Deterministic direct reprogramming of somatic cells to pluripotency. Rais Y, Zviran A, Geula S, Gafni O, Chomsky E, Viukov S, Mansour AA, Caspi I, Krupalnik V, Zerbib M, Maza I, Mor N, Baran D, Weinberger L, Jaitin DA, Lara-Astiaso D, Blecher-Gonen R, Shipony Z, Mukamel Z, Hagai T, Gilad S, Amann-Zalcenstein D, Tanay A, Amit I, Novershtern N, Hanna JH (2013) Nature 502: 65-70 Genetic engineering of human pluripotent cells using TALE nucleases. Hockemeyer D, Wang H, Kiani S, Lai CS, Gao Q, Cassady JP, Cost GJ, Zhang L, Santiago Y, Miller JC, Zeitler B, Cherone JM, Meng X, Hinkley SJ, Rebar EJ, Gregory PD, Urnov FD, Jaenisch R (2011) Nat Biotechnol 29: 731-4 The Promise of Cardiac Regeneration by In Situ Lineage Conversion. Nam YJ, Munshi NV (2017) Circulation 135: 914-916 Stem cell-derived cardiomyocytes as a tool for studying proarrhythmia: a better canary in the coal mine? Roden DM, Hong CC (2013) Circulation 127: 1641-3 β-Aminoisobutyric acid induces browning of white fat and hepatic β-oxidation and is inversely correlated with cardiometabolic risk factors. Roberts LD, Boström P, O'Sullivan JF, Schinzel RT, Lewis GD, Dejam A, Lee YK, Palma MJ, Calhoun S, Georgiadi A, Chen MH, Ramachandran VS, Larson MG, Bouchard C, Rankinen T, Souza AL, Clish CB, Wang TJ, Estall JL, Soukas AA, Cowan CA, Spiegelman BM, Gerszten RE (2014) Cell Metab 19: 96-108 Matrigel Mattress: A Method for the Generation of Single Contracting Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Feaster TK, Cadar AG, Wang L, Williams CH, Chun YW, Hempel JE, Bloodworth N, Merryman WD, Lim CC, Wu JC, Knollmann BC, Hong CC (2015) Circ Res 117: 995-1000 Induced pluripotent stem cell-derived cardiomyocytes: boutique science or valuable arrhythmia model? Knollmann BC (2013) Circ Res 112: 969-76; discussion 976 Precision Modeling of Pulmonary Hypertension Pathology with Induced Pluripotent Stem Cell-derived Cells. West JD, Carrier EJ (2018) Am J Respir Crit Care Med 198: 154-155 High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells. Sharma A, Burridge PW, McKeithan WL, Serrano R, Shukla P, Sayed N, Churko JM, Kitani T, Wu H, Holmström A, Matsa E, Zhang Y, Kumar A, Fan AC, Del Álamo JC, Wu SM, Moslehi JJ, Mercola M, Wu JC (2017) Sci Transl Med 9: A novel model of urinary tract differentiation, tissue regeneration, and disease: reprogramming human prostate and bladder cells into induced pluripotent stem cells. Moad M, Pal D, Hepburn AC, Williamson SC, Wilson L, Lako M, Armstrong L, Hayward SW, Franco OE, Cates JM, Fordham SE, Przyborski S, Carr-Wilkinson J, Robson CN, Heer R (2013) Eur Urol 64: 753-61 Genomic landscape of human allele-specific DNA methylation. Fang F, Hodges E, Molaro A, Dean M, Hannon GJ, Smith AD (2012) Proc Natl Acad Sci U S A 109: 7332-7 Osteoblasts derived from induced pluripotent stem cells form calcified structures in scaffolds both in vitro and in vivo. Bilousova G, Jun du H, King KB, De Langhe S, Chick WS, Torchia EC, Chow KS, Klemm DJ, Roop DR, Majka SM (2011) Stem Cells 29: 206-16 Heterozygous loss of TSC2 alters p53 signaling and human stem cell reprogramming. Armstrong LC, Westlake G, Snow JP, Cawthon B, Armour E, Bowman AB, Ess KC (2017) Hum Mol Genet 26: 4629-4641 Combinatorial polymer matrices enhance in vitro maturation of human induced pluripotent stem cell-derived cardiomyocytes. Chun YW, Balikov DA, Feaster TK, Williams CH, Sheng CC, Lee JB, Boire TC, Neely MD, Bellan LM, Ess KC, Bowman AB, Sung HJ, Hong CC (2015) Biomaterials 67: 52-64 Modelling sarcomeric cardiomyopathies in the dish: from human heart samples to iPSC cardiomyocytes. Eschenhagen T, Mummery C, Knollmann BC (2015) Cardiovasc Res 105: 424-38 PARK2 patient neuroprogenitors show increased mitochondrial sensitivity to copper. Aboud AA, Tidball AM, Kumar KK, Neely MD, Han B, Ess KC, Hong CC, Erikson KM, Hedera P, Bowman AB (2015) Neurobiol Dis 73: 204-12 A temperature-sensitive, self-adhesive hydrogel to deliver iPSC-derived cardiomyocytes for heart repair. Wang X, Chun YW, Zhong L, Chiusa M, Balikov DA, Frist AY, Lim CC, Maltais S, Bellan L, Hong CC, Sung HJ (2015) Int J Cardiol 190: 177-80 Human induced pluripotent stem cell (hiPSC) derived cardiomyocytes to understand and test cardiac calcium handling: A glass half full. Hwang HS, Kryshtal DO, Feaster TK, Sánchez-Freire V, Zhang J, Kamp TJ, Hong CC, Wu JC, Knollmann BC (2015) J Mol Cell Cardiol 89: 379-80 Comparable calcium handling of human iPSC-derived cardiomyocytes generated by multiple laboratories. Hwang HS, Kryshtal DO, Feaster TK, Sánchez-Freire V, Zhang J, Kamp TJ, Hong CC, Wu JC, Knollmann BC (2015) J Mol Cell Cardiol 85: 79-88 Coordinated Proliferation and Differentiation of Human-Induced Pluripotent Stem Cell-Derived Cardiac Progenitor Cells Depend on Bone Morphogenetic Protein Signaling Regulation by GREMLIN 2. Bylund JB, Trinh LT, Awgulewitsch CP, Paik DT, Jetter C, Jha R, Zhang J, Nolan K, Xu C, Thompson TB, Kamp TJ, Hatzopoulos AK (2017) Stem Cells Dev 26: 678-693 Generation of familial amyloidotic polyneuropathy-specific induced pluripotent stem cells. Isono K, Jono H, Ohya Y, Shiraki N, Yamazoe T, Sugasaki A, Era T, Fusaki N, Tasaki M, Ueda M, Shinriki S, Inomata Y, Kume S, Ando Y (2014) Stem Cell Res 12: 574-83 DMH1, a highly selective small molecule BMP inhibitor promotes neurogenesis of hiPSCs: comparison of PAX6 and SOX1 expression during neural induction. Neely MD, Litt MJ, Tidball AM, Li GG, Aboud AA, Hopkins CR, Chamberlin R, Hong CC, Ess KC, Bowman AB (2012) ACS Chem Neurosci 3: 482-91 Genomic Instability Associated with p53 Knockdown in the Generation of Huntington's Disease Human Induced Pluripotent Stem Cells. Tidball AM, Neely MD, Chamberlin R, Aboud AA, Kumar KK, Han B, Bryan MR, Aschner M, Ess KC, Bowman AB (2016) PLoS One 11: e0150372 Programmatic change: lung disease research in the era of induced pluripotency. Ikonomou L, Hemnes AR, Bilousova G, Hamid R, Loyd JE, Hatzopoulos AK, Kotton DN, Majka SM, Austin ED (2011) Am J Physiol Lung Cell Mol Physiol 301: L830-5 Differential responses of induced pluripotent stem cell-derived cardiomyocytes to anisotropic strain depends on disease status. Chun YW, Voyles DE, Rath R, Hofmeister LH, Boire TC, Wilcox H, Lee JH, Bellan LM, Hong CC, Sung HJ (2015) J Biomech 48: 3890-6 The potential of induced pluripotent stem cells as a translational model for neurotoxicological risk. Kumar KK, Aboud AA, Bowman AB (2012) Neurotoxicology 33: 518-29 Phosphatidylinositol 3 kinase (PI3K) modulates manganese homeostasis and manganese-induced cell signaling in a murine striatal cell line. Bryan MR, Uhouse MA, Nordham KD, Joshi P, Rose DIR, O'Brien MT, Aschner M, Bowman AB (2018) Neurotoxicology 64: 185-194 Genetic risk for Parkinson's disease correlates with alterations in neuronal manganese sensitivity between two human subjects. Aboud AA, Tidball AM, Kumar KK, Neely MD, Ess KC, Erikson KM, Bowman AB (2012) Neurotoxicology 33: 1443-1449
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.