A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease. Graham RL, Becker MM, Eckerle LD, Bolles M, Denison MR, Baric RS (2012) Nat Med 18: 1820-6 Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice. Becker MM, Graham RL, Donaldson EF, Rockx B, Sims AC, Sheahan T, Pickles RJ, Corti D, Johnston RE, Baric RS, Denison MR (2008) Proc Natl Acad Sci U S A 105: 19944-9 Reverse genetics with a full-length infectious cDNA of severe acute respiratory syndrome coronavirus. Yount B, Curtis KM, Fritz EA, Hensley LE, Jahrling PB, Prentice E, Denison MR, Geisbert TW, Baric RS (2003) Proc Natl Acad Sci U S A 100: 12995-3000 Discovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus (SARS-CoV) 3CL protease. Jacobs J, Grum-Tokars V, Zhou Y, Turlington M, Saldanha SA, Chase P, Eggler A, Dawson ES, Baez-Santos YM, Tomar S, Mielech AM, Baker SC, Lindsley CW, Hodder P, Mesecar A, Stauffer SR (2013) J Med Chem 56: 534-46 Severe acute respiratory syndrome coronavirus pathogenesis, disease and vaccines: an update. Denison MR (2004) Pediatr Infect Dis J 23: S207-14 SARS coronavirus replicase proteins in pathogenesis. Graham RL, Sparks JS, Eckerle LD, Sims AC, Denison MR (2008) Virus Res 133: 88-100
Hints: (1) double-click or double-tap to navigate to a node. (2) Grab a node and move it to arrange the graph.