volpe M, Frati G, Li H, Sadoshima J
(2015) Cell Rep 11: 125-36
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